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Case Report: First Report of Disseminated Trachipleistophora hominis Infection in an AIDS Patient from Thailand

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  • 1 Division of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand;
  • | 2 Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;
  • | 3 Vector Biology and Vector Borne Disease Research Unit, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;
  • | 4 Department of Medical Technology, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand;
  • | 5 Research Excellence Center for Innovation and Health Products, Walailak University, Nakhon Si Thammarat, Thailand

ABSTRACT.

Microsporidial myositis caused by Trachipleistophora hominis is a life-threatening and emerging microsporidiosis among immunocompromised hosts. This article reports a case of disseminated microsporidiosis caused by T. hominis in southern Thailand. The patient had HIV and presented at the clinic with incapacitating muscle pain. She was diagnosed with disseminated microsporidiosis. Molecular identification revealed the sequence of 18S ribosomal RNA gene involving sequences sharing 99% nucleotide identity with T. hominis from an Australian patient. To our knowledge, this is the first study to report the detection of T. hominis microsporidia in an HIV patient in Thailand.

Author Notes

Address correspondence to Padet Siriyasatien, Vector Biology and Vector Borne Disease Research Unit, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330 Thailand. E-mail: padet.s@chula.ac.th

Financial support: This work was supported by the Program Management Unit for Human Resources & Institutional Development, Research, and Innovation-CU (grant no. B16F630071), and Thailand Science Research Innovation (TSRI)-CU (grant no. FRB640001).

Authors’ addresses: Pisud Siripaitoon and Thanaporn Hortiwakul, Division of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand, E-mails: spisud@medicine.psu.ac.th and hratri@medicine.psu.ac.th. Nirin Seatamanoch, Narisa Brownell, Switt Kongdachalert, and Padet Siriyasatien, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, and Vector Biology and Vector borne Disease Research Unit, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, E-mails: bownirin@gmail.com, narisa.br@chula.ac.th, switt1995@gmail.com, and padet.s@chula.ac.th. Atchara Phumee, Department of Medical Technology, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand, and Research Excellence Center for Innovation and Health Products, Walailak University, Nakhon Si Thammarat 80160, Thailand, E-mail: amphumee@gmail.com.

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