Prevalence of HTLV-I Infection and Its Association with Tuberculosis among Patients at an Urban Clinic in Haiti

Kathleen F. Walsh Center for Global Health, Weill Cornell Medicine, New York, New York;
Division of General Internal Medicine, Weill Cornell Medicine, New York, New York;

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Myung Hee Lee Center for Global Health, Weill Cornell Medicine, New York, New York;

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Josef A. Brejt Division of General Internal Medicine, Weill Cornell Medicine, New York, New York;

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Mary J. Reust Center for Global Health, Weill Cornell Medicine, New York, New York;

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Marc Jean Juste GHESKIO Centers, Port-au-Prince, Haiti;

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Genevieve Hilaire GHESKIO Centers, Port-au-Prince, Haiti;

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Jean William Pape Center for Global Health, Weill Cornell Medicine, New York, New York;
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York;
GHESKIO Centers, Port-au-Prince, Haiti;

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Serena Koenig Brigham and Women’s Hospital, Boston, Massachusetts

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Kathryn Dupnik Center for Global Health, Weill Cornell Medicine, New York, New York;
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York;

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ABSTRACT.

This retrospective case–control study examined the prevalence of HTLV-I and its association with tuberculosis among urban clinic patients in Haiti. Prevalence of HTLV-I among tuberculosis cases was 2.1% and among controls was 2.4%. Prevalence of HLTV-I was higher in females than males (odds ratio [OR] 2.45, P = 0.020). HTLV-I prevalence in those ≥ 50 years was 8.4% compared with 1.3% in those < 50 (OR 6.74, P < 0.001). We found no association between HTLV-I and tuberculosis in this population.

Author Notes

Address correspondence to Kathleen F. Walsh, Center for Global Health, Weill Cornell Medicine, 402 E 67th Street, 2nd Floor, New York City, NY 10065. E-mail: kfw2001@med.cornell.edu

Financial support: This work was supported by the National Institutes of Health grants K23-AI131913 (to K. M. D.), and U19-AI111143.

Authors’ addresses: Kathleen F. Walsh, Myung Hee Lee, Josef A. Brejt, Mary J. Reust, and Kathryn Dupnik, Weill Cornell Medicine, New York, NY, E-mails: kfw2001@med.cornell.edu, myl2003@med.cornell.edu, jab9179@med.cornell.edu, juliet319@gmail.com, and kd9040@med.cornell.edu. Marc Jean Juste, Genevieve Hilaire and Jean William Pape, GHESKIO Centers, Port-au-Prince, Haiti, E-mails: mjeanjuste@gheskio.org, gehissah@gmail.com, and jwpape@gheskio.org. Serena Koenig, Brigham and Women’s Hospital, Boston, MA, E-mail: skoenig@bwh.harvard.edu.

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