Karimkhani C , Green AC , Nijsten T , Weinstock MA , Dellavalle RP , Naghavi M , Fitzmaurice C , 2017. The global burden of melanoma: results from the Global Burden of Disease Study 2015. Br J Dermatol 177: 134–140.
Urban K , Mehrmal S , Uppal P , Giesey RL , Delost GR , 2021. The global burden of skin cancer: a longitudinal analysis from the Global Burden of Disease Study, 1990–2017. JAAD Int 2: 98–108.
Basurto-Lozada P et al.2021. 2020. Acral lentiginous melanoma: basic facts, biological characteristics and research perspectives of an understudied disease. Pigment Cell Melanoma Res 34: 59–71.
Jenkins RW , Fisher DE , 2021. Treatment of advanced melanoma in 2020 and beyond. J Invest Dermatol 141: 23–31.
Honeyman CS , Wilson P , 2016. Patient with giant upper limb melanoma presenting to a UK plastic surgery unit: differentials and experience of management. BMJ Case Rep 2016: bcr-2015-212253.
Ching J , Gould L , 2012. Giant scalp melanoma: a case report and review of the literature. Eplasty 12: e51.
di Meo N , Stinco G , Gatti A , Errichetti E , Bonin S , Albano A , 2014. Giant melanoma of the abdomen: case report and revision of the published cases. Dermatol Online 20: 13030/qt4pp2825w.
Tseng WW , Doyle JA , Maguiness S , Horvai AE , Kashani-Sabet M , Leong SPL , 2009. Giant cutaneous melanomas: evidence for primary tumour induced dormancy in metastatic sites? Case Reports 2009: bcr0720092073.
Pai R , Kini H , Kamath SG , Kumar S , 2008. Giant hanging melanoma of the eyelid skin. Indian J Opthalmology 56: 239–240.
Kruijff S , Vink R , Klaase J , 2011. Salvage surgery for a giant melanoma on the back. Rare Tumors 3: 90–91.
Sung H , Ferlay J , Siegel RL , Laversanne M , Soerjomataram I , Jemal A , Bray F , 2021. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71: 209–249.
Asuquo M , Ebughe G , 2009. Cutaneous cancers in Calabar, southern Nigeria. Dermatol Online J 15: 11.
Mulenga M , Montgomery ND , Chagomerana M , Mzumala T , Tomoka T , Kampani C , Fedoriw Y , Gopal S , Sviland L , 2019. Epidemiological and histopathological profile of malignant melanoma in Malawi. BMC Clin Pathol 19: 1–6.
Meara JG et al.2015. Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development. Lancet 386: 569–624.
World Health Organization , 2021. A Strategic Framework for Integrated Control of Skin-Neglected Tropical Disease. Geneva, Switzerland: WHO.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 10011 | 10011 | 67 |
Full Text Views | 33 | 33 | 0 |
PDF Downloads | 35 | 35 | 0 |
Malignant melanoma is rare in West Africa. Few cases of giant melanoma have been reported globally. We present a case of acral melanoma with giant local recurrence on the foot of a black-skinned woman from rural Sierra Leone, managed with below-knee amputation. Atypical, late presentation, poor access to diagnostics, and underreporting may contribute to underappreciation of melanoma as a healthcare problem in West Africa. This case highlights the need for improved cancer and skin health surveillance structures in West Africa—most importantly, increasing access to histopathology.
Authors’ addresses: Harry Putnam, Alexandra Turnbull, James Bangura, and Jan Henk Dubbink, Masanga Medical Research Unit, Masanga Hospital, Tonkolili District, Sierra Leone, E-mails: putnamhwi@gmail.com, alexandraturnbull2@gmail.com, jashebangs@gmail.com, and janhenkdubbink@gmail.com. Panagiota Kitsanta, Histopathology Department, Royal Hallamshire Hospital, Sheffield, United Kingdom, E-mail: panagiota.kitsanta@nhs.net. Martin P. Grobusch, Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam University Medical Centers, Amsterdam, The Netherlands, E-mail: m.p.grobusch@amsterdamumc.nl.