Volume 85, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A field trial was conducted in a Lyme disease-endemic area of New Jersey to determine the efficacy of a doxycyline hyclate rodent bait to prophylactically protect and cure small-mammal reservoirs and reduce infection rates in questing ticks for and . The doxycycline-laden bait was formulated at a concentration of 500 mg/kg and delivered during the immature tick feeding season in rodent-targeted bait boxes. The percentage of infected small mammals recovered from treated areas after 2 years of treatment was reduced by 86.9% for and 74% for . Infection rates in questing nymphal ticks for both and were reduced by 94.3% and 92%, respectively. Results from this study indicate that doxycycline-impregnated bait is an effective means of reducing infection rates for and in both rodent reservoirs and questing ticks.


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  • Received : 06 May 2011
  • Accepted : 30 Aug 2011
  • Published online : 01 Dec 2011

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