1921
Volume 87, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The duration of anti-yellow fever (YF) virus immunoglobulin M (IgM) antibodies following YF vaccination is unknown, making it difficult to interpret positive IgM antibody results in previously vaccinated travelers. We evaluated the frequency and predictors of YF IgM antibody positivity 3–4 years following YF vaccination. Twenty-nine (73%) of 40 participants had YF IgM antibodies 3–4 years postvaccination. No demographic or exposure variables were predictive of YF IgM positivity. However, persons who were YF IgM positive at 3–4 years postvaccination had earlier onset viremia and higher neutralizing antibody geometric mean titers at 1 month and 3–4 years postvaccination compared with persons who were YF IgM negative. Detection of YF IgM antibodies several years postvaccination might reflect remote YF vaccination rather than recent YF vaccination or YF virus infection.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.2012.12-0182
2012-12-05
2018-12-15
Loading full text...

Full text loading...

/deliver/fulltext/14761645/87/6/1112.html?itemId=/content/journals/10.4269/ajtmh.2012.12-0182&mimeType=html&fmt=ahah

References

  1. Centers for Disease Control and Prevention, 2010. Yellow fever vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 59: 127. [Google Scholar]
  2. Jentes ES, Poumerol G, Gershman MD, Hill DR, Lemarchand J, Lewis RF, Staples JE, Tomori O, Wilder-Smith A, Monath TP, , 2011. The revised global yellow fever risk map and recommendations for vaccination, 2010: consensus of the informal WHO working group on geographic risk of yellow fever. Lancet Infect Dis 11: 622632.[Crossref] [Google Scholar]
  3. Monath TP, Teuwen D, Cetron M, Plotkin S, Orenstein W, Offit P, , 2008. Yellow fever vaccine. , eds. Vaccines. Fifth edition. China: Elsevier, 9591055. [Google Scholar]
  4. Monath TP, , 1971. Neutralizing antibody responses in the major immunoglobulin classes to yellow fever 17D vaccination of humans. Am J Epidemiol 93: 122129.[Crossref] [Google Scholar]
  5. Groot H, Riberiro RB, , 1962. Neutralizing and hemagglutination-inhibiting antibodies to yellow fever 17 years after vaccination with 17D vaccine. Bull World Health Organ 27: 699707. [Google Scholar]
  6. Poland JD, Calisher CH, Monath TP, Downs WG, Murphy K, , 1981. Persistence of neutralizing antibody 30–35 years after immunization with 17D yellow fever vaccine. Bull World Health Organ 59: 895900. [Google Scholar]
  7. Martin DA, Muth DA, Brown T, Johnson AJ, Karabatsos N, Roehrig JT, , 2000. Standardization of immunoglobulin M capture enzyme-linked immunosorbent assays for routine diagnosis of arboviral infections. J Clin Microbiol 38: 18231826. [Google Scholar]
  8. Beaty BJ, Calisher CH, Shope RE, Lennette EH, Lennette DA, Lennette ET, , 1995. Arboviruses. , eds. Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections. Seventh edition. Washington, DC: American Public Health Association, 189212. [Google Scholar]
  9. Miller JD, van der Most RG, Akondy RS, Glidewell JT, Albott S, Masopust D, Murali-Krishna K, Mahar PL, Edupuganti S, Lalor S, Germon S, Del Rio C, Mulligan MJ, Staprans SI, Altman JD, Feinberg MB, Ahmed R, , 2008. Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity 28: 710722.[Crossref] [Google Scholar]
  10. Darsie R, Ward R, , 2005. Identification and Geographical Distribution of the Mosquitoes of North America, North of Mexico. Gainesville, FL: University Press of Florida. [Google Scholar]
  11. de Melo AB, da Silva M da P, Magalhães MC, Gonzales Gil LH, Freese de Carvalho EM, Braga-Neto UM, Bertani GR, Marques ET, Jr Cordeiro MT, , 2011. Description of a prospective 17DD yellow fever vaccine cohort in Recife, Brazil. Am J Trop Med Hyg 85: 739747.[Crossref] [Google Scholar]
  12. Nogueira R, Schatzmayr H, Miagostovich M, Cavalcanti S, de Carvalho R, , 1992. Use of MAC-ELISA for evaluation of yellow fever vaccination. Rev Inst Med Trop Sao Paulo 34: 447450.[Crossref] [Google Scholar]
  13. Innis BL, Nisalak A, Nimmannitya S, Kusalerdchariya S, Chongswasdi V, Suntayakorn S, Puttisri P, Hoke CH, , 1989. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am J Trop Med Hyg 40: 418427. [Google Scholar]
  14. Lhuillier M, Sarthou J-L, , 1983. Anti-yellow fever IgM in the diagnosis and epidemiological surveillance of yellow fever. Ann Virol 134E: 349359. [Google Scholar]
  15. Kuno G, , 2001. Persistence of arboviruses and antiviral antibodies in vertebrate hosts: its occurrence and impacts. Rev Med Virol 11: 165190.[Crossref] [Google Scholar]
  16. Martínez MJ, Vilella A, Pumarola T, Roldan M, Sequera VG, Vera I, Hayes EB, , 2011. Persistence of yellow fever vaccine RNA in urine. Vaccine 29: 33743376.[Crossref] [Google Scholar]
  17. Penna HA, Bittencourt A, , 1943. Persistence of yellow fever virus in brains of monkeys immunized by cerebral inoculation. Science 97: 448449.[Crossref] [Google Scholar]
  18. Gould EA, Buckley A, Cane PA, Higgs S, Cammack N, , 1989. Use of a monoclonal antibody specific for wild-type yellow fever virus to identify a wild-type antigenic variant in 17D vaccine pools. J Gen Virol 70: 18891894.[Crossref] [Google Scholar]
  19. Kasturi SP, Skountzou I, Albrecht RA, Koutsonanos D, Hua T, Nakaya HI, Ravindran R, Stewart S, Alam M, Kwissa M, Villinger F, Murthy N, Steel J, Jacob J, Hogan RJ, García-Sastre A, Compans R, Pulendran B, , 2011. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 470: 543547.[Crossref] [Google Scholar]
  20. Meurman OH, , 1978. Persistence of immunoglobulin G and immunoglobulin M antibodies after postnatal rubella infection determined by solid-phase radioimmunoassay. J Clin Microbiol 7: 3438. [Google Scholar]
  21. Edelman R, Schneider RJ, Vejjajiva A, Pornpibul R, Voodhikul P, , 1976. Persistence of virus-specific IgM and clinical recovery after Japanese encephalitis. Am J Trop Med Hyg 25: 733738. [Google Scholar]
  22. Malvy D, Ezzedine K, Mamani-Matsuda M, Autran B, Toluo H, Receveur MC, Pistone T, Rambert J, Moynet D, Mossalayi D, , 2009. Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies. BMC Infect Dis 9: 200206.[Crossref] [Google Scholar]
  23. McAdam AJ, Farkash EA, Gewurz BE, Sharpe AH, , 2000. B7 co-stimulation is critical for antibody class switching and CD8+ cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J Virol 74: 203208.[Crossref] [Google Scholar]
  24. Fuse S, Obar JJ, Bellfy S, Leung E, Zhang W, Usherwood EJ, , 2006. CD80 and CD86 control antiviral CD8+ T-cell function and immune surveillance of murine gammaherpesvirus 68. J Virol 80: 91599170.[Crossref] [Google Scholar]
  25. Makino Y, Tadano M, Saito M, Maneekarn N, Sittisombut N, Sirisanthana V, Poneprasert B, Fukunaga T, , 1994. Studies on serological cross-reaction in sequential flavivirus infections. Microbiol Immunol 38: 951955.[Crossref] [Google Scholar]
  26. Reinhardt B, Jaspert R, Niedrig M, Kostner C, L'age-Stehr J, , 1998. Development of viremia and humoral and cellular parameters of immune activation after vaccination with yellow fever virus strain 17D: a model of human flavivirus infection. J Med Virol 56: 159167.[Crossref] [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2012.12-0182
Loading
/content/journals/10.4269/ajtmh.2012.12-0182
Loading

Data & Media loading...

  • Received : 21 Mar 2012
  • Accepted : 27 Aug 2012

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error