Transmission of the M Strain of Plasmodium cynomolgi to Man

G. Robert Coatney
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Harvey A. Elder
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Peter G. Contacos
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Morton E. Getz
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Robert Greenland
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Richard N. Rossan
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L. H. Schmidt
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DOI:
https://doi.org/10.4269/ajtmh.1961.10.673
Volume/Issue:
Volume 10: Issue 5
Page(s):
673–678
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Summary

Attempts to transmit the classical M strain of Plasmodium cynomolgi to man via mosquito resulted in a low-grade infection in only one (a Caucasian) of eleven volunteers, two Negroes and nine whites.

Subsequent passage of this strain through human volunteers increased its capacity to produce infections and clinical manifestations.

Residence in the human subject did not alter the capacity of the strain to produce characteristic M-type infections in the rhesus monkey.

Author Notes

Present address: University of Miami School of Medicine, Jackson Memorial Hospital, Miami 36, Florida.

Copyright:
Copyright © 1961 by The American Society of Tropical Medicine and Hygiene 1961
Published Online:
Sep 1961
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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