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Case Report: Two Cases of Strongyloidiasis Presenting with Thrombotic Events

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  • 1 Department of Medicine, University of Toronto, Toronto, Canada;
  • | 2 St. Joseph’s Health Centre, Toronto, Canada;
  • | 3 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;
  • | 4 Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada;
  • | 5 Department of Medicine, McMaster University, Hamilton, Canada;
  • | 6 Tropical Disease Unit, Toronto General Hospital, Toronto, Canada
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We report two unusual cases of clinical strongyloidiasis that present as extensive thrombosis: a case of hyperinfection with concurrent eosinophilia and a case of disseminated infection as a complication of immunosuppression. We discuss risk factors for the development of Strongyloides stercoralis infection and thromboembolism, and the recommended management.

Author Notes

Address correspondence to Mara Waters, Department of Medicine, University of Toronto, Toronto, Canada, M5G 2C4. E-mail: mara.waters@mail.utoronto.ca

Financial support: J. K. reports personal fees from Merck Frosst and Pfizer outside the submitted work. M. C. reports grants and other from Bayer; personal fees from Shionogi, Alexion, Pfizer, Octapharma, BMS Canada, CSL Behring, Servier Canada, Diagnostica Stago, and Asahi Kasei; grants from Leo Pharma and Heart and Stroke Foundation; and other from Daiichi and Alnylam, outside the submitted work.

Authors’ addresses: Mara Waters, Department of Medicine, University of Toronto, Toronto, Canada, E-mail: mara.waters@mail.utoronto.ca. Sigmund Krajden, Christie Kim, Reem Elsobky, and Bohdan Lychacz, St. Joseph’s Health Centre, Toronto, Canada, E-mails: skrajden@stjoestoronto.ca, ckim@stjoestoronto.ca, relsobky@stjoestoronto.ca, and blychacz@stjoestoronto.ca. Matthew Cheung, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada, E-mail: matthew.cheung@sunnybrook.ca. Mark Crowther, Department of Medicine, McMaster University, Hamilton, Canada, E-mail: crowthrm@mcmaster.ca. Jay Keystone, Tropical Disease Unit, Toronto General Hospital, Toronto, Canada, E-mail: jay.keystone@utoronto.ca.

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