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Case Report: Progressive Dysphonia and Dysphagia due to Laryngeal Leishmaniasis

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  • 1 CHU de Tours, Service ORL et Chirurgie Cervico-Faciale, Tours, France;
  • | 2 CHU de Tours, Service de Maladies Infectieuses, Tours, France;
  • | 3 Faculté de Médecine de Tours, Université François-Rabelais de Tours, CHRU de Tours, Tours, France;
  • | 4 Service de Parasitologie, Mycologie et Médecine Tropicale. Tours, France;
  • | 5 INSERM UMR 1253 I-brain, Université François-Rabelais de Tours, CHRU de Tours, Tours, France

ABSTRACT.

Laryngeal leishmaniasis is an unusual form of the disease. We report the case of a patient who consulted for dysphonia and dysphagia in a context of asthenia and weight loss. The patient had lesions that were suggestive of laryngeal cancer but were revealed to be leishmaniasis by histopathology examination and polymerase chain reaction. Treatment with amphotericin B and miltefosine permitted complete resolution of the lesions and no recurrence during the 18-month follow-up period.

Author Notes

Address correspondence to Laura Renard, Service ORL et Chirurgie Cervico-Faciale, CHU de Tours, 2 boulevard Tonnellé, 37044 Tours, France. E-mail: laura.renard-3@etu.univ-tours.fr

Authors’ addresses: Laura Renard, CHU de Tours, Service ORL et Chirurgie Cervico-Faciale, Tours, France, E-mail: laura.renard-3@etu.univ-tours.fr. Adrien Lemaignen, CHRU Tours, ORL, Service de Maladies Infectieuses, Tours, France, E-mail: adrien.lemaignen@univ-tours.fr. Guillaume Desoubeaux, CHRU Tours, Médecine Interne et Maladies Infectieuses, Tours, France, E-mail: guillaume.desoubeaux@univ-tours.fr. David Bakhos, CHU de Tours, Service de Parasitologie - Mycologie - Médecine Tropicale, Hôpital Bretonneau, Bâtiment B2A, Tours, Indre-et-Loire, France, E-mail: david.bakhos@univ-tours.fr.

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