• 1.

    MacCallum P, Tolhurst JC, Buckle G, Sissons HA, 1948. A new mycobacterial infection in man. J Pathol Bacteriol 60: 93102.

  • 2.

    Aubry P, Gaüzère BA, 2020. Ulcère de Buruli. Available at: http://medecinetropicale.free.fr/cours/ulcere_buruli.pdf. Accessed Januray 22, 2020.

    • Search Google Scholar
    • Export Citation
  • 3.

    Zingue D, Bouam A, Tian RBD, Drancourt M, 2017. Buruli ulcer, a prototype for ecosystem-related infection, caused by Mycobacterium ulcerans. Clin Microbiol Rev 31: e00045-17.

    • Search Google Scholar
    • Export Citation
  • 4.

    George KM et al. 1999 Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. Science 283: 854857.

  • 5.

    Alcock BP et al. 2020. Card 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database. Nucleic Acids Res 48: D517D525.

    • Search Google Scholar
    • Export Citation
  • 6.

    Buultjens AH et al. 2018. Comparative genomics shows that Mycobacterium ulcerans migration and expansion preceded the rise of Buruli ulcer in southeastern Australia. Appl Environ Microbiol 84: e02612-17.

    • Search Google Scholar
    • Export Citation
  • 7.

    Portaels F et al. 2008. First cultivation and characterization of Mycobacterium ulcerans from the environment. PLoS Negl Trop Dis 2: e178.

  • 8.

    Tai AYC, Athan E, Friedman ND, Hughes A, Walton A, O’Brien DP, 2018. Increased severity and spread of Mycobacterium ulcerans, southeastern Australia. Emerg Infect Dis 24: 5864.

    • Search Google Scholar
    • Export Citation
  • 9.

    Vandelannoote K et al. 2017. Multiple introductions and recent spread of the emerging human pathogen Mycobacterium ulcerans across Africa. Genome Biol Evol 9: 414426.

    • Search Google Scholar
    • Export Citation
  • 10.

    Hammoudi N, Saad J, Drancourt M, 2020. The diversity of mycolactone-producing mycobacteria. Microb Pathog 149: 104362.

  • 11.

    Page AJ et al. 2015. Roary: rapid large-scale prokaryote pan genome analysis. Bioinformatics 31: 36913693.

Past two years Past Year Past 30 Days
Abstract Views 647 187 0
Full Text Views 251 149 27
PDF Downloads 152 77 14
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

 

 

 

Case Report: A New Mycobacterium ulcerans Genotype Causing Buruli Ulcer in Côte d’Ivoire

Philippe BahadoranDepartment of Dermatology, Centre Hospitalier Universitaire de Nice, Université Côte D’Azur, Inserm, Nice, France;

Search for other papers by Philippe Bahadoran in
Current site
Google Scholar
PubMed
Close
,
Nassim HammoudiIRD, MEPHI, IHU Méditerranée Infection, Aix-Marseille-Université, Marseille, France;
IHU Méditerranée Infection, Marseille, France;

Search for other papers by Nassim Hammoudi in
Current site
Google Scholar
PubMed
Close
,
Alice GaudartLaboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Hôpital de l’Archet II, Nice, France;

Search for other papers by Alice Gaudart in
Current site
Google Scholar
PubMed
Close
,
Jamal SaadIRD, MEPHI, IHU Méditerranée Infection, Aix-Marseille-Université, Marseille, France;
IHU Méditerranée Infection, Marseille, France;

Search for other papers by Jamal Saad in
Current site
Google Scholar
PubMed
Close
,
Yoan Di FilippoDepartment of Dermatology, Centre Hospitalier Universitaire de Nice, Université Côte D’Azur, Inserm, Nice, France;

Search for other papers by Yoan Di Filippo in
Current site
Google Scholar
PubMed
Close
,
Michel DrancourtIRD, MEPHI, IHU Méditerranée Infection, Aix-Marseille-Université, Marseille, France;
IHU Méditerranée Infection, Marseille, France;

Search for other papers by Michel Drancourt in
Current site
Google Scholar
PubMed
Close
, and
Raymond RuimyLaboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Hôpital de l’Archet II, Nice, France;
Université Côte D’Azur, Inserm, C3M, Nice, France;
Inserm U1065, C3M, Equipe 6, Nice, France

Search for other papers by Raymond Ruimy in
Current site
Google Scholar
PubMed
Close
Restricted access

ABSTRACT

Mycobacterium ulcerans, the opportunistic pathogen causing Buruli ulcer, is reported to affect rural populations in 36 tropical countries. We report one case of Buruli ulcer in a peri-urban area in Côte d’Ivoire, confirmed by whole genome sequencing which indicated a M. ulcerans genotype previously unreported in Côte d’Ivoire.

    • Supplemental Materials (XLSX 84.79 KB)
    • Supplemental Materials (PPT 1.52 MB)

Author Notes

Address correspondence to Raymond Ruimy, Laboratoire de Bacteriologie, 151, Route de St Antoine de Ginestière, Nice 06000, France. E-mail: ruimy.r@chu-nice.fr

Financial support: N. H. obtained a PhD grant from the Fondation Méditerranée Infection, Marseille, France. This work was supported by the Agence Nationale de la Recherche (ANR-17-CE35-0006-01 PRIME, http://www.agencenationale-recherche.fr/) and by the French government under the “Investissements d’Avenir” (Investments in the Future) program managed by the A. N. R. (reference: Méditerranée Infection 10-IAHU-03). This work was supported by Région Le Sud (Provence Alpes Côte d’Azur) and European FEDER IHUBIOTK funding.

Authors’ addresses: Philippe Bahadoran and Yoan Di Filippo, Centre Hospitalier Universitaire de Nice, Dermatology, Nice, Provence-Alpes-Côte d'Azur, France, E-mails: bahadoran.P@chu-nice.fr and difilippo.y@chu-nice.fr. Nassim Hammoudi, Jamal Saad, and Michel Drancourt, Aix-Marseille Universite, MEPHI, Marseille, Provence-Alpes-Côte d'Azu, France, E-mails: nassimveto15@live.fr, jsaad270@gmail.com, and michel.drancourt@univ-amu.fr. Alice Gaudart, Laboratoire de Bactériologie, Centre Hospitalier, Universitaire de Nice, Hôpital de l'Archet II, Nice, France, E-mail: gaudart.a@chu-nice.fr. Raymond Ruimy, Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Hôpital de l'Archet II, Laboratoire de Bacteriologie, 151, Route de St Antoine de Ginestière, Nice, France, and Inserm, C3M, Team 6, Nice, France, E-mail: ruimy.r@chu-nice.fr.

Save