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KaurU, ChakrabartiSS, GambhirIS, 2016.
Isoniazid induced metabolic acidosis and renal dysfunction in an elderly patient with chronic renal disease. Curr Drug Saf11: 181–183.
Isoniazid induced metabolic acidosis and renal dysfunction in an elderly patient with chronic renal disease. Curr Drug Saf11: 181–183.)| false
Isoniazid is an important component of first-line antitubercular therapy. The drug at its therapeutic dose is known to cause hepatitis and peripheral neuropathy. The association of isoniazid with pure delirium is rare. Here, we present an interesting case of new-onset delirium associated with isoniazid in an elderly female with spinal tuberculosis. Remarkable improvement was noticed in the patient following drug discontinuation and pyridoxine augmentation.
Address correspondence to Sankha Shubhra Chakrabarti, Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India, PIN-221005. E-mail: email@example.com
Disclaimer: No human/animal experimentation was performed. Only standard medical/surgical care was provided, and written informed consent taken from the patient’s legal guardian to publish.