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Case Report: A New Mycobacterium ulcerans Genotype Causing Buruli Ulcer in Côte d’Ivoire

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  • 1 Department of Dermatology, Centre Hospitalier Universitaire de Nice, Université Côte D’Azur, Inserm, Nice, France;
  • | 2 IRD, MEPHI, IHU Méditerranée Infection, Aix-Marseille-Université, Marseille, France;
  • | 3 IHU Méditerranée Infection, Marseille, France;
  • | 4 Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Hôpital de l’Archet II, Nice, France;
  • | 5 Université Côte D’Azur, Inserm, C3M, Nice, France;
  • | 6 Inserm U1065, C3M, Equipe 6, Nice, France

ABSTRACT

Mycobacterium ulcerans, the opportunistic pathogen causing Buruli ulcer, is reported to affect rural populations in 36 tropical countries. We report one case of Buruli ulcer in a peri-urban area in Côte d’Ivoire, confirmed by whole genome sequencing which indicated a M. ulcerans genotype previously unreported in Côte d’Ivoire.

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Author Notes

Address correspondence to Raymond Ruimy, Laboratoire de Bacteriologie, 151, Route de St Antoine de Ginestière, Nice 06000, France. E-mail: ruimy.r@chu-nice.fr

Financial support: N. H. obtained a PhD grant from the Fondation Méditerranée Infection, Marseille, France. This work was supported by the Agence Nationale de la Recherche (ANR-17-CE35-0006-01 PRIME, http://www.agencenationale-recherche.fr/) and by the French government under the “Investissements d’Avenir” (Investments in the Future) program managed by the A. N. R. (reference: Méditerranée Infection 10-IAHU-03). This work was supported by Région Le Sud (Provence Alpes Côte d’Azur) and European FEDER IHUBIOTK funding.

Authors’ addresses: Philippe Bahadoran and Yoan Di Filippo, Centre Hospitalier Universitaire de Nice, Dermatology, Nice, Provence-Alpes-Côte d'Azur, France, E-mails: bahadoran.P@chu-nice.fr and difilippo.y@chu-nice.fr. Nassim Hammoudi, Jamal Saad, and Michel Drancourt, Aix-Marseille Universite, MEPHI, Marseille, Provence-Alpes-Côte d'Azu, France, E-mails: nassimveto15@live.fr, jsaad270@gmail.com, and michel.drancourt@univ-amu.fr. Alice Gaudart, Laboratoire de Bactériologie, Centre Hospitalier, Universitaire de Nice, Hôpital de l'Archet II, Nice, France, E-mail: gaudart.a@chu-nice.fr. Raymond Ruimy, Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Hôpital de l'Archet II, Laboratoire de Bacteriologie, 151, Route de St Antoine de Ginestière, Nice, France, and Inserm, C3M, Team 6, Nice, France, E-mail: ruimy.r@chu-nice.fr.

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