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RefWorks
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Zotero
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-
1.
Vidal JE, 2019. HIV-related cerebral toxoplasmosis revisited: current concepts and controversies of an old disease. J Int Assoc Provid AIDS Care 18: 2325958219867315.
-
2.
Serpa JA , Moran A , Goodman JC , Giordano TP , White AC Jr , 2007. Neurocysticercosis in the HIV era: a case report and review of the literature. Am J Trop Med Hyg 77: 113–117.
-
3.
Nash TE , Bustos JA , Garcia HH ; Cysticercosis Working Group in Perú, 2017. Disease centered around calcified Taenia solium granuloma. Trends Parasitol 33: 65–73.
-
4.
Del Brutto OH , Nash TE , White AC , Jr, Rajshekhar V , Wilkins PP , Singh G , Vasquez CM , Salgado P , Gilman RH , Garcia HH , 2017. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci 372: 202–210.
-
5.
Thakur KT , Boubour A , Saylor D , Das M , Bearden DR , Birbeck GL , 2019. Global HIV neurology: a comprehensive review. AIDS 33: 163–184.
-
6.
Celzo FG , 2013. Brain stones revisited-between a rock and a hard place. Insights Imaging 4: 625–635.
-
7.
Nash TE , Ware JM , Mahanty S , 2017. Natural history of patients with perilesional edema around Taenia solium calcified granulomas. J Infect Dis 215: 1141–1147.
-
8.
Del Brutto OH , Santibañez R , Noboa CA , Aguirre R , Díaz E , Alarcón TA , 1992. Epilepsy due to neurocysticercosis: analysis of 203 patients. Neurology 42: 389–392.
-
9.
Telles JP et al.2021. Neurological manifestations in people living with HIV/AIDS in the late cART era: a prospective observational study at a tertiary healthcare center in São Paulo, Brazil. HIV Res Clin Pract 22: 87–95.
-
10.
Jewell PD et al.2021. Neurocysticercosis and HIV/AIDS co-infection: a scoping review. Trop Med Int Health 26: 1140–1152.
-
11.
Nash T , 2012. Edema surrounding calcified calcified intracranial cysticerci: clinical manifestations, natural history, and treatment. Pathog Glob Health 106: 275–279.
-
12.
Pradhan S , Kathuria MK , Gupta RK , 2000. Perilesional gliosis and seizure outcome: a study based on magnetization transfer magnetic resonance imaging in patients with neurocysticercosis. Ann Neurol 48: 181–187.
-
13.
de Souza A , Nalini A , Kovoor JM , Yeshraj G , Siddalingaiah HS , Thennarasu K , 2011. Perilesional gliosis around solitary cerebral parenchymal cysticerci and long-term seizure outcome: a prospective study using serial magnetization transfer imaging. Epilepsia 52: 1918–1927.
-
14.
Bustos JA , Coyle CM , 2020. Brain calcification because of neurocysticercosis: a vast field to be explored. Curr Opin Infect Dis 33: 334–338.
-
15.
Laissy JP et al.1994. Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence. AJNR Am J Neuroradiol 15: 1773–1778.
-
16.
Martin-Blondel G , Alvarez M , Delobel P , Uro-Coste E , Cuzin L , Cuvinciuc V , Fillaux J , Massip P , Marchou B , 2011. Toxoplasmic encephalitis IRIS in HIV-infected patients: a case series and review of the literature. J Neurol Neurosurg Psychiatry 82: 691–693.
-
17.
van Bilsen WPH , van den Berg CHSB , Rijnders BJA , Brinkman K , Mulder JW , Gelinck LBS , Hoepelman AIM , Wit FWNM , van de Beek D , Prins JM , 2017. Immune reconstitution inflammatory syndrome associated with toxoplasmic encephalitis in HIV-infected patients. AIDS 31: 1415–1424.
-
18.
Del Brutto OH , 2013. Neurocysticercosis: new thoughts on controversial issues. Curr Opin Neurol 26: 289–294.
-
19.
Nash T , Garcia HH , 2011. Diagnosis and treatment of neurocysticercosis. Nat Rev Neurol 7: 584–594.
-
20.
White AC , Jr, Coyle CM , Rajshekhar V , Singh G , Hauser WA , Mohanty A , Garcia HH , Nash TE , 2018. Diagnosis and treatment of neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis 66: e49–e75.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 8319 | 1290 | 49 |
| Full Text Views | 328 | 17 | 0 |
| PDF Downloads | 224 | 19 | 0 |
Case Report: Calcified Cerebral Toxoplasmosis Associated with Perilesional Edema in People Living with HIV/AIDS: Case Series of a Presentation Mimicking Neurocysticercosis
José E. Vidal
José E. Vidal
Departamento de Neurologia, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil;
Divisão de Moléstias Infecciosas, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
LIM 49, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
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Divisão de Moléstias Infecciosas, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
LIM 49, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
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René L. M. Rivero
René L. M. Rivero
Setor de Radiologia, Divisão de Apoio ao Diagnóstico e Terapêutica, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil;
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Sigrid de Sousa dos Santos
Sigrid de Sousa dos Santos
Departamento de Medicina, Universidade Federal de São Carlos, São Carlos, Brazil;
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Bruno F. Guedes
Bruno F. Guedes
Departmento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;
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Hélio R. Gomes
Hélio R. Gomes
Departmento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;
LIM 14, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
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LIM 14, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;
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Augusto C. Penalva de Oliveira
Augusto C. Penalva de Oliveira
Departamento de Neurologia, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil;
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Hector H. Garcia
Hector H. Garcia
Centro de Salud Global, Universidad Peruana Cayetano Herédia, Lima, Peru;
Unidad de Cisticercosis, Instituto de Ciencias Neurológicas, Lima, Peru
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Unidad de Cisticercosis, Instituto de Ciencias Neurológicas, Lima, Peru
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ABSTRACT.
Perilesional edema, associated or not with neurological manifestations, is a well-characterized finding in cases of calcified neurocysticercosis. There are no previous reports of HIV-related calcified toxoplasmosis that mimics this presentation of neurocysticercosis. We report on five patients, four of them with new-onset neurological manifestations, who showed brain calcifications associated with perilesional edema. All cases had a history of HIV-related toxoplasmosis and current virological and immunological control of HIV infection. Similar to neurocysticercosis, brain calcified toxoplasmosis may cause perilesional edema and symptoms in people living with HIV/AIDS.
Author Notes
Authors’ addresses: José E. Vidal, Departamento de Neurologia, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil, Divisão de Moléstias Infecciosas, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, and LIM 49, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, E-mail: josevibe@gmail.com. René L. M. Rivero, Setor de Radiologia, Divisão de Apoio ao Diagnóstico e Terapêutica, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil, E-mail: reneleandro3@hotmail.com. Sigrid de Sousa dos Santos, Departamento de Medicina, Universidade Federal de São Carlos, São Carlos, Brazil, E-mail: sigridsantos@gmail.com. Bruno F. Guedes, Departmento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, E-mail: bruno.guedes@hc.fm.usp.br. Hélio R. Gomes, Departmento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, and LIM 14, Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, E-mail: helio.gomes@hc.fm.usp.br. Augusto C. Penalva de Oliveira, Departamento de Neurologia, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil, E-mail: rdcassia@uol.com.br. Hector H. Garcia, Centro de Salud Global, Universidad Peruana Cayetano Herédia, Lima, Peru, and Unidad de Cisticercosis, Instituto de Ciencias Neurológicas, Lima, Peru, E-mail: hhgarcia1@jhu.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Vidal JE, 2019. HIV-related cerebral toxoplasmosis revisited: current concepts and controversies of an old disease. J Int Assoc Provid AIDS Care 18: 2325958219867315.
-
2.
Serpa JA , Moran A , Goodman JC , Giordano TP , White AC Jr , 2007. Neurocysticercosis in the HIV era: a case report and review of the literature. Am J Trop Med Hyg 77: 113–117.
-
3.
Nash TE , Bustos JA , Garcia HH ; Cysticercosis Working Group in Perú, 2017. Disease centered around calcified Taenia solium granuloma. Trends Parasitol 33: 65–73.
-
4.
Del Brutto OH , Nash TE , White AC , Jr, Rajshekhar V , Wilkins PP , Singh G , Vasquez CM , Salgado P , Gilman RH , Garcia HH , 2017. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci 372: 202–210.
-
5.
Thakur KT , Boubour A , Saylor D , Das M , Bearden DR , Birbeck GL , 2019. Global HIV neurology: a comprehensive review. AIDS 33: 163–184.
-
6.
Celzo FG , 2013. Brain stones revisited-between a rock and a hard place. Insights Imaging 4: 625–635.
-
7.
Nash TE , Ware JM , Mahanty S , 2017. Natural history of patients with perilesional edema around Taenia solium calcified granulomas. J Infect Dis 215: 1141–1147.
-
8.
Del Brutto OH , Santibañez R , Noboa CA , Aguirre R , Díaz E , Alarcón TA , 1992. Epilepsy due to neurocysticercosis: analysis of 203 patients. Neurology 42: 389–392.
-
9.
Telles JP et al.2021. Neurological manifestations in people living with HIV/AIDS in the late cART era: a prospective observational study at a tertiary healthcare center in São Paulo, Brazil. HIV Res Clin Pract 22: 87–95.
-
10.
Jewell PD et al.2021. Neurocysticercosis and HIV/AIDS co-infection: a scoping review. Trop Med Int Health 26: 1140–1152.
-
11.
Nash T , 2012. Edema surrounding calcified calcified intracranial cysticerci: clinical manifestations, natural history, and treatment. Pathog Glob Health 106: 275–279.
-
12.
Pradhan S , Kathuria MK , Gupta RK , 2000. Perilesional gliosis and seizure outcome: a study based on magnetization transfer magnetic resonance imaging in patients with neurocysticercosis. Ann Neurol 48: 181–187.
-
13.
de Souza A , Nalini A , Kovoor JM , Yeshraj G , Siddalingaiah HS , Thennarasu K , 2011. Perilesional gliosis around solitary cerebral parenchymal cysticerci and long-term seizure outcome: a prospective study using serial magnetization transfer imaging. Epilepsia 52: 1918–1927.
-
14.
Bustos JA , Coyle CM , 2020. Brain calcification because of neurocysticercosis: a vast field to be explored. Curr Opin Infect Dis 33: 334–338.
-
15.
Laissy JP et al.1994. Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence. AJNR Am J Neuroradiol 15: 1773–1778.
-
16.
Martin-Blondel G , Alvarez M , Delobel P , Uro-Coste E , Cuzin L , Cuvinciuc V , Fillaux J , Massip P , Marchou B , 2011. Toxoplasmic encephalitis IRIS in HIV-infected patients: a case series and review of the literature. J Neurol Neurosurg Psychiatry 82: 691–693.
-
17.
van Bilsen WPH , van den Berg CHSB , Rijnders BJA , Brinkman K , Mulder JW , Gelinck LBS , Hoepelman AIM , Wit FWNM , van de Beek D , Prins JM , 2017. Immune reconstitution inflammatory syndrome associated with toxoplasmic encephalitis in HIV-infected patients. AIDS 31: 1415–1424.
-
18.
Del Brutto OH , 2013. Neurocysticercosis: new thoughts on controversial issues. Curr Opin Neurol 26: 289–294.
-
19.
Nash T , Garcia HH , 2011. Diagnosis and treatment of neurocysticercosis. Nat Rev Neurol 7: 584–594.
-
20.
White AC , Jr, Coyle CM , Rajshekhar V , Singh G , Hauser WA , Mohanty A , Garcia HH , Nash TE , 2018. Diagnosis and treatment of neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis 66: e49–e75.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 8319 | 1290 | 49 |
| Full Text Views | 328 | 17 | 0 |
| PDF Downloads | 224 | 19 | 0 |