1921
Volume 86, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Molecular characterization of has led to better understanding of microsporidiosis transmission in humans. This study aimed to detect and genotype in human immunodeficiency virus (HIV)-infected persons. Stool specimens were collected from 463 HIV-infected patients and analyzed for by polymerase chain reaction (PCR) and DNA sequence analysis of the internal transcribed spacer. was detected in 77 HIV patients. CD4 cell counts < 200 cells/μL was associated with infection ( = 0.09). was significantly associated with weight loss ( < 0.0001), diarrhea ( = 0.006), fever ( < 0.0001), not being married ( < 0.0001), and flush type of toilet ( = 0.0007). Six known genotypes of D, A, IV, CAF2, EbpA, and Peru 8 in 31, 22, 14, 2, 1, and 1 patients, respectively, five novel genotypes of , and one infection with mixed genotypes were observed in this study. Three of the novel genotypes were genetically distant to the genotypes commonly found in humans.

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  • Received : 28 Aug 2011
  • Accepted : 26 Nov 2011

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