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Adaptation of Dengue Virus to the Hamster
Summary
By serial intracerebral passages, the New Guinea C and Hawaiian strains of dengue virus were adapted to growth in hamsters of 2–5 days of age.
Dengue virus should no longer be described, without qualification, as non-pathogenic for the hamster.
Additional data are presented showing that the New Guinea C and Hawaiian strains represent 2 different immunologic types of dengue virus.
Author Notes
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