Volume 85, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We herein report a case of a young Japanese female who was confirmed to have cystic echinococcosis (CE) 1 stage based on the World Health Organization Informal Working Group on Echinococcosis pathological classification of CE, and she was also suspected to be infected with eggs of the G1 sensu stricto during her stay in the United Kingdom and therefore, suffered from synchronous pulmonary and hepatic CE. Oral albendazole was administered initially, but rupture of a lung hydatid cyst was observed. To avoid additional rupture, we performed two surgeries. CE is very rare in Japan; all CE cases in Japan during the past two decades have been confirmed to be imported, and almost all cases are hepatic CE. This case is the first case report of a Japanese patient who had concomitant giant lung and liver CE with early-stage CE1 and was successfully treated by surgery and pharmacotherapy with a serological follow-up.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Eckert J, Conraths FJ, Tackmann K, , 2000. Echinococcosis: an emerging or re-emerging zoonosis? Int J Parasitol 30: 12831294.[Crossref] [Google Scholar]
  2. Eckert J, Gemmell MA, Meslin FX, Pawlowski ZS, , 2001. WHO/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern. Geneva, Switzerland: World Health Organization. [Google Scholar]
  3. Brunetti E, Kern P, Vuitton DA, , Writing Panel for the WHO-IWGE, 2010. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 114: 116.[Crossref] [Google Scholar]
  4. Hatakeyama Y, Sato N, Koyama Y, Inoue N, Takenosita S, Takeuchi S, Ito A, , 2002. One surgical case of hepatic cystic echinococcosis. Shujutsu 56: 819823. [Google Scholar]
  5. Doi R, Ito A, Watanabe H, Morishima H, , 2003. Cystic hydatidosis—its occurrence and prevention in Japan. Nippon Koshu Eisei Zasshi 50: 10661078. [Google Scholar]
  6. Kimura M, Nakamura T, Iwamoto A, Nishimura Y, Egawa T, Ito A, , 1999. Cystic echinococcosis in a Jordanian patient: albendazole in a short-term immigrant. J Travel Med 6: 249253.[Crossref] [Google Scholar]
  7. Ito A, Okamoto M, Ishiguro T, Ma L, Suzuki H, Yasui A, Shigeta H, Matsuura T, Hosokawa T, Chai JJ, , 1998. Short report: an imported case of cystic echinococcosis in Japan diagnosed by imaging and serology with confirmation of Echinococcus granulosus-specific DNA sequences. Am J Trop Med Hyg 58: 790792. [Google Scholar]
  8. Mamuti W, Yamasaki H, Sako Y, Nakao M, Xiao N, Nakaya K, Sato N, Vuitton DA, Piarroux R, Lightowlers MW, Craig PS, Ito A, , 2004. Molecular cloning, expression, and serological evaluation of an 8-kilodalton subunit of antigen B from Echinococcus multilocularis . J Clin Microbiol 42: 10821088.[Crossref] [Google Scholar]
  9. Li T, Ito A, Chen X, Sako Y, Qiu J, Xiao N, Qiu D, Nakao M, Yanagida T, Craig PS, , 2010. Specific IgG responses to recombinant antigen B and em18 in cystic and alveolar echinococcosis in china. Clin Vaccine Immunol 17: 470475.[Crossref] [Google Scholar]
  10. Ito A, Nakao M, Sako Y, , 2007. Echinococcosis: serological detection of patients and molecular identification of parasites. Future Microbiol 2: 439449.[Crossref] [Google Scholar]
  11. Nakao M, McManus DP, Schantz PM, Craig PS, Ito A, , 2007. A molecular phylogeny of the genus Echinococcus inferred from complete mitochondrial genomes. Parasitology 134: 713722.[Crossref] [Google Scholar]
  12. Mawhorter S, Temeck B, Chang R, Pass H, Nash T, , 1997. Nonsurgical therapy for pulmonary hydatid cyst disease. Chest 112: 14321436.[Crossref] [Google Scholar]
  13. Kurkcuoglu IC, Eroglu A, Karaoglanoglu N, Polat P, , 2002. Complications of albendazole treatment in hydatid disease of lung. Eur J Cardiothorac Surg 22: 649650.[Crossref] [Google Scholar]
  14. Dhaliwal RS, Kallat MS, , 1997. One-stage surgical procedure for bilateral lung and liver cysts. Ann Thorac Surg 64: 338341.[Crossref] [Google Scholar]
  15. Santivanez S, Garcia HH, , 2010. Pulmonary cystic echinococcosis. Curr Opin Pulm Med 16: 257261. [Google Scholar]
  16. Kurkcuoglu IC, Eroglu A, Karaoglanoglu N, Polat P, , 2002. Complications of albendazole treatment in hydatid disease of lung. Eur J Cardiothorac Surg 22: 649650.[Crossref] [Google Scholar]
  17. Smego RA, Jr Bhatti S, Khaliq AA, Beg MA, , 2003. Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a meta-analysis. Clin Infect Dis 37: 10731083.[Crossref] [Google Scholar]
  18. Aktan AO, Yalin R, , 1996. Preoperative albendazole treatment for liver hydatid disease decreases the viability of the cyst. Eur J Gastroenterol Hepatol 8: 877879. [Google Scholar]
  19. Erzurumlu K, Hökelek M, Gönlüsen L, Tas K, Amanvermez R, , 2000. The effect of albendazole on the prevention of secondary hydatidosis. Hepatogastroenterology 47: 247250. [Google Scholar]
  20. Celik M, Senol C, Keles M, Halezeroglu S, Urek S, Haciibrahimoglu G, Ersev AA, Arman B, , 2000. Surgical treatment of pulmonary hydatid disease in children: report of 122 cases. J Pediatr Surg 35: 17101713.[Crossref] [Google Scholar]
  21. Doğan R, Yüksel M, Cetin G, Süzer K, Alp M, Kaya S, Unlü M, Moldibi B, , 1989. Surgical treatment of hydatid cysts of the lung: report on 1055 patients. Thorax 44: 192199.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 23 Feb 2011
  • Accepted : 01 Jun 2011
  • Published online : 01 Sep 2011

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error