1921
Volume 85, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Outbreaks of Mayaro fever have been associated with a sylvatic cycle of Mayaro virus (MAYV) transmission in South America. To evaluate the potential for a common urban mosquito to transmit MAYV, laboratory vector competence studies were performed with from Iquitos, Peru. Oral infection in ranged from 0% (0/31) to 84% (31/37), with blood meal virus titers between 3.4 log and 7.3 log plaque-forming units (PFU)/mL. Transmission of MAYV by 70% (21/30) of infected mosquitoes was shown by saliva collection and exposure to suckling mice. Amount of viral RNA in febrile humans, determined by real-time polymerase chain reaction, ranged from 2.7 to 5.3 log PFU equivalents/mL. Oral susceptibility of to MAYV at titers encountered in viremic humans may limit opportunities to initiate an urban cycle; however, transmission of MAYV by shows the vector competence of this species and suggests potential for urban transmission.

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  • Received : 07 Jun 2011
  • Accepted : 16 Jul 2011

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