Case Report: Subacute Sclerosing Panencephalitis Presenting as Acute Encephalitis

Ravindra Kumar Garg Department of Neurology, King George’s Medical University, Lucknow, India;

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Neeraj Kumar Department of Neurology, King George’s Medical University, Lucknow, India;

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Imran Rizvi Department of Neurology, King George’s Medical University, Lucknow, India;

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Amita Jain Department of Microbiology, King George’s Medical University, Lucknow, India

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Ravi Shekhar Jaipuriar Department of Neurology, King George’s Medical University, Lucknow, India;

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Praveen Kumar Sharma Department of Neurology, King George’s Medical University, Lucknow, India;

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Hardeep Singh Malhotra Department of Neurology, King George’s Medical University, Lucknow, India;

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Danish Nasar Khan Department of Microbiology, King George’s Medical University, Lucknow, India

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Ravi Uniyal Department of Neurology, King George’s Medical University, Lucknow, India;

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Subacute sclerosing panencephalitis (SSPE) is still a common disease in India which is characterized by a progressive mental decline, myoclonus, periodic encephalographic abnormalities, and raised anti-measles antibody titter in the cerebrospinal fluid. Acute fulminant SSPE is characterized by a rapid course of disease culminating in death, within 6 months. We report of a 10-year-old boy, who came with a 14-day history of continuous involuntary jerky movements of the left half of the body, including the head. There was a highly increased anti-measles IgG antibody titer, both in the cerebrospinal fluid and serum. We conclude that acute rapidly progressive SSPE can present as acute encephalitis syndrome.

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Author Notes

Address correspondence to Ravindra Kumar Garg, Department of Neurology, King George’s Medical University, Lucknow 226003, India. E-mail: garg50@yahoo.com

Disclosure: The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and specific efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Authors’ addresses: Ravindra Kumar Garg and Hardeep Singh Malhotra, Department of Neurology, King George’s Medical University, Lucknow, India, E-mails: garg50@yahoo.com and drhsmalhotra@gmail.com. Neeraj Kumar, Imran Rizvi, Ravi Shekhar Jaipuriar, Praveen Kumar Sharma, and Ravi Uniyal, Department of Neurology, King George’s Medical University, Lucknow, India, E-mails: drneeraj2903@gmail.com, imranrizvi09@gmail.com, jaipuriarshekhar@gmail.com, pspgimer@gmail.com, and ravi.sun.uniyal@gmail.com. Amita Jain and Danish Nasar Khan, Department of Microbiology, King George’s Medical University, Lucknow, India, E-mails: amita602002@yahoo.com and microbiology@kgmcindia.edu.

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