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Hepatitis E virus (HEV) infection is associated with a high fatality rate among pregnant women, and gestational complications have been reported among pregnant women infected with hepatitis A virus (HAV). The aim of this study was to determine the seroprevalence of HAV and HEV infections among pregnant women in Haiti. We stratified the population (n = 1,307) between West and non-West regions. Specimens were tested for total HAV antibody (anti-HAV), and IgM and IgG HEV antibody (anti-HEV). Overall, 96.8% pregnant women were positive for total anti-HAV, 10.3% for IgG anti-HEV, and 0.3% for IgM anti-HEV. The prevalence of IgG anti-HEV in the non-West region (12.3%) was significantly greater than that in the West region (5.3%) (P < 0.0001). Most pregnant women in Haiti had evidence of past exposure and immunity to HAV. The non-West region had a higher prevalence of HEV. Improvement in water and sanitation will help in the prevention and control of these infections in Haiti.
Address correspondence to Alexandra Tejada-Strop, US Centers for Disease Control and Prevention, MS-A33, 1600 Clifton Rd. NE, Atlanta, GA 30329. E-mail: firstname.lastname@example.org
Authors’ addresses: Alexandra Tejada-Strop, Rania A. Tohme, Xin Ji, and Saleem Kamili, US Centers for Disease Control and Prevention, Atlanta, GA, E-mails: email@example.com, firstname.lastname@example.org, email@example.com, and firstname.lastname@example.org. Jocelyne Andre-Alboth and Jacques Boncy, National Public Health Laboratory, Ministry of Public Health and Population, Port-au-Prince, Haiti, E-mails: email@example.com and firstname.lastname@example.org. Lana Childs, Oak Ridge Institute for Science and Education, Centers for Disease Control and Prevention, Atlanta, GA and US Centers for Disease Control and Prevention, Atlanta, GA, E-mail: email@example.com. Vivianne de Oliveira Landgraf de Castro, Federal University of Mato Grosso do Sul, Campo Grande, Brazil, E-mail: firstname.lastname@example.org.
Disclosure: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC.