Volume 88, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We describe the diagnostic difficulties experienced during an opisthorchiasis outbreak. Of 31 infected individuals, 61.3% were asymptomatic, and in the 12 symptomatic individuals, the duration of non-pathognomonic symptoms was shorter than 4 weeks. Serology by enzyme-linked immunosorbent assay and polymerase chain reaction fecal analysis were shown to be the most sensitive diagnostic tools.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ, , 2011. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop 120: S158S168.[Crossref] [Google Scholar]
  2. Erhardt A, Germer WD, Hörning B, , 1962. Die Opisthorchiasis, hervorgerufen durch den Katzenleberegel Opisthorchis felineus (Riv.). Parasitologische Schriftenreihe 15. Jena, Germany: Veb Gustav Fischer Verlag, 1170. [Google Scholar]
  3. Sänger R, Möller FW, Lafrenz M, Ziegler K, , 1991. An endemic focus of Opisthorchis felineus in Mecklenburg-Pommerania/Germany. Trop Med Parasitol 42: 463. [Google Scholar]
  4. Hering-Hagenbeck S, Schuster R, , 1996. A focus of opisthorchiidosis in Germany. Appl Parasitol 37: 260265. [Google Scholar]
  5. Armignacco O, Caterini L, Marucci G, Ferri F, Bernardini G, Natalini Raponi G, Ludovisi A, Bossù T, Gomez Morales MA, Pozio E, , 2008. Human illnesses caused by Opisthorchis felineus flukes, Italy. Em Infect Dis 14: 19021905.[Crossref] [Google Scholar]
  6. Schuster RK, , 2010. Opisthorchiidosis—a review. Infect Disord Drug Targets 10: 402415.[Crossref] [Google Scholar]
  7. Mordinov VA, Furman DP, , 2010. The Digenea parasite Opisthorchis felineus: a target for the discovery and development of novel drugs. Infect Disord Drug Targets 10: 385401.[Crossref] [Google Scholar]
  8. Traverso A, Repetto E, Magnani S, Meloni T, Natrella M, Marchisio P, Giacomazzi C, Bernardi P, Gatti S, Gomez Morales MA, Pozio E, , 2012. A large outbreak of Opisthorchis felineus in Italy suggests that opisthorchiasis develops as a febrile eosinophilic syndrome with cholestasis rather than a hepatitis-like syndrome. Eur J Clin Microbiol Infect Dis 31: 10891093.[Crossref] [Google Scholar]
  9. Müller B, Schmidt J, Mehlhorn H, , 2007. PCR diagnosis of infections with different species of opisthorchiidae using a rapid clean-up procedure for stool samples and specific primers. Parasitol Res 100: 905909.[Crossref] [Google Scholar]
  10. Crotti D, D'Annibale ML, Crotti S, , 2007. Opistorchiasi autoctona del Lago Trasimeno (Perugia): descrizione di due episodi epidemici da Opisthorchis felineus e problematiche diagnostiche differenziali. Microbiologia Medica 42: 3641. [Google Scholar]
  11. Lvova MN, Tangkawattana S, Balthaisong S, Katokhin AV, Mordvinov VA, Sripa B, , 2012. Comparative histopathology of Opisthorchis felineus and Opisthorchis viverrini in a hamster model: an implication of high pathogenicity of the European liver fluke. Parasitol Int 61: 167172.[Crossref] [Google Scholar]
  12. Mordvinov VA, Yurlova NI, Ogorodova LM, Katokhin AV, , 2012. Opisthorchis felineus and Metorchis bilis are the main agents of liver fluke infection of humans in Russia. Parasitol Int 61: 2531.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 04 May 2012
  • Accepted : 16 Sep 2012
  • Published online : 06 Feb 2013

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error