• 1.

    Deng K, Cui J, Qin Y, Zhu Y, Feng G, 2019. First report of sparganosis manifested by pleuritis and decreased peripheral blood eosinophils in Jiangsu province, China. Parasitol Res 118: 16531656.

    • Search Google Scholar
    • Export Citation
  • 2.

    Lu G, Shi DZ, Lu YJ, Wu LX, Li LH, Rao LY, Yin FF, 2014. Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012. Epidemiol Infect 142: 26542661.

    • Search Google Scholar
    • Export Citation
  • 3.

    Zhang X, Duan JY, Shi YL, Jiang P, Zeng J, Wang ZQ, Cui J, 2017. Comparative mitochondrial genomics among Spirometra (Cestoda: Diphyllobothriidae) and the molecular phylogeny of related tapeworms. Mol Phylogenet Evol 117: 7582.

    • Search Google Scholar
    • Export Citation
  • 4.

    Hong Q et al. 2016. Prevalence of Spirometra mansoni in dogs, cats, and frogs and its medical relevance in Guangzhou, China. Int J Infect Dis 53: 4145.

    • Search Google Scholar
    • Export Citation
  • 5.

    Zhang X, Cui J, Liu LN, Jiang P, Wang H, Qi X, Wu XQ, Wang ZQ, 2015. Genetic structure analysis of Spirometra erinaceieuropaei isolates from central and southern China. PLoS One 10: e0119295.

    • Search Google Scholar
    • Export Citation
  • 6.

    Xie D, Wang M, Chen X, Tuo HZ, 2019. A case report: 1-year follow-up of cerebral sparganosis mansoni with a stroke-like onset. BMC Neurol 19: 105.

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Case Report: Morphologic and Genetic Identification of Cerebral Sparganosis

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  • 1 Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;
  • | 2 Department of Parasitology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, China;
  • | 3 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China
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A 50-year-old Chinese woman with a history of weakness and paroxysmal seizures of the left limb presented to our hospital with a ten-day history of neck pain. Imaging showed that there was a mass in the frontal lobe of her brain. On resection of the mass, a motile worm was identified. Morphological observation and molecular analysis of the mitochondrial COX1 and 28S rRNA genes of the worm extracted from the brain identified the causative agent as Spirometra mansoni. Homology search of the polymerase chain reaction (PCR)-amplified products from the case was conducted against gene fragments from local wild frogs. High homology was found between them, showing her likely exposure was frog consumption.

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Author Notes

Address correspondence to Ying Ma, Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China, E-mail: majiying72@hotmail.com or Xiang Wang, Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China, 610000, E-mail: wangxiangtim@gmail.com.

Authors’ addresses: Yanming Meng, Ziwei Kuang, and Ying Ma, Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China, E-mails: 25983619@qq.com, kuangzw1214@163.com, and majiying72@hotmail.com. Lin Liao, Department of Parasitology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, China, E-mail: liaolin08@126.com. Xiang Wang, Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China, E-mail: wangxiangtim@gmail.com.

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