By Everard L. Napier, M.R.C.S., L.R.C.P. (Lond.). In charge Kala-azar research, Calcutta School of Tropical Medicine. Second edition. 185 pages of text with 15 charts in the text, 18 plates, and an appendix of references to literature, author index and subject index. Oxford University Press. London, Bombay, Calcutta, Madras, 1927
Complement fixation tests were performed on 2592 individuals in a general hospital using a commercially prepared Endamoeba histolytica antigen. Positive reactions were obtained with the sera from 86 per cent of the cases of extraintestinal amebiasis, 15 per cent of the cases of intestinal amebiasis only and 0.7 per cent of the cases that had equivocal or no evidence of amebiasis.
The type of antigen employed is of especial value, therefore, in drawing attention to the possible presence of E. histolytica infections other than intestinal and as an aid in the differential diagnosis of hepatic and pulmonary conditions.