• 1.

    Peng C, Li YJ, Huang DS, Guan P, 2020. Spatial-temporal distribution of human brucellosis in mainland China from 2004 to 2017 and an analysis of social and environmental factors. Environ Health Prev Med 25: 1.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Guan P, Wu W, Huang D, 2018. Trends of reported human brucellosis cases in mainland China from 2007 to 2017: an exponential smoothing time series analysis. Environ Health Prev Med 23: 23.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Wang Y et al., 2013. Human brucellosis, a heterogeneously distributed, delayed, and misdiagnosed disease in china. Clin Infect Dis 56: 750751.

  • 4.

    Cao LT, Liu HH, Li J, Yin XD, Duan Y, Wang J, 2020. Relationship of meteorological factors and human brucellosis in Hebei province, China. Sci Total Environ 703: 135491.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5.

    Lai S et al., 2017. Changing epidemiology of human brucellosis, China, 1955–2014. Emerg Infect Dis 23: 184194.

  • 6.

    Shi Y et al., 2019. Correction: clinical features of 2041 human brucellosis cases in China. PLoS One 14: e0219110.

  • 7.

    Njeru J, Melzer F, Wareth G, El-Adawy H, Henning K, Pletz MW, Heller R, Kariuki S, Fèvre E, Neubauer H, 2016. Human brucellosis in febrile patients seeking treatment at remote hospitals, northeastern Kenya, 2014–2015. Emerg Infect Dis 22: 21602164.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8.

    World Health Organization , 2006. Brucellosis in Humans and Animals. Geneva, Switzerland: WHO. Available at: http://www.who.int/csr/resources/publications/Brucellosis.pdf. Accessed May 18, 2021.

  • 9.

    Logan LK, Jacobs NM, McAuley JB, Weinstein RA, Anderson EJ, 2011. A multicenter retrospective study of childhood brucellosis in Chicago, Illinois from 1986 to 2008. Int J Infect Dis 15: e812e817.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Tsolia M, Drakonaki S, Messaritaki A, Farmakakis T, Kostaki M, Tsapra H, Karpathios T, 2002. Clinical features, complications and treatment outcome of childhood brucellosis in central Greece. J Infect 44: 257262.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 11.

    Franco MP, Mulder M, Gilman RH, Smits HL, 2007. Human brucellosis. Lancet Infect Dis 7: 775786.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

 

 

 

Analysis of Brucellosis Cases Between 2010 and 2020 in Guangdong Province, China

View More View Less
  • 1 Division of Laboratory Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China
Restricted access

ABSTRACT.

Brucellosis is a zoonotic disease with more than half a million people diagnosed worldwide. In China, 99% of cases were historically reported in the northern part of the country, and few were diagnosed in Guangdong province. Recently, Guangzhou has become as an emerging focus for brucellosis, with personal awareness of brucellosis and inexperience of clinicians hindering timely clinical diagnosis. To improve clinical management of this disease, we retrospectively analyzed 60 brucellosis cases from 2010 to 2020 in Guangdong Provincial People’s Hospital. There were no manifestation differences between southern and northern patients. However, 68.3% of patients lacked awareness of risk factors for Brucella infection. Therefore, to prevent its spread and avoid delays in diagnosis, implemented infected-animal control programs and enhanced education on brucellosis are necessary.

Author Notes

Address correspondence to Bing Gu, Division of Laboratory Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, No. 106 Zhongshan Second Road, Guangzhou 510080, Guangdong, China. E-mail: gb20031129@163.com

These authors contributed equally to this work and share first authorship.

Authors’ addresses: Xiaoxiao Wang, Yunhu Zhao, and Suling Liu, Division of Laboratory Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China, E-mails: 916092097@qq.com, zhaoyunhu@gdph.org.cn, and liuliu-sky@126.com.

Save