• 1.

    Puthiyakunnon S et al.2014. Strongyloidiasis—an insight into its global prevalence and management. PLoS Negl Trop Dis 8: e3018.

  • 2.

    Schär F et al.2013. Strongyloides stercoralis: global distribution and risk factors. PLoS Negl Trop Dis 7: e2288.

  • 3.

    Keiser PB, Nutman TB , 2004. Strongyloides stercoralis in the immunocompromised population. Clin Microbiol Rev 17: 208217.

  • 4.

    Ahmadpour E, Ghanizadegan MA, Razavi A, Kangari M, Seyfi R, Shahdust M , 2019. Strongyloides stercoralis infection in human immunodeficiency virus‐infected patients and related risk factors: a systematic review and meta‐analysis. Transbound Emerg Dis 66: 22332243.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5.

    Buonfrate D et al.2013. Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis 13: 78.

  • 6.

    Mukaigawara M, Narita M, Shiiki S, Takayama Y, Takakura S, Kishaba T , 2020. Clinical characteristics of disseminated strongyloidiasis, Japan, 1975–2017. Emerg Infect Dis 26: 401408.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Ersöz Ş, Turgutalp H, Akdoğan R, Çobanoğlu Ü, Saygın İ, Mungan S, Özgür O , 2010. Gastric strongyloidiasis in a diabetic patient. Turk J Pathol 26: 7173.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8.

    Lam CS, Tong MK, Chan KM, Siu YP, 2006. Disseminated strongyloidiasis: a retrospective study of clinical course and outcome. Eur J Clin Microbiol Infect Dis 25: 1418.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Aramendia AA et al.2020. Epidemiology of intestinal helminthiases in a rural community of Ethiopia: is it time to expand control programs to include Strongyloides stercoralis and the entire community? PLoS Negl Trop Dis 14: e0008315.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Lessnau KD, Can S, Talavera W , 1993. Disseminated Strongyloides stercoralis in human immunodefciency virus-infected patients. Treatment failure and a review of the literature. Chest 104: 119122.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 11.

    Jaka H et al.2013. Strongyloides stercoralis infection presenting as an unusual cause of massive upper gastrointestinal bleeding in an immunosuppressed patient: a case report. Trop Doct 43: 4648.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12.

    Romero-Cabello R, Villagroy Gómez J, Hernández González M, Romero Feregrino R , 2012. Hyperinfection with Strongyloides stercoralis. BMJ Case Rep 30: bcr2012006819.

    • Search Google Scholar
    • Export Citation
  • 13.

    Meine GC, Dietz J, Rocha M, Mattos T, de Souza AR, Conteletti FR , 2004. Atypical gastric presentation of strongyloidiasis in HIV-infected patient-case report. Dig Liver Dis 36: 760762.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14.

    Malnick S, Somin M, Beilinson N, Basevitch A, Bregman G, Zimhony O , 2009. Strongyloides hyperinfection in Ethiopian immigrants in Israel. Isr Med Assoc J 11: 660663.

    • Search Google Scholar
    • Export Citation
  • 15.

    Thompson BF, Fry LC, Wells CD , 2004. Spectrum of GI strongyloidiasis: an endoscopic-pathologic study. Gastrointest Endosc 59: 906911.

  • 16.

    Mohamed R, Hamodat MM, Al-Abbadi MA , 2017. Gastric strongyloidiasis: report of 2 cases and brief review of the literature. Lab Med 48: 9396.

  • 17.

    Sebastian A, Muttath R, Madhavan I, Thomas V , 2014. A case of Strongyloides hyperinfection syndrome. Trop J Med Res 17: 140142.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

 

 

 

Case Report: Disseminated Strongloides stercoralis Presenting as an Ulcerated Gastric Mass in an HIV-1-Infected Patient

View More View Less
  • 1 Amin General Hospital, Addis Ababa, Ethiopia;
  • | 2 Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia;
  • | 3 Bacterial, Fungal and Zoonotic Diseases Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia;
  • | 4 Mekelle University College of Health Sciences, Mekelle, Ethiopia
Restricted access

ABSTRACT.

Disseminated Strongloides stercoralis is a common phenomenon among patients with immunosuppression. In this report, we present a case of disseminated Strongloides stercoralis presenting as a gastric mass in a 42-year-old male patient with a known history of HIV-1 infection and type 2 diabetes mellitus (T2DM). The patient presented with symptoms and signs suggestive of acute on chronic erosive gastritis, which included persistent vomiting. Endoscopic examination revealed a gastric mass with no signs of malignancy or dysplasia. There was noted to be chronic inflammation along with morphologic features consistent with the larvae and eggs of Strongloides nematodes in a biopsied gastric mass tissue and duodenum. The disease subsequently resulted in death despite the administration of ivermectin.

Author Notes

Address correspondence to Dawit Wolday, Mekelle University College of Health Sciences, Mekelle, Ethiopia. E-mails: dawit.wolday@mu.edu.et or dawwol@gmail.com

Authors’ addresses: Kassa Tameru and Mohammed Shikur, Internal Medicine, Amin General Hospital, Addis Ababa, Ethiopia, E-mails: ktameru@yahoo.com and mosmigemusa@hotmail.com. Bekure Tsegaye and Wondwossen Ergete, Pathology, Amin General Hospital, Addis Ababa, Ethiopia, E-mails: bekure_tsegaye@yahoo.com and wondwossen_ergete@yahoo.com. Adugna Abera and Geremew Tasew, Bacterial, Fungal and Zoonotic Diseases Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia, E-mails: adugnabe@yahoo.com and getas73@yahoo.com. Dawit Wolday, Medicine, Mekelle University College of Health Sciences, Mekelle, Ethiopia, E-mail: dawwol@gmail.com.

Save