1921
Volume 86, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Amebiasis is a major cause of morbidity and mortality in the developing world. A reliable point-of-care test would help to improve diagnosis and early treatment. We evaluated a novel rapid fecal antigen detection test for (; TechLab, Inc., Blacksburg, VA), in a cohort of children in Bangladesh where amebiasis is endemic. This point-of-care test had a sensitivity of 100% and a specificity of 100% when compared with enzyme-linked immunosorbent assay antigen detection.

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2012-06-01
2017-09-22
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References

  1. World Health Organization, 1997. Amoebiasis. Wkly Epidemiol Rec 72: 97100.
  2. Haque R, Huston CD, Hughes M, Houpt E, Petri WA, , 2003. Current concepts: amebiasis. N Engl J Med 348: 15651573.[Crossref]
  3. Pillai DR, Keystone JS, Sheppard DC, MacLean JD, MacPherson DW, Kain KC, , 1999. E. histolytica and E. dispar: epidemiology and comparison of diagnostic methods in setting of nonendemicity. Clin Infect Dis 29: 13151318.[Crossref]
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  6. Haque R, Mollah NU, Ali KM, Eubanks A, Lyerly D, Petri WA, , 2000. Diagnosis of amebic liver abscess and intestinal infection with the TechLab Entamoeba histolytica II antigen detection and anti-body tests. J Clin Microbiol 38: 32353239.
  7. Petri WA, Snodgrass TL, Jackson TF, Gathiram V, Simjee AE, Chadee K, Kain KC, , 1990. Monoclonal antibodies directed against the galactose-binding lectin of Entamoeba histolytica enhance adherence. J Immunol 144: 48034809.
  8. Leo M, Haque R, Kabir M, Roy S, Lahlou RM, Mondal D, Tannich E, Petri WA, , 2006. Evaluation of Entamoeba histolytica antigen and antibody point-of-care tests for the rapid diagnosis of amebiasis. J Clin Microbiol 44: 45694571.[Crossref]
  9. Walsh J, , 1986. Problems in recognition and diagnosis of amebiasis: estimation of the global magnitude of morbidity and mortality. Clin Infect Dis 8: 228238.[Crossref]
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  • Received : 24 Oct 2011
  • Accepted : 04 Mar 2012

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