1921
Volume 87, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In Vietnam, and are responsible for most malaria infections, and and infections are rarely reported. Nevertheless, species-specific polymerase chain reaction analysis on 2,303 blood samples collected during a cross-sectional survey conducted in a forest area of central Vietnam identified 223 (9.7%) , 170 (7.4%) , 95 (4.1%) , and 19 (0.8%) mono-infections and 164 (7.1%) mixed infections. Of the 671 -positive samples by polymerase chain reaction, only 331 were detected by microscopy. Microscopy poorly diagnosed , , and mixed infections. Clinical and sub-clinical infections occurred in all age groups. The risk for infection and disease decreased with age, probably because of acquired partial immunity. The common occurrence of sub-patent infections seems to indicate that the malaria burden is underestimated and that diagnostic and therapeutic policies should be adapted accordingly.

[open-access] This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Received : 20 Jan 2012
  • Accepted : 11 Jun 2012
  • Published online : 05 Dec 2012
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