Volume 86, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Of eight children given a diagnosis of dengue, a complicated course developed in three (38%), including one infant with dengue shock syndrome. Children visiting friends and relatives in dengue-endemic regions are at risk for severe dengue-associated morbidity. Children of families originally from these locations may benefit from pre-travel advice and may represent candidates for a future dengue vaccine.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Wilder-Smith A, Schwartz E, , 2005. Dengue in travelers. N Engl J Med 353: 924932.[Crossref] [Google Scholar]
  2. Hammond SN, Balmaseda A, Pérez L, Tellez Y, Saborio SI, Mercado JC, Videa E, Rodriguez Y, Pérez MA, Cuadra R, Solano S, Rocha J, Idiaquez W, Gonzalez A, Harris E, , 2005. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg 73: 10631070. [Google Scholar]
  3. Wichmann O, Gascon J, Schunk M, Puente S, Siikamaki H, Gjørup I, Lopez-Velez R, Clerinx J, Peyerl-Hoffmann G, Sundøy A, Genton B, Kern P, Calleri G, de Górgolas M, Mühlberger N, Jelinek T, , 2007. Severe dengue virus infection in travelers: risk factors and laboratory indicators. J Infect Dis 195: 10891096.[Crossref] [Google Scholar]
  4. Hagmann S, Neugebauer R, Schwartz E, Neugebauer R, Schwartz E, Perret C, Castelli F, Barnett ED, Stauffer WM, , 2010. Illness in children after international travel: analysis from the GeoSentinel Surveillance Network. Pediatrics 125: e1072e1080.[Crossref] [Google Scholar]
  5. Groen J, Koraka P, Velzing J, Copra C, Osterhaus AD, , 2000. Evaluation of six immunoassays for detection of dengue virus-specific immunoglobulin M and G antibodies. Clin Diagn Lab Immunol 7: 867871. [Google Scholar]
  6. U.S. Census Bureau. Available at: http://quickfacts.census.gov/qfd/states/36/36005.html. Accessed June 15, 2011.
  7. San Martín JL, Brathwaite O, Zambrano B, Solórzano JO, Bouckenooghe A, Dayan GH, Guzmán MG, , 2010. The epidemiology of dengue in the Americas over the last three decades: a worrisome reality. Am J Trop Med Hyg 82: 128135.[Crossref] [Google Scholar]
  8. Mohammed HP, Ramos MM, Rivera A, Johansson M, Muñoz-Jordan JL, Sun W, Tomashek K, , 2010. Travel-associated dengue infections in the United States, 1996 to 2005. J Travel Med 17: 814.[Crossref] [Google Scholar]
  9. Leder K, Tong S, Weld L, Kain KC, Wilder-Smith A, von Sonnenburg F, Black J, Brown GV, Torresi J, , 2006. Illness in travelers visitng friends and relatives: a review of the GeoSentinel network. Clin Infect Dis 43: 11851193.[Crossref] [Google Scholar]
  10. Choi S-H, Kim Y-J, Shin JH, Yoo KH, Sung KW, Koo HH, , 2010. International travel of Korean children and dengue fever: a single institutional analysis. Korean J Pediatr 53: 701704.[Crossref] [Google Scholar]
  11. TDR. World Health Organization Issues New Dengue Guidelines. Available at http://apps.who.int/tdr/svc/publications/tdrnews/issue-85/tdr-briefly. Accessed June 20, 2011. [Google Scholar]
  12. Libraty DH, Acosta LP, Tallo V, Segubre-Mercado E, Bautista A, Potts JA, Jarman RG, Yoon IK, Gibbons RV, Brion JD, Capeding RZ, , 2009. A prospective nested case-control study of dengue in infants: rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model. PLoS Med 6: e1000171. [Google Scholar]
  13. Wilder-Smith A, Ooi EE, Vasudevan SG, Gubler DJ, , 2010. Update on dengue: epidemiology, virus evolution, antiviral drugs, and vaccine development. Curr Infect Dis Rep 12: 157164.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 26 Jun 2011
  • Accepted : 23 Nov 2011
  • Published online : 01 Mar 2012

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error