ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
  McCarthy J , Moore TA , 2000. Emerging helminth zoonoses. Int J Parasitol 30: 1351–1360.
-
2.
  Cross JH , 1992. Intestinal capillariasis. Clin Microbiol Rev 5: 120–129.
-
3.
  Dronda F , Chaves F , Sanz A , Lopez-Velez R , 1993. Human intestinal capillariasis in an area of nonendemicity: case report and review. Clin Infect Dis 17: 909–912.
-
4.
  Saichua P , Nithikathkul C , Kaewpitoon N , 2008. Human intestinal capillariasis in Thailand. World J Gastroenterol 14: 506–510.
-
5.
  Sadaow L , Sanpool O , Intapan PM , Sukeepaisarnjaroen W , Prasongdee TK , Maleewong W , 2018. A hospital-based study of intestinal capillariasis in Thailand: clinical features, potential clues for diagnosis, and epidemiological characteristics of 85 patients. Am J Trop Med Hyg 98: 27–31.
-
6.
  Limsrivilai J , Pongprasobchai S , Apisarnthanarak P , Manatsathit S , 2014. Intestinal capillariasis in the 21st century: clinical presentations and role of endoscopy and imaging. BMC Gastroenterol 14: 207.
-
7.
  Rana SS , Bhasin DK , Bhatti HS , Gupta K , Gupta R , Nada R , Nagi B , Sinha SK , Singh K , 2009. Human intestinal capillariasis: diagnosis by jejunal fluid analysis obtained at enteroscopy and reversal of subtotal villous atrophy after treatment. Endoscopy 41: 102–103.
-
8.
  Khalifa MM , Abdel-Rahman SM , Bakir HY , Othman RA , El-Mokhtar MA , 2020. Comparison of the diagnostic performance of microscopic examination, Copro-ELISA, and Copro-PCR in the diagnosis of Capillaria philippinensis infections. PLOS ONE 15: e0234746.
-
9.
  El Dib NA , Sabry MA , Ahmed JA , El-Basiouni SO , El-Badry AA , 2004. Evaluation of Capillaria philippinensis coproantigen in the diagnosis of infection. J Egypt Soc Parasitol 34: 97–106.
-
10.
  Intapan PM , Maleewong W , Sukeepaisarnjaroen W , Morakote N , 2006. Potential use of Trichinella spiralis antigen for serodiagnosis of human capillariasis philippinensis by immunoblot analysis. Parasitol Res 98: 227–231.
-
11.
  Hassan MA , Basyoni MMA , Amer MF , Al-Antably ASA , 2020. Antigen recognition patterns of intestinal capillariasis using immunoblot-based serodiagnosis. Acta Parasitol 65: 899–905.
-
12.
  Intapan PM , Maleewong W , Sukeepaisarnjaroen W , Morakote N , 2010. An enzyme-linked immunosorbent assay as screening tool for human intestinal capillariasis. Southeast Asian J Trop Med Public Health 41: 298–305.
-
13.
  Intapan PM , Rodpai R , Sanpool O , Thanchomnang T , Sadaow L , Phosuk I , Maleewong W , 2017. Development and evaluation of a rapid diagnostic immunochromatographic device to detect antibodies in sera from intestinal capillariasis cases. Parasitol Res 116: 2443–2447.
-
14.
  Lu LH , Lin MR , Choi WM , Hwang KP , Hsu YH , Bair MJ , Liu JD , Wang TE , Liu TP , Chung WC , 2006. Human intestinal capillariasis (Capillaria philippinensis) in Taiwan. Am J Trop Med Hyg 74: 810–813.
-
15.
  Elkins DB , Haswell-Elkins M , Anderson RM , 1986. The epidemiology and control of intestinal helminths in the Pulicat lake region of southern India. I. Study design and pre- and post-treatment observations on Ascaris lumbricoides infection. Trans R Soc Trop Med Hyg 80: 774–792.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 4926 | 2873 | 385 |
| Full Text Views | 243 | 22 | 0 |
| PDF Downloads | 159 | 31 | 0 |
High Prevalence of Intestinal Capillariasis in Chronic Diarrhea Patients in Thailand: Serological Screening Using a Rapid Lateral-Flow Immunochromatographic Assay
Thidarat K. Prasongdee
Thidarat K. Prasongdee
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Thidarat K. Prasongdee in
Current site
Google Scholar
PubMed
Search for other papers by Thidarat K. Prasongdee in
Current site
Google Scholar
PubMed
Krongkaew Seesui
Krongkaew Seesui
Namphong Hospital, Khon Kaen, Thailand;
Search for other papers by Krongkaew Seesui in
Current site
Google Scholar
PubMed
Search for other papers by Krongkaew Seesui in
Current site
Google Scholar
PubMed
Phuangphaka Sadee
Phuangphaka Sadee
Clinical Immunology Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Phuangphaka Sadee in
Current site
Google Scholar
PubMed
Search for other papers by Phuangphaka Sadee in
Current site
Google Scholar
PubMed
Lakkhana Sadaow
Lakkhana Sadaow
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Lakkhana Sadaow in
Current site
Google Scholar
PubMed
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Lakkhana Sadaow in
Current site
Google Scholar
PubMed
Wattana Sukeepaisarnjaroen
Wattana Sukeepaisarnjaroen
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Wattana Sukeepaisarnjaroen in
Current site
Google Scholar
PubMed
Search for other papers by Wattana Sukeepaisarnjaroen in
Current site
Google Scholar
PubMed
Ratthaphol Kraiklang
Ratthaphol Kraiklang
Department of Public Health Administration, Health Promotion, Nutrition, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
Search for other papers by Ratthaphol Kraiklang in
Current site
Google Scholar
PubMed
Search for other papers by Ratthaphol Kraiklang in
Current site
Google Scholar
PubMed
Oranuch Sanpool
Oranuch Sanpool
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Oranuch Sanpool in
Current site
Google Scholar
PubMed
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Oranuch Sanpool in
Current site
Google Scholar
PubMed
Wanchai Maleewong
Wanchai Maleewong
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Wanchai Maleewong in
Current site
Google Scholar
PubMed
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Wanchai Maleewong in
Current site
Google Scholar
PubMed
Pewpan M. Intapan
Pewpan M. Intapan
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Pewpan M. Intapan in
Current site
Google Scholar
PubMed
Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand;
Search for other papers by Pewpan M. Intapan in
Current site
Google Scholar
PubMed
ABSTRACT.
Intestinal capillariasis is an emerging fish-borne helminthic disease caused by the round worm Capillaria philippinensis. Chronic infection may lead to death if the disease is misdiagnosed and inappropriate treatment is given. We used a rapid lateral-flow immunochromatographic test for screening of intestinal capillariasis in patients with chronic diarrhea. We screened 292 chronic diarrhea patients who had visited hospitals in Thailand. Sixty-six (22.6%) cases were positive according to the kit. All positive patients received mebendazole at 200 mg twice per day for 30 consecutive days or albendazole at 200 mg twice per day for 10 consecutive days. Later, stool concentration techniques, used to examine stool samples from all serologically positive individuals on three consecutive days, revealed C. philippinensis eggs, larvae, and/or adults. The kit is useful for screening and rapid diagnosis of intestinal capillariasis in chronic diarrhea patients in an endemic area for prevention of serious disease and facilitates treatment.
Author Notes
Financial support: This study was supported by a Distinguished Research Professor Grant from the Thailand Research Fund (Grant no. DPG6280002) and grants from the Khon Kaen University: Research and Graduate studies (Research Program grant) and Faculty of Medicine (WM, PMI, and OS, Grant no. RG63301). The fund providers had no role in study design, data collection/interpretation, or the decision to submit the work for publication.
Authors’ addresses: Thidarat K. Prasongdee, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, E-mail: thidpr@kku.ac.th. Krongkaew Seesui, Namphong Hospital, Khon Kaen, Thailand, E-mail: jeem.mee66@gmail.com. Phuangphaka Sadee, Clinical Immunology Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, E-mail: sphuan@kku.ac.th. Lakkhana Sadaow, Oranuch Sanpool, Wanchai Maleewong, and Pewpan M. Intapan, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, and Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand, E-mails: sadaow1986@gmail.com, sanpoolor@yahoo.com, wanch_ma@kku.ac.th, and pewpan@kku.ac.th. Wattana Sukeepaisarnjaroen, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, E-mail: swatta@kku.ac.th. Ratthaphol Kraiklang, Department of Public Health Administration, Health Promotion, Nutrition, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand, E-mail: ratthaphol.bc@gmail.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
  McCarthy J , Moore TA , 2000. Emerging helminth zoonoses. Int J Parasitol 30: 1351–1360.
-
2.
  Cross JH , 1992. Intestinal capillariasis. Clin Microbiol Rev 5: 120–129.
-
3.
  Dronda F , Chaves F , Sanz A , Lopez-Velez R , 1993. Human intestinal capillariasis in an area of nonendemicity: case report and review. Clin Infect Dis 17: 909–912.
-
4.
  Saichua P , Nithikathkul C , Kaewpitoon N , 2008. Human intestinal capillariasis in Thailand. World J Gastroenterol 14: 506–510.
-
5.
  Sadaow L , Sanpool O , Intapan PM , Sukeepaisarnjaroen W , Prasongdee TK , Maleewong W , 2018. A hospital-based study of intestinal capillariasis in Thailand: clinical features, potential clues for diagnosis, and epidemiological characteristics of 85 patients. Am J Trop Med Hyg 98: 27–31.
-
6.
  Limsrivilai J , Pongprasobchai S , Apisarnthanarak P , Manatsathit S , 2014. Intestinal capillariasis in the 21st century: clinical presentations and role of endoscopy and imaging. BMC Gastroenterol 14: 207.
-
7.
  Rana SS , Bhasin DK , Bhatti HS , Gupta K , Gupta R , Nada R , Nagi B , Sinha SK , Singh K , 2009. Human intestinal capillariasis: diagnosis by jejunal fluid analysis obtained at enteroscopy and reversal of subtotal villous atrophy after treatment. Endoscopy 41: 102–103.
-
8.
  Khalifa MM , Abdel-Rahman SM , Bakir HY , Othman RA , El-Mokhtar MA , 2020. Comparison of the diagnostic performance of microscopic examination, Copro-ELISA, and Copro-PCR in the diagnosis of Capillaria philippinensis infections. PLOS ONE 15: e0234746.
-
9.
  El Dib NA , Sabry MA , Ahmed JA , El-Basiouni SO , El-Badry AA , 2004. Evaluation of Capillaria philippinensis coproantigen in the diagnosis of infection. J Egypt Soc Parasitol 34: 97–106.
-
10.
  Intapan PM , Maleewong W , Sukeepaisarnjaroen W , Morakote N , 2006. Potential use of Trichinella spiralis antigen for serodiagnosis of human capillariasis philippinensis by immunoblot analysis. Parasitol Res 98: 227–231.
-
11.
  Hassan MA , Basyoni MMA , Amer MF , Al-Antably ASA , 2020. Antigen recognition patterns of intestinal capillariasis using immunoblot-based serodiagnosis. Acta Parasitol 65: 899–905.
-
12.
  Intapan PM , Maleewong W , Sukeepaisarnjaroen W , Morakote N , 2010. An enzyme-linked immunosorbent assay as screening tool for human intestinal capillariasis. Southeast Asian J Trop Med Public Health 41: 298–305.
-
13.
  Intapan PM , Rodpai R , Sanpool O , Thanchomnang T , Sadaow L , Phosuk I , Maleewong W , 2017. Development and evaluation of a rapid diagnostic immunochromatographic device to detect antibodies in sera from intestinal capillariasis cases. Parasitol Res 116: 2443–2447.
-
14.
  Lu LH , Lin MR , Choi WM , Hwang KP , Hsu YH , Bair MJ , Liu JD , Wang TE , Liu TP , Chung WC , 2006. Human intestinal capillariasis (Capillaria philippinensis) in Taiwan. Am J Trop Med Hyg 74: 810–813.
-
15.
  Elkins DB , Haswell-Elkins M , Anderson RM , 1986. The epidemiology and control of intestinal helminths in the Pulicat lake region of southern India. I. Study design and pre- and post-treatment observations on Ascaris lumbricoides infection. Trans R Soc Trop Med Hyg 80: 774–792.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 4926 | 2873 | 385 |
| Full Text Views | 243 | 22 | 0 |
| PDF Downloads | 159 | 31 | 0 |