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RefWorks
Reference Manager
BibTeX
Zotero
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-
1.
Mowla MR, Ara S, Tripura S , 2015. Leprosy profiles in post-elimination stage: a tertiary-care hospital experience. Int J Dermatol 54: 1407–1413.
-
2.
Maymone MBC, Laughter M, Venkatesh S, Dacso MM, Rao PN, Stryjewska BM, Hugh J, Dellavalle RP, Dunnick CA , 2020. Leprosy: clinical aspects and diagnostic techniques. J Am Acad Dermatol 83: 1–14.
-
3.
Kulkarni SK, 2016. Epidemiological profile of leprosy patients attending in a tertiary care centre in post leprosy elimination era. IOSR J Dent Med Sci 15: 1–5.
-
4.
Gupta R, Sinha R, Pradhan S , 2019. Clinico-epidemiological profile of leprosy in post elimination era: a hospital-based study. Indian J Lepr 91: 197–205.
-
5.
World Health Organization, Organisation Mondiale de la Santé , 2018. Global leprosy update, 2017: reducing the disease burden due to leprosy—situation de la lèpre dans le monde, 2017: reduction de la charge de morbidité due à la lèpre. Weekly Epidemiol Record=Relevé Épidémiologique Hebdomadaire 93: 445–456.
-
6.
Pandhi D , 2011. Childhood leprosy in a tertiary-care hospital in Delhi, India: a reappraisal in the post-elimination era. Lepr Rev 82: 259–269.
-
7.
 Ministry of Health Republic of Indonesia , 2018. Hapuskan Stigma dan Diskriminasi Terhadap Kusta. Available at: https://www.kemkes.go.id/article/view/19011500011/hapuskan-stigma-dan-diskriminasi-terhadap-kusta.html. Accessed March 2, 2020.
-
8.
Pedrosa VL, Dias LC, Galban E, Leturiondo A, Palheta J Jr. , Santos M, Moraes MO, Talhari C , 2018. Leprosy among schoolchildren in the Amazon region: a cross-sectional study of active search and possible source of infection by contact tracing. PLoS Negl Trop Dis 12: 1–12.
-
9.
Babu A, Ramesh MB, Jayaraman J , 2018. Childhood leprosy in the post-elimination era: a vision achieved or a concern growing at large. Indian J Paediatr Dermatol 19: 26.
-
10.
Oliveira MBB, Diniz LM , 2016. Leprosy among children under 15 years of age: a literature review. An Bras Dermatol 91: 196–203.
-
11.
Sarkar R, Pradhan S , 2016. Leprosy and women. Int J Womens Dermatol 2: 117–121.
-
12.
Nepomuceno Gondim Costa Lima L, LetÃcia Pinto Paz J, Siqueira Moura L, Perini Furlaneto I, Valéria Batista Lima K , 2020. BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the Brazilian amazon. Infect Dis Rep 12: 97–104.
-
13.
Lima LN, Frota CC, Mota RM, Almeida RL, Pontes MA, Gonçalves Hde S, Rodrigues LC, Kendall C, Kerr L , 2015. Widespread nasal carriage of Mycobacterium leprae among a healthy population in a hyperendemic region of northeastern Brazil. Mem Inst Oswaldo Cruz 110: 898–905.
-
14.
Mistry N, Kuruwa S, Pandya S, Minda R, Shetty V , 2016. Childhood leprosy revisited. Pediatr Oncall J 13: 83–92.
-
15.
Dogra S, Narang T, Khullar G, Kumar R, Saikia UN , 2014. Childhood leprosy through the post-leprosy-elimination era: a retrospective analysis of epidemiological and clinical characteristics of disease over eleven years from a tertiary care hospital in north India. Lepr Rev 85: 296–310.
-
16.
Relhan V, Ghunawat S, Tenani A, Mittal S, Garg V , 2016. Trends in profile of leprosy cases reporting to a tertiary care centre in Delhi during 2006–2015. Indian J Lepr 88: 217–225.
-
17.
Mushtaq S, Dogra N, Dogra D, Faizi N , 2020. Trends and patterns of leprosy over a decade in a tertiary care hospital in northern India: a retrospective analysis. Indian J Dermatol Venereol Leprol 86: 141–149.
-
18.
Darlong J, Govindharaj P, Darlong F, Mahato N , 2017. A study of untreated leprosy affected children reporting with grade 2 disability at a referral centre in West Bengal, India. Lepr Rev 88: 298–305.
-
19.
Mahajan VK , 2013. Slit-skin smear in leprosy: lest we forget it. Indian J Lepr 85: 177–183.
-
20.
Hambridge T, Nanjan Chandran SL, Geluk A, Saunderson P, Richardus JH , 2021. Mycobacterium leprae transmission characteristics during the declining stages of leprosy incidence: a systematic review. PLoS Negl Trop Dis 15: e0009436.
-
21.
 Ministry of Health Republic of Indonesia , 2018. Profil kesehatan Provinsi Jawa Timur Tahun 2017. Available at: https://dinkes.jatimprov.go.id/userimage/dokumen/PROFIL%20KESEHATAN%20JATIM%20TAHUN%202017.pdf. Accessed September 25, 2021.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 3971 | 464 | 31 |
| Full Text Views | 125 | 12 | 0 |
| PDF Downloads | 109 | 10 | 0 |
Pediatric Leprosy Profile in the Postelimination Era: A Study from Surabaya, Indonesia
Novianti Rizky Reza
Novianti Rizky Reza
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia;
Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Bagus Hario Kusumaputro
Bagus Hario Kusumaputro
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia;
Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Medhi Denisa Alinda
Medhi Denisa Alinda
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia;
Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Muhammad Yulianto Listiawan
Muhammad Yulianto Listiawan
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia;
Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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Hok Bing Thio
Hok Bing Thio
Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Cita Rosita Sigit Prakoeswa
Cita Rosita Sigit Prakoeswa
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia;
Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia;
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ABSTRACT.
Children who live in leprosy-endemic areas are susceptible to infection due to early and frequent exposure to Mycobacterium leprae. Indonesia is on the verge of eliminating this disease (prevalence rate < 1/10,000 population), but pediatric leprosy continues to occur in low-endemic areas. This study aimed to evaluate pediatric leprosy over a decade in a tertiary hospital in Surabaya, Indonesia. A retrospective study of leprosy in children under 15 years old between 2010 and 2019 was conducted in the Morbus Hansen Division, Outpatient Clinic at Dr. Soetomo Hospital in Surabaya, Indonesia. Seventy pediatric leprosy cases were identified between 2010 and 2019, consisting of 58 multibacillary (MB)-type cases and 12 paucibacillary (PB)-type cases. Slit skin smear (SSS) was positive in 26 cases. There were two cases of grade-2 disability and 15 cases of leprosy reaction (erythema nodosum leprosum) in children at the time of diagnosis. There was an insignificant decline in the number of pediatric leprosy cases in the last 10 years. Cases and disabilities in children were found in some leprosy pocket areas even though the national elimination rate has been achieved. MB infections, disability, and treatment defaults were common problems in pediatric leprosy.
Author Notes
Financial support: The author received support from the Indonesia Endowment Fund for Education (LPDP), the Ministry of Finance of the Republic of Indonesia to conduct this work. This study was also supported by Riset Mandat Grant from Airlangga University (20/RM/Thp-I/2020). The funder had no role in the study design, data collection and analysis, decision to publish, or manuscript preparation.
Authors’ addresses: Cita Rosita Sigit Prakoeswa, Medhi Denisa Alinda, Muhammad Yulianto Listiawan, and Bagus Haryo Kusumaputra, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia, and Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia, E-mails: cita-rosita@fk.unair.ac.id, medhi.denisa@fk.unair.ac.id, m.yulianto@fk.unair.ac.id, and bagushkputra@yahoo.com. Novianti Rizky Reza, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital Surabaya, Surabaya, East Java, Indonesia, Leprosy Study Group, Institute of Tropical Disease, Surabaya, Indonesia, and Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands, E-mail: novianti.rizky@fk.unair.ac.id. Hok Bing Thio, Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands, E-mail: h.thio@erasmusmc.nl.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Mowla MR, Ara S, Tripura S , 2015. Leprosy profiles in post-elimination stage: a tertiary-care hospital experience. Int J Dermatol 54: 1407–1413.
-
2.
Maymone MBC, Laughter M, Venkatesh S, Dacso MM, Rao PN, Stryjewska BM, Hugh J, Dellavalle RP, Dunnick CA , 2020. Leprosy: clinical aspects and diagnostic techniques. J Am Acad Dermatol 83: 1–14.
-
3.
Kulkarni SK, 2016. Epidemiological profile of leprosy patients attending in a tertiary care centre in post leprosy elimination era. IOSR J Dent Med Sci 15: 1–5.
-
4.
Gupta R, Sinha R, Pradhan S , 2019. Clinico-epidemiological profile of leprosy in post elimination era: a hospital-based study. Indian J Lepr 91: 197–205.
-
5.
World Health Organization, Organisation Mondiale de la Santé , 2018. Global leprosy update, 2017: reducing the disease burden due to leprosy—situation de la lèpre dans le monde, 2017: reduction de la charge de morbidité due à la lèpre. Weekly Epidemiol Record=Relevé Épidémiologique Hebdomadaire 93: 445–456.
-
6.
Pandhi D , 2011. Childhood leprosy in a tertiary-care hospital in Delhi, India: a reappraisal in the post-elimination era. Lepr Rev 82: 259–269.
-
7.
 Ministry of Health Republic of Indonesia , 2018. Hapuskan Stigma dan Diskriminasi Terhadap Kusta. Available at: https://www.kemkes.go.id/article/view/19011500011/hapuskan-stigma-dan-diskriminasi-terhadap-kusta.html. Accessed March 2, 2020.
-
8.
Pedrosa VL, Dias LC, Galban E, Leturiondo A, Palheta J Jr. , Santos M, Moraes MO, Talhari C , 2018. Leprosy among schoolchildren in the Amazon region: a cross-sectional study of active search and possible source of infection by contact tracing. PLoS Negl Trop Dis 12: 1–12.
-
9.
Babu A, Ramesh MB, Jayaraman J , 2018. Childhood leprosy in the post-elimination era: a vision achieved or a concern growing at large. Indian J Paediatr Dermatol 19: 26.
-
10.
Oliveira MBB, Diniz LM , 2016. Leprosy among children under 15 years of age: a literature review. An Bras Dermatol 91: 196–203.
-
11.
Sarkar R, Pradhan S , 2016. Leprosy and women. Int J Womens Dermatol 2: 117–121.
-
12.
Nepomuceno Gondim Costa Lima L, LetÃcia Pinto Paz J, Siqueira Moura L, Perini Furlaneto I, Valéria Batista Lima K , 2020. BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the Brazilian amazon. Infect Dis Rep 12: 97–104.
-
13.
Lima LN, Frota CC, Mota RM, Almeida RL, Pontes MA, Gonçalves Hde S, Rodrigues LC, Kendall C, Kerr L , 2015. Widespread nasal carriage of Mycobacterium leprae among a healthy population in a hyperendemic region of northeastern Brazil. Mem Inst Oswaldo Cruz 110: 898–905.
-
14.
Mistry N, Kuruwa S, Pandya S, Minda R, Shetty V , 2016. Childhood leprosy revisited. Pediatr Oncall J 13: 83–92.
-
15.
Dogra S, Narang T, Khullar G, Kumar R, Saikia UN , 2014. Childhood leprosy through the post-leprosy-elimination era: a retrospective analysis of epidemiological and clinical characteristics of disease over eleven years from a tertiary care hospital in north India. Lepr Rev 85: 296–310.
-
16.
Relhan V, Ghunawat S, Tenani A, Mittal S, Garg V , 2016. Trends in profile of leprosy cases reporting to a tertiary care centre in Delhi during 2006–2015. Indian J Lepr 88: 217–225.
-
17.
Mushtaq S, Dogra N, Dogra D, Faizi N , 2020. Trends and patterns of leprosy over a decade in a tertiary care hospital in northern India: a retrospective analysis. Indian J Dermatol Venereol Leprol 86: 141–149.
-
18.
Darlong J, Govindharaj P, Darlong F, Mahato N , 2017. A study of untreated leprosy affected children reporting with grade 2 disability at a referral centre in West Bengal, India. Lepr Rev 88: 298–305.
-
19.
Mahajan VK , 2013. Slit-skin smear in leprosy: lest we forget it. Indian J Lepr 85: 177–183.
-
20.
Hambridge T, Nanjan Chandran SL, Geluk A, Saunderson P, Richardus JH , 2021. Mycobacterium leprae transmission characteristics during the declining stages of leprosy incidence: a systematic review. PLoS Negl Trop Dis 15: e0009436.
-
21.
 Ministry of Health Republic of Indonesia , 2018. Profil kesehatan Provinsi Jawa Timur Tahun 2017. Available at: https://dinkes.jatimprov.go.id/userimage/dokumen/PROFIL%20KESEHATAN%20JATIM%20TAHUN%202017.pdf. Accessed September 25, 2021.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 3971 | 464 | 31 |
| Full Text Views | 125 | 12 | 0 |
| PDF Downloads | 109 | 10 | 0 |