1921
Volume 86, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

An 18-year-old man developed posterior reversible leukoencephalopaty after being bitten by a venomous snake (). It is possible that this previously unrecognized neurological complication of snake bite envenoming occurred as the result of endothelial dysfunction induced by the venom of the offending snake. This pathogenetic mechanism has also been implicated as the cause of cerebral infarctions in snake bite victims. Alternatively, the leukoencephalopathy might have been a complication of antivenom therapy.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2012.11-0610
2012-03-01
2017-11-20
Loading full text...

Full text loading...

/deliver/fulltext/14761645/86/3/496.html?itemId=/content/journals/10.4269/ajtmh.2012.11-0610&mimeType=html&fmt=ahah

References

  1. Kasturiratne A, Wickremasinghe AR, de Silva N, Gunawardena NK, Pathmeswaran A, Premaratna R, Savioli L, Lalloo DG, de Silva HJ, , 2008. The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med 5: e218.[Crossref]
  2. Mohapatra B, Warrell DA, Suraweera W, Bhatia P, Dhingra N, Jotkar RM, Rodriguez PS, Mishra K, Whitaker R, Jha P, Million Death Study Collaborators, 2011. Snakebite mortality in India: a nationally representative mortality survey. PLoS Negl Trop Dis 5: e1018.[Crossref]
  3. Warrell DA, , 2010. Snake bite. Lancet 375: 7788.
  4. Doley R, Kini RM, , 2009. Protein complexes in snake venom. Cell Mol Life Sci 66: 28512871.[Crossref]
  5. Del Brutto OH, Del Brutto VJ, , 2011. Neurological complications of snake bites: a review. Neurol Scand, DOI:10.1111/j.1600-0404.2011.01593.x.
  6. Lewis RL, Gutmann L, , 2004. Snake venoms and the neuromuscular junction. Semin Neurol 24: 175179.[Crossref]
  7. Mosquera A, Idrovo LA, Tafur A, Del Brutto OH, , 2003. Stroke following Bothrops spp. snakebite. Neurology 60: 15771580.[Crossref]
  8. Malbranque S, Piercecchi-Marti MD, Thomas L, Barbey C, Courcier D, Bucher B, Ridarch A, Smadja A, Warrell DA, 2008. Fatal diffuse thrombotic microengiopathy after a bite by the “Fer-de-Lance” pit viper (Bothrops lanceolatus) of Martinique. Am J Trop Med Hyg 78: 856861.
  9. Hung D-Z, Wu M-L, Deng J-F, Yang D-Y, Lin-Shiau S-Y, , 2002. Multiple thrombotic occlusions of vessels after Russell's viper envenoming. Pharmacol Toxicol 91: 106110.[Crossref]
  10. Cisneros-Heredia DF, Touzet J-M, , 2004. Distribution and conservation status of Bothrops asper (Garman, 1984) in Ecuador. Herpetozoa (Wien) 17: 135141.
  11. Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR, , 1996. A reversible posterior leukoencephalopathy syndrome. N Engl J Med 334: 494500.[Crossref]
  12. Tormoehlen LM, , 2011. Toxic leukoencephalopathies. Neurol Clin 29: 591605.[Crossref]
  13. Tam CS, Galanos J, Seymour JF, Pitman AG, Stark RJ, Prince HM, , 2004. Reversible posterior leukoencephalopathy syndrome complicating cytotoxic chemotherapy for hematologic malignancies. Am J Hematol 77: 7276.[Crossref]
  14. Bartynski WS, , 2008. Posterior reversible encephalopathy syndrome, part I: fundamental imaging and clinical features. AJNR Am J Neuroradiol 29: 10361042.[Crossref]
  15. Bartynski WS, , 2008. Posterior reversible encephalopathy syndrome, part II: controversies surrounding pathophysiology of vasogenic edema. AJNR Am J Neuroradiol 29: 10431049.[Crossref]
  16. Gutiérrez JM, Escalante T, Rucavado A, , 2009. Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom. Toxicon 54: 976987.[Crossref]
  17. Mathur SP, , 1959. Allergy to antivenin serum. Br J Ophthalmol 43: 5051.[Crossref]
  18. Malhotra P, Sharma N, Awasthi A, Vasishta RK, , 2005. Fatal acute disseminated encephalomyelitis following treated snake bite in India. Emerg Med J 22: 308309.[Crossref]
  19. Tripathy S, Routray PK, Mohapatra AK, Mohapatra M, Dash SC, , 2010. Acute demyelinating encephalomyelitis after antivenom therapy in Russell's viper bite. J Med Toxicol 6: 318321.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2012.11-0610
Loading
/content/journals/10.4269/ajtmh.2012.11-0610
Loading

Data & Media loading...

  • Received : 03 Oct 2011
  • Accepted : 14 Dec 2011

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error