1921
Volume 87, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Tungiasis is a zoonosis caused by . In Brazil, tungiasis is endemic in many resource-poor communities, in which various domestic and sylvatic animals act as reservoirs. Eighty laboratory-raised Wistar rats were exposed to in areas of intense transmission: a fishing village and an urban shantytown in Ceará State, northeast Brazil. The topographic distribution of lesions in Wistar rats was compared with the distribution of lesions in humans in the same area. Our results show that the topographic distribution of embedded sand fleas was almost identical in Wistar rats and humans and that lesions were confined to the feet. In humans, 76% of all lesions were located periungually, whereas in Wistar rats, 67% of lesions were located at the distal end of the digits ( = 0.73). Both had the majority of lesions at the toes and digits: 70.2% versus 65.7% ( = 0.79). The Wistar rat model mirrors human tungiasis in topographic distribution.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2012.11-0073
2012-07-02
2017-09-25
Loading full text...

Full text loading...

/deliver/fulltext/14761645/87/1/125.html?itemId=/content/journals/10.4269/ajtmh.2012.11-0073&mimeType=html&fmt=ahah

References

  1. Linardi P, , 2000. Sifonápteros do Brasil. São Paulo, Brazil: Museu de Zoologia da Universidade de São Paulo, 48.
  2. Falkenstein J, , 1877. Über das Verhalten der Haut in den Tropen, ihre Pflege und Krankheiten. Virchows Arch Pathol Anat Physiol Klin Med 71: 421440.[Crossref]
  3. Hesse P, , 1899. Die ausbreitung des sandflohs in Afrika. Geogr Z 1: 522530.
  4. Wolffhügel K, , 1910. Die flöhe (siphonaptera) der haustiere. Z Infektionskr Haustiere 8: 354382.
  5. Rietschel W, , 1989. Observations of the sand flea (Tunga penetrans) in humans and dogs in French Guiana. Tierarztl Prax 17: 189193.
  6. Franco da Silva LA, Teixeira Borges G, Santana AP, , 2001. Alguns aspectos epidemiológicos e profiláticos da tungíase em cães de Jataí, GO. Rev Patol Trop 30: 6973.
  7. Heukelbach J, da Costa AL, Wilcke T, Mencke N, Feldmeier H, , 2004. The animal reservoir of Tunga penetrans in severely affected communities of north-east Brazil. Med Vet Entomol 18: 329335.[Crossref]
  8. Cooper JE, , 1967. An outbreak of Tunga penetrans in a pig herd. Vet Rec 80: 365366.[Crossref]
  9. Vaz Z, Rocha UF, , 1946. Tunga penetrans (L.,1758), “bicho de pé” em gado bovino. Livro de homenagem a R.F. Almeida 40: 327332.
  10. Trentini M, Pampiglione S, Giannetto S, Finocchiario B, , 2000. Observations about specimens of Tunga sp. (Siphonaptera, Tungidae) extracted from goats of Ecuador. Parasitologia 42: 65.
  11. Karsten H, , 1865. Beitrag zur kenntnis des Rhynchoprion penetrans . Virchows Arch Pathol Anat Physiol Klin Med 32: 269292.[Crossref]
  12. Fülleborn F, , 1908. Untersuchungen über den sandfloh. Arch Schiffs u Tropenkr 6: 269273.
  13. Feldmeier H, Eisele M, Sabóia-Moura RC, Heukelbach J, , 2003. Severe tungiasis in underprivileged communities: case series from Brazil. Emerg Infect Dis 9: 949955.[Crossref]
  14. Witt L, Heukelbach J, Schwalfenberg S, Ribeiro RA, Harms G, Feldmeier H, , 2007. Infestation of Wistar rats with Tunga penetrans in different microenvironments. Am J Trop Med Hyg 76: 666668.
  15. Buckendahl J, Kehr JD, Seidenschwang M, Heukelbach J, Feldmeier H, , 2010. Control of tungiasis through morbidity reduction: a randomized controlled intervention study in a resource-poor community in Brazil. PLoS Negl Trop Dis 4: e879.[Crossref]
  16. Heukelbach J, Wilcke T, Eisele M, Feldmeier H, , 2002. Ectopic localization of tungiasis. Am J Trop Med Hyg 67: 214216.
  17. Muehlen M, Heukelbach J, Wilcke T, Winter B, Mehlhorn H, Feldmeier H, , 2003. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. II. Prevalence, parasite load and topographic distribution of lesions in the population of a traditional fishing village. Parasitol Res 90: 449455.[Crossref]
  18. Pampiglione S, Fioravanti ML, Gustinelli A, Onore G, Mantovani B, Luchetti A, Trentini M, , 2009. Sand flea (Tunga spp.) infections in humans and domestic animals: state of the art. Med Vet Entomol 23: 172186.[Crossref]
  19. Feldmeier H, Witt L, Schwalfenberg S, Linardi PM, Ribeiro RA, Capaz RA, Van Marck E, Meckes O, Mehlhorn H, Mencke N, Heukelbach J, , 2007. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. VI. Natural history of the infestation in laboratory-raised Wistar rats. Parasitol Res 102: 113.[Crossref]
  20. Ariza L, Seidenschwang M, Buckendahl J, Gomide M, Feldmeier H, Heukelbach J, , 2007. Tungiasis: a neglected disease causing severe morbidity in a shantytown in Fortaleza, State of Ceará. Rev Soc Bras Med Trop 40: 6367.[Crossref]
  21. Feldmeier H, Witt LH, Schwalfenberg S, Albuquerque Ribeiro R, Queiroz Cunha F, Harms G, Mehlhorn H, Liesenfeld O, Heukelbach J, , 2004. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. V. Cytokine concentrations in experimentally infected Wistar rats. Parasitol Res 94: 371376.[Crossref]
  22. Eisele M, Heukelbach J, Van Marck E, Mehlhorn H, Meckes O, Franck S, Feldmeier H, , 2003. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. I. Natural history of tungiasis in man. Parasitol Res 90: 8792.
  23. Pilger D, Schwalfenberg S, Heukelbach J, Witt L, Mencke N, Khakban A, Feldmeier H, , 2008. Controlling tungiasis in an impoverished community: an intervention study. PLoS Negl Trop Dis 2: e324.[Crossref]
  24. Ugbomoiko US, Ofoezie IE, Heukelbach J, , 2007. Tungiasis: high prevalence, parasite load, and morbidity in a rural community in Lagos State, Nigeria. Int J Dermatol 46: 475481.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2012.11-0073
Loading
/content/journals/10.4269/ajtmh.2012.11-0073
Loading

Data & Media loading...

  • Received : 03 Feb 2011
  • Accepted : 03 Feb 2012

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error