1921
Volume 88, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Malaria has been a heavy social and health burden in the remote and poor areas in southern China. Analyses of malaria epidemic patterns can uncover important features of malaria transmission. This study identified spatial clusters, seasonal patterns, and geographic variations of malaria deaths at a county level in Yunnan, China, during 1991–2010. A discrete Poisson model was used to identify purely spatial clusters of malaria deaths. Logistic regression analysis was performed to detect changes in geographic patterns. The results show that malaria mortality had declined in Yunnan over the study period and the most likely spatial clusters (relative risk [RR] = 23.03–32.06, < 0.001) of malaria deaths were identified in western Yunnan along the China–Myanmar border. The highest risk of malaria deaths occurred in autumn (RR = 58.91, < 0.001) and summer (RR = 31.91, < 0.001). The results suggested that the geographic distribution of malaria deaths was significantly changed with longitude, which indicated there was decreased mortality of malaria in eastern areas over the last two decades, although there was no significant change in latitude during the same period. Public health interventions should target populations in western Yunnan along border areas, especially focusing on floating populations crossing international borders.

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References

  1. World Health Organization, 2010. Global Malaria Programme: World Malaria Report. Geneva: World Health Organization. [Google Scholar]
  2. Rodriguez-Morales AJ, Benítez JA, Arria M, , 2008. Malaria mortality in Venezuela: focus on deaths due to Plasmodium vivax in children. J Trop Pediatr 54: 94101.[Crossref] [Google Scholar]
  3. Hui FM, Xu B, Chen ZW, Cheng X, Liang L, Huang HB, Fang LQ, Yang H, Zhou HN, Yang HL, , 2009. Spatio-temporal distribution of malaria in Yunnan Province, China. Am J Trop Med Hyg 81: 503509. [Google Scholar]
  4. Clements A, Barnett AG, Cheng ZW, Snow RW, Zhou HN, , 2009. Space-time variation of malaria incidence in Yunnan province, China. Malar J 8: 180.[Crossref] [Google Scholar]
  5. Zhang WY, Wang LP, Fang LQ, Ma JQ, Xu YF, Jiang YF, Hui FM, Wang JJ, Liang S, Yang H, Cao WC, , 2008. Spatial analysis of malaria in Anhui province, China. Malar J 7: 206.[Crossref] [Google Scholar]
  6. Zhou SS, Wang Y, Fang W, Tang LH, , 2008. Malaria situation in the People's Republic of China in 2007. Chin J Parasitol Parasit Dis 25: 401403. [Google Scholar]
  7. Xu JW, Liu H, , 1997. Border malaria in Yunnan, China. Southeast Asian J Trop Med Public Health 28: 456459. [Google Scholar]
  8. Craig M, Kleinschmidt I, Le Sueur D, Sharp B, , 2004. Exploring 30 years of malaria case data in KwaZulu-Natal, South Africa: Part II. The impact of non-climatic factors. Trop Med Int Health 9: 12581266.[Crossref] [Google Scholar]
  9. Craig M, Kleinschmidt I, Nawn J, Le Sueur D, Sharp B, , 2004. Exploring 30 years of malaria case data in KwaZulu-Natal, South Africa: Part I. The impact of climatic factors. Trop Med Int Health 9: 12471257.[Crossref] [Google Scholar]
  10. Githeko AK, Lindsay SW, Confalonieri UE, Patz JA, , 2000. Climate change and vector-borne diseases: a regional analysis. Bull World Health Organ 78: 11361147. [Google Scholar]
  11. Lindsay S, Martens W, , 1998. Malaria in the African highlands: past, present and future. Bull World Health Organ 76: 33. [Google Scholar]
  12. Zhou XN, Lv S, Yang GJ, Kristensen TK, Bergquist NR, Utzinger J, Malone JB, , 2009. Spatial epidemiology in zoonotic parasitic diseases: insights gained at the 1st International Symposium on Geospatial Health in Lijiang, China, 2007. Parasit Vectors 2: 10.[Crossref] [Google Scholar]
  13. Clarke KC, McLafferty SL, Tempalski BJ, , 1996. On epidemiology and geographic information systems: a review and discussion of future directions. Emerg Infect Dis 2: 85.[Crossref] [Google Scholar]
  14. Brooker S, Clarke S, Njagi JK, Polack S, Mugo B, Estambale B, Muchiri E, Magnussen P, Cox J, , 2004. Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western Kenya. Trop Med Int Health 9: 757766.[Crossref] [Google Scholar]
  15. Craig M, Snow R, Le Sueur D, , 1999. A climate-based distribution model of malaria transmission in sub-Saharan Africa. Parasitol Today 15: 105110.[Crossref] [Google Scholar]
  16. Hay SI, Snow RW, Rogers DJ, , 1998. Predicting malaria seasons in Kenya using multitemporal meteorological satellite sensor data. Trans R Soc Trop Med Hyg 92: 1220.[Crossref] [Google Scholar]
  17. Tanser FC, Sharp B, le Sueur D, , 2003. Potential effect of climate change on malaria transmission in Africa. Lancet 362: 17921798.[Crossref] [Google Scholar]
  18. Snow RW, Craig M, Deichmann U, Marsh K, , 1999. Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population. Bull World Health Organ 77: 624640. [Google Scholar]
  19. Beck LR, Rodriguez MH, Dister SW, Rodriguez AD, Rejmankova E, Ulloa A, Meza RA, Roberts DR, Paris JF, Spanner MA, , 1994. Remote sensing as a landscape epidemiologic tool to identify villages at high risk for malaria transmission. Am J Trop Med Hyg 51: 271. [Google Scholar]
  20. Ernst KC, Adoka SO, Kowuor DO, Wilson ML, John CC, , 2006. Malaria hotspot areas in a highland Kenya site are consistent in epidemic and non-epidemic years and are associated with ecological factors. Malar J 5: 78.[Crossref] [Google Scholar]
  21. Srivastava A, Nagpal B, Joshi P, Paliwal J, Dash A, , 2009. Identification of malaria hot spots for focused intervention in tribal state of India: a GIS based approach. Int J Health Geogr 8: 30.[Crossref] [Google Scholar]
  22. Kulldorff M, , 1997. A spatial scan statistic. Comm Statist Theory Methods 26: 14811496.[Crossref] [Google Scholar]
  23. Mostashari F, Kulldorff M, Hartman JJ, Miller JR, Kulasekera V, , 2003. Dead bird clusters as an early warning system for West Nile virus activity. Emerg Infect Dis 9: 641.[Crossref] [Google Scholar]
  24. Zhang Z, Carpenter TE, Chen Y, Clark AB, Lynn HS, Peng W, Zhou Y, Zhao G, Jiang Q, , 2008. Identifying high-risk regions for schistosomiasis in Guichi, China: a spatial analysis. Acta Trop 107: 217223.[Crossref] [Google Scholar]
  25. Morrison AC, Getis A, Santiago M, Rigau-Perez JG, Reiter P, , 1998. Exploratory space-time analysis of reported dengue cases during an outbreak in Florida, Puerto Rico, 1991–1992. Am J Trop Med Hyg 58: 287298. [Google Scholar]
  26. Naish S, Hu W, Mengersen K, Tong S, , 2011. Spatial and temporal clusters of Barmah Forest virus disease in Queensland, Australia. Trop Med Int Health 16: 884893.[Crossref] [Google Scholar]
  27. Coleman M, Mabuza A, Kok G, Coetzee M, Durrheim D, , 2009. Using the SaTScan method to detect local malaria clusters for guiding malaria control programmes. Malar J 8: 68.[Crossref] [Google Scholar]
  28. Asnakew Y, Sucharita G, Afework H, Dereje D, Hrishikesh P, , 2009. Spatial analysis of malaria incidence at the village level in areas with unstable transmission in Ethiopia. Int J Health Geogr 8: 5.[Crossref] [Google Scholar]
  29. Zhu DF, Che LG, Su FC, , 1994. The malaria situation on the frontiers of Yunnan Province, China. Southeast Asian J Trop Med Public Health 25: 1924. [Google Scholar]
  30. Bureau of Endemic Diseases Control of People's Republic of China, 1998. Manual of Malaria Control. Beijing: People's Health Publishing Company. [Google Scholar]
  31. Ministry of Health of the People's Republic of China, 2006. Diagnostic Criteria for Malaria (WS 259-2006). Available at: http://www.moh.gov.cn/open/web_edit_file/20070604094905.pdf. Accessed October 16, 2012. [Google Scholar]
  32. Tabachnick BG, Fidell LS, , 2007. Using Multivariate Statistics. Boston: Pearson/Allyn & Bacon. [Google Scholar]
  33. Tian LW, Bi Y, Ho SC, Liu WJ, Liang S, Goggins WB, Chan EY, Zhou SS, Sung J, , 2008. One-year delayed effect of fog on malaria transmission: a time-series analysis in the rain forest area of Mengla County, south-west China. Malar J 7: 110.[Crossref] [Google Scholar]
  34. Hu H, Singhasivanon P, Salazar NP, Thimasarn K, Li XZ, Wu YX, Yang H, Zhu DF, Supavej S, Looarecsuwan S, , 1998. Factors influencing malaria endemicity in Yunnan Province, PR China (analysis of spatial pattern by GIS). Geographical Information System. Southeast Asian J Trop Med Public Health 29: 191200. [Google Scholar]
  35. Zhou SS, Wang Y, Tang LH, , 2006. Malaria Situation in the People's Republic of China in 2005. Chin J Parasitol Parasit Dis 24: 401403. [Google Scholar]
  36. Zhou SS, Wang Y, Xia Z, , 2011. Malaria situation in the People's Republic of China in 2009. Chin J Parasitol Parasit Dis 29: 13. [Google Scholar]
  37. Zhou SS, Wang Y, Li Y, , 2011. Malaria situation in the People's Republic of China in 2010. Chin J Parasitol Parasit Dis 29: 401403. [Google Scholar]
  38. Yang HL, Yang YM, Yang PF, Li XL, Gao BH, Zhang ZY, Yang ZQ, Cui LW, , 2008. Monitoring Plasmodium falciparum chloroquine resistance in Yunnan Province, China, 1981–2006. Acta Trop 108: 4449.[Crossref] [Google Scholar]
  39. Trape JF, Pison G, Preziosi MP, Enel C, Lou AD, Delaunay V, Samb B, Lagarde E, Molez JF, Simondon F, , 1998. Impact of chloroquine resistance on malaria mortality. C R Acad Sci III 321: 689697.[Crossref] [Google Scholar]
  40. Trape JF, , 2001. The public health impact of chloroquine resistance in Africa. Am J Trop Med Hyg 64: 1217. [Google Scholar]
  41. Sarah M, Xia M, Caroline J, Zhang ZX, Mary MC, , 2008. Border malaria in China: knowledge and use of personal protection by minority populations and implications for malaria control: a questionnaire-based survey. BMC Public Health 8: 344.[Crossref] [Google Scholar]
  42. Committee of Malaria Control and Prevention of China, 1991. Malaria Control and Prevention of China. Beijing: People's Health Publishing Company. [Google Scholar]
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  • Received : 03 Apr 2012
  • Accepted : 12 Nov 2012

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