Volume 87, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



mosquitoes are important vectors of re-emerging diseases in developing countries, and increasing exposure to in the developed world is currently a source of concern. Given the limitations of current entomologic methods, there is a need for a new effective way for evaluating exposure. Our objective was to evaluate specific antibody responses to saliva as a biomarker for vector exposure in a dengue-endemic urban area. IgG responses to saliva were strong in young children and steadily waned with age. Specific IgG levels were significantly higher in persons living in sites with higher density, as measured by using entomologic parameters. Logistic regression showed a significant correlation between IgG to saliva and exposure level, independently of either age or sex. These results suggest that antibody responses to saliva could be used to monitor human exposure to bites.


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  • Received : 22 Jul 2011
  • Accepted : 15 Apr 2012

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