Epidemiological Characteristics and Spatial Analysis of Tick-Borne Encephalitis in Jilin Province, China

Qinglong Zhao Jilin Provincial Center for Disease Control and Prevention, Changchun, China;

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Xinlou Li Center for Disease Control and Prevention of Aerospace System, Beijing, China;
PLA Strategic Support Force Characteristic Medical Center, Beijing, China;
State Key Laboratory of Resources and Environmental Information System, Chinese Academy of Sciences, Beijing, China;

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Wenyi Zhang Chinese PLA Center for Disease Control and Prevention, Beijing, China;

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Chenyi Chu Chinese PLA Center for Disease Control and Prevention, Beijing, China;

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Laishun Yao Jilin Provincial Center for Disease Control and Prevention, Changchun, China;

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Yang Zhang Jilin Provincial Center for Disease Control and Prevention, Changchun, China;

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Quan Qian Chinese PLA Center for Disease Control and Prevention, Beijing, China;

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Meina Li The First Hospital of Jilin University, Changchun, China

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Shenlong Li Chinese PLA Center for Disease Control and Prevention, Beijing, China;

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Na Li Center for Disease Control and Prevention of Aerospace System, Beijing, China;
PLA Strategic Support Force Characteristic Medical Center, Beijing, China;

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Xiaobo Zhao PLA Strategic Support Force Characteristic Medical Center, Beijing, China;

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Haifeng Song PLA Strategic Support Force Characteristic Medical Center, Beijing, China;

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Yong Wang Chinese PLA Center for Disease Control and Prevention, Beijing, China;

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Biao Huang Jilin Provincial Center for Disease Control and Prevention, Changchun, China;

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Tick-borne encephalitis (TBE) is a viral infectious disease and has become a reemerging public health threat in recent years in northeastern China. However, no studies has characterized the epidemiologic features and explored the spatial dynamics and environmental factors of TBE cases in Jilin Province. In this study, we have described the epidemiological features of 846 reported human TBE cases from 2006 to 2016 in Jilin Province. There was an obvious single peak pattern of TBE cases from May to July in Jilin Province. More than 60% of TBE cases occurred in farmers, and the people in 50- to 59-year-old group had the high incidence of the disease. The results of Getis-Ord Gi* statistics demonstrated that the human TBE cases were more clustered in the northeastern border including Dunhua and Yanji cities and Antu and Wangqing counties, and southern areas including Huinan, Jingyu, Jiangyuan, and Liuhe counties in Jilin Province. We demonstrated that the temporal dynamics of TBE in Jilin was significantly associated with the dynamics of meteorological factors especially after 2009. The results from the auto-logistic regression analysis showed that the percentage coverage of forest, temperature, and autoregressive term were significantly associated with the occurrence of human TBE cases in Jilin Province. Our findings will provide a scientific evidence for the targeted prevention and control programs.

Author Notes

Address correspondence to Yong Wang, Chinese PLA Center for Disease Control and Prevention, 20 Dong-Da St., Fengtai District, Beijing 100071, China, E-mail: ywang7508@sina.com or Biao Huang, Jilin Provincial Center for Disease Control and Prevention, Changchun 130062, China, E-mail: huangbiao2000@sohu.com.

Authors’ addresses: Qinglong Zhao, Laishun Yao, Yang Zhang, and Biao Huang, Jilin Provincial Center for Disease Control and Prevention, Changchun, China, E-mails: jlcdczql@126.com, yls@jlcdc.com.cn, zyjlcdc@163.com, and huangbiao2000@sohu.com. Xinlou Li, Center for Disease Control and Prevention of Aerospace System, Beijing, China, PLA Strategic Support Force Characteristic Medical Center, Beijing, China, and State Key Laboratory of Resources and Environmental Information System, Chinese Academy of Sciences, Beijing, China, E-mail: xinlou2010@163.com. Wenyi Zhang, Chenyi Chu, Quan Qian, Shenlong Li, and Yong Wang, Chinese PLA Center for Disease Control and Prevention, Beijing, China, E-mails: zwy0419@126.com, cychu33@126.com, qianquan@aliyun.com, lishenlong@sohu.com, and ywang7508@sina.com. Xiaobo Zhao and Haifeng Song, PLA Strategic Support Force Characteristic Medical Center, Beijing, China, E-mails: 785728956@qq.com and 15810666623@163.com. Meina Li, The First Hospital of Jilin University, Changchun, China, E-mail: lmn_1982@yeah.net. Na Li, Center for Disease Control and Prevention of Aerospace System, Beijing, China, and PLA Strategic Support Force Characteristic Medical Center, Beijing, China, E-mail: gw_lina@126.com.

These authors contributed equally to this work.

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