Resistance of Plasmodium Falciparum to Pyrimethamine and Proguanil in Netherlands New Guinea

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  • Department of Public Health, Division of Malariology, Hollandia, New Guinea, Netherlands


Three months after the initiation of a test project wherein pyrimethaminised salt was distributed among the population in a holoendemic malaria region in Netherlands New Guinea, Plasmodium falciparum appeared to have developed resistance to pyrimethamine. This strain also was found to be cross-resistant to proguanil (Paludrine®).