By H. J. Bensted, W. Bulloch, L. Dudgeon, A. G. Gardner, E. D. W. Greig, D. Harvey, W. F. Harvey, T. J. Mackie, R. A. O'Brien, H. M. Perry, H. Scutze, P. Bruce White, W. J. Wilson. London, 1929. His Majesty's Stationery Office. Pp. 1–482
by A. Trevor Willis, M.D., B.S. (Melb.), Ph.D. (Leeds), M.C.Path., M.C.P.A., Reader in Microbiology, Monash University, formerly Lecturer in Bacteriology, University of Leeds. xiv + 234 pages, illustrated, second edition. Butterworth Inc., Washington. 1965. $8.50
For semi-immune Africans reared in districts of malarial holoendemicity in East Africa, the following single doses of chloroquine phosphate (recorded as base) are effective in the treatment of malaria caused by any species of parasite and appear to achieve radical cure of subtertian malaria: age 0 to 1 year, 19 mg; 1 to 2 years, 37 mg; 3 to 5 years, 75 mg; and 6 years and older, 120 mg. For suppression, the respective dosages are 19 mg, 37 mg, 75 mg, and 75 mg.
The doses used for treatment clear parasitemia, fever and symptoms attributable to malaria as quickly as do larger doses and stimulate less vomiting. They should precede courses of suppressive treatment.