1921
Volume 87, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The role of in irritable bowel syndrome (IBS) is incompletely known. We aimed to investigate whether eradication of alleviates symptoms in IBS. Twenty-five positive IBS patients were treated with Metronidazole (MZ) or Tetracycline. The patients were mostly female (89%), and mean age (SD) was 35.1 (8.2) years. Microbiological response, evaluated 2 weeks post-treatment, was observed in 15 of 25 patients (60%), all by MZ. Clinical response, defined as adequate relief of symptoms, was observed in 7 of 22 patients (32%), all by MZ. In a logistic regression analysis, we found no significant association between clinical and microbiological response. This case study did not support our hypothesis of a simple association between and IBS. Some -infections were insufficiently treated by MZ. Further studies into the prevalence and effect of eradication of in IBS and into efficient treatments of are warranted.

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  • Received : 06 Dec 2011
  • Accepted : 09 Sep 2012
  • Published online : 05 Dec 2012

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