Kasturiratne A, Wickremasinghe AR, de Silva N, Gunawardena NK, Pathmeswaran A, Premaratna R, Savioli L, Lalloo DG, de Silva HJ, 2008. The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med 5: e218.
World Health Organization , 2021. Snakebite Envenoming. Available at: https://www.who.int/news-room/fact-sheets/detail/snakebite-envenoming. Accessed November 26, 2020.
Potet J, Smith J, McIver L, 2019. Reviewing evidence of the clinical effectiveness of commercially available antivenoms in sub-Saharan Africa identifies the need for a multi-centre, multi-antivenom clinical trial. PLoS Negl Trop Dis 13: e0007551.
Blaylock R, 2004. Epidemiology of snakebite in Eshowe, KwaZulu-Natal, South Africa. Toxicon 43: 159–166.
Watt G, Padre L, Tuazon ML, Theakston RD, Laughlin LW, 1988. Tourniquet application after cobra bite: delay in the onset of neurotoxicity and the dangers of sudden release. Am J Trop Med Hyg 38: 618–622.
Muller G, Wium C, Modler H, Veale D, 2012. Snake bite in southern Africa: diagnosis and management. Continuing Medical Educ 30: 362–381.
Siyabona Africa, 2020 Surviving a Black Mamba Bite. Available at: http://www.krugerpark.co.za/krugerpark-times-17-black-mamba-bite-18070.html. Accessed February 4, 2020.
Parker-Cote J, Meggs WJ, 2018. First aid and pre-hospital management of venomous snakebites. Trop Med Infect Dis 3: 45.
Ahmed SM, Ahmed M, Nadeem A, Mahajan J, Choudhary A, Pal J, 2008. Emergency treatment of a snake bite: pearls from literature. J Emerg Trauma Shock 1: 97–105.
The Royal Children’s Hospital Melbourne, 2018. Snakebite. Available at: https://www.rch.org.au/clinicalguide/guideline_index/Snakebite/. Accessed November 26, 2020.
Ruha AM, Kleinschmidt KC, Greene S, Spyres MB, Brent J, Wax P, Padilla-Jones A, Campleman S, Tox IC, 2017. Snakebite Study Group. The epidemiology, clinical course, and management of snakebites in the North American Snakebite Registry. J Med Toxicol 13: 309–320.
Juckett G, Hancox JG, 2002. Venomous snakebites in the United States: management review and update. Am Fam Physician 65: 1367–1374 [erratum in: Am Fam Physician 2002 Jul 1;66(1):30].
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 7277 | 1750 | 35 |
Full Text Views | 97 | 69 | 11 |
PDF Downloads | 81 | 45 | 7 |
The black mamba is known for its notorious potent neurotoxic venom. For this reason, their bites are often erroneously treated in the field with the application of a tourniquet in the hope of delaying systemic spread of the venom. Observational studies have shown that inappropriate tourniquet application is a common, harmful practice. An arterial tourniquet is not a recommended first aid measure because of the risk of limb ischemia and gangrene. When inappropriately applied, the rapid removal of the tourniquet in the emergency department may precipitate a life-threatening venom and metabolic toxin rush, leading to respiratory arrest. We present two cases of black mamba bites in Gauteng, South Africa, where gradual tourniquet removal was used to avoid a venom rush and rapid respiratory paralysis. Venom and metabolic toxin rush with potentially fatal respiratory muscle paralysis may be averted by gradual, cautious removal of field-applied tourniquets with concomitant antivenom administration.
Authors’ addresses: Ratang Pholosho Pelle, Andreas Engelbrecht, and Vidya Lalloo, Emergency Medicine, University of Pretoria, Pretoria, South Africa, E-mails: pholoshopelle@gmail.com, dries.engelbrecht@up.ac.za, and vidya.lalloo@up.ac.za.