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Volume 85, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The main objective of this study was to measure the quality of life (QoL) during a dengue episode. We conducted a facility-based survey in central Brazil in 2005 and recruited 372 laboratory-confirmed dengue patients greater than 12 years of age in hospital and ambulatory settings. We administered the World Health Organization QoL instrument approximately 15 days after the onset of symptoms. We used principal component analysis with varimax rotation to identify domains related to QoL. The median age of interviewees was 36 years. Most (85%) reported their general health status as very good or good before the dengue episode. Although ambulatory patients were mainly classified as having dengue fever, 44.8% of hospitalized patients had dengue hemorrhagic fever or intermediate dengue. Principal component analysis identified five principal components related to cognition, sleep and energy, mobility, self-care, pain, and discomfort, which explained 73% of the variability of the data matrix. Hospitalized patients had significantly lower mean scores for dimensions cognition, self-care, and pain than ambulatory patients. This investigation documented the generally poor QoL during a dengue episode caused by the large number of domains affected and significant differences between health care settings.

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2011-10-01
2017-11-22
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References

  1. World Health Organization, 2008. Dengue and Dengue Haemorrhagic Fever. Fact Sheet No. 117. Available at: http://www.who.int/mediacentre/factsheets/fs117/en/. Accessed August 15, 2008.
  2. Halstead SB, , 2007. Dengue. Lancet 370: 16441652.[Crossref]
  3. Suaya JA, Shepard DS, Chang MS, Caram M, Hoyer S, Socheat D, Chantha N, Nathan MB, , 2007. Cost-effectiveness of annual targeted larviciding campaigns in Cambodia against the dengue vector Aedes aegypti . Trop Med Int Health 12: 10261036.[Crossref]
  4. Gubler DJ, , 2002. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol 10: 100103.[Crossref]
  5. Guzman MG, Kouri G, , 2003. Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. J Clin Virol 27: 113.[Crossref]
  6. San Martin JL, Brathwaite O, Zambrano B, Solórzano JO, Bouckenooghe A, Dayan GH, Guzmán MG, , 2010. The epidemiology of dengue in the Americas over the last three decades: a worrisome reality. Am J Trop Med Hyg 82: 128135.[Crossref]
  7. Teixeira MG, Costa Mda C, Barreto F, Barreto ML, , 2009. Dengue: twenty-five years since reemergence in Brazil. Cad Saude Publica 25 (Suppl 1): S7S18.
  8. Ministry of Health, 2007. Information System for Disease Reporting. Available at: http://dtr2004.sayde.gov.br/sinanweb/novo/. Accessed September 10, 2010.
  9. World Health Organization, 2007. Impact of Dengue. Available at: http://www.who.int/tdr/publications/tdrnews/news64/dengue.htm. Accessed August 15, 2008.
  10. Silva JB, Jr Siqueira Júnior JB, Coelho GE, Vilarinhos PT, Pimenta FG, Jr, 2002. Dengue in Brazil: current situation and prevention and control activities. Epidemiol Bull 23: 36.
  11. Siqueira JB, Jr Martelli CM, Coelho GE, Simplicio AC, Hatch DL, , 2005. Dengue and dengue hemorrhagic fever, Brazil, 1981–2002. Emerg Infect Dis 11: 4853.[Crossref]
  12. Suaya JA, Shepard DS, Beatty ME, , 2006. Dengue: burden of disease and costs of illness. Report of the Scientific Working Group on Dengue. Geneva: World Health Organization.
  13. Teixeira MG, Costa MC, Coelho G, Barreto ML, , 2008. Recent shift in age pattern of dengue hemorrhagic fever, Brazil. Emerg Infect Dis 14: 1663.[Crossref]
  14. Anderson KB, Chunsuttiwat S, Nisalak A, Mammen MP, Libraty DH, Rothman AL, Green S, Vaughn DW, Ennis FA, Endy TP, , 2007. Burden of symptomatic dengue infection in children at primary school in Thailand: a prospective study. Lancet 369: 14521459.[Crossref]
  15. Anez G, Balza R, Valero N, Larreal Y, , 2006. Economic impact of dengue and dengue hemorrhagic fever in the State of Zulia, Venezuela, 1997–2003. Rev Panam Salud Publica 19: 314320.[Crossref]
  16. Guzman MG, Triana C, Bravo J, Kouri G, , 1992. The estimation of the economic damages caused as a consequence of the epidemic of hemorrhagic dengue in Cuba in 1981. Rev Cubana Med Trop 44: 1317.
  17. Luz PM, Grinsztejn B, Galvani AP, , 2009. Disability adjusted life years lost to dengue in Brazil. Trop Med Int Health 14: 237246.[Crossref]
  18. Torres JR, Castro J, , 2007. The health and economic impact of dengue in Latin America. Cad Saude Publica 23 (Suppl 1): S23S31.
  19. Valdes L, Mizhrahi JV, Guzman MG, , 2002. Impacto económico de la epidemia de dengue 2 en Santiago de Cuba, 1997. Rev Cubana Med Trop 54: 220227.
  20. Armien B, Suaya JA, Quiroz E, Sak BK, Bayard V, Marchena L, Campos C, Shepard DS, , 2008. Clinical characteristics and national economic cost of the 2005 dengue epidemic in Panama. Am J Trop Med Hyg 79: 364371.
  21. Halstead SB, Deen J, , 2002. The future of dengue vaccines. Lancet 360: 12431245.[Crossref]
  22. Lum LC, Suaya JA, Tan LH, Sah BK, Shepard DS, , 2008. Quality of life of dengue patients. Am J Trop Med Hyg 78: 862867.
  23. Shepard DS, Suaya JA, Halstead SB, Nathan MB, Gubler DJ, Mahoney RT, Wang DN, Meltzer MI, , 2004. Cost-effectiveness of a pediatric dengue vaccine. Vaccine 22: 12751280.[Crossref]
  24. Suaya JA, Siqueira JB, Martelli CM, Lum L, Shepard DS, , 2009. Cost of dengue cases in eight countries in the Americas and Asia: a prospective study. Am J Trop Med Hyg 80: 846855.
  25. Centers for Disease Control, 2000. Health-related quality of life among adults with arthritis: behaviour and risk factors surveillance system in 11 states, 1996–1998. JAMA 283: 27832785.
  26. Gouveia VV, Barbosa GA, Oliveira Andrade E, Carneiro MB, , 2010. Factorial validity and reliability of the General Health Questionnaire (GHQ-12) in the Brazilian physician population. Cad Saude Publica 26: 14391445.[Crossref]
  27. Wu AW, , 1997. Application of medical outcomes study health-related quality of measures in HIV/AIDS. Qual Life Res 6: 531543.[Crossref]
  28. Fitzpatrick R, Fletcher A, Gore S, Jones D, Spiegelhalter D, Cox D, , 1992. Quality of life measures in health care. I: applications and issues in assessment. BMJ 305: 10741077.[Crossref]
  29. Horner-Johnson W, Krahn G, Andresen E, Hall T, , 2009. Developing summary scores of health-related quality of life for a population-based survey. Public Health Rep 124: 103110.
  30. Testa MA, Simonson DC, , 1996. Assessment of quality-of-life outcomes. N Engl J Med 334: 835840.[Crossref]
  31. Ministry of Health, 2005. Dengue: Diagnosis and Clinical Handling. Available at: http://portal.saude.gov.br/portal/arquivos/pdf/dengue_manejo_clinico_2006.pdf. Accessed September 18, 2010.
  32. World Health Organization, 2002. World Health Survey Instruments and Related Documents. Geneva. World Health Organization.
  33. Gouveia GC, Souza WV, Luna CF, Souza Jrn PR, Szwarcwald CL, , 2009. User satisfaction in the Brazilian health system: associated factors and regional differences. Rev Bras Epidemiol 12: 281296.[Crossref]
  34. Hsiung PC, Fang CT, Chang YY, Chen MY, Wang JD, , 2005. Comparison of WHOQOL-BREF and SF-36 in patients with HIV infection. Qual Life Res 14: 141150.[Crossref]
  35. The WHOQOL Group, 1998. The World Health Organization Quality Of Life Assessment (WHOQOL): development and general psychometric properties. Soc Sci Med 46: 15691585.[Crossref]
  36. EuroQol Group, 1990. A new facility for the measurement of health-related quality of life. Health Policy (New York) 16: 199208.
  37. Meyers LS, Gamst G, Guarino AJ, , 2006. Principal components and factor analysis. Applied Multivariate Research. Design and Interpretation. Thousand Oaks, CA: SAGE Publications, 465513.
  38. Cruz LN, Camey SA, Fleck MP, Polanczyk CA, , 2009. World Health Organization quality of life instrument-brief and Short Form-36 in patients with coronary artery disease: do they measure similar quality of life concepts? Psychol Health Med 14: 619628.[Crossref]
  39. Fleck MP, Louzada S, Xavier M, Chachamovich E, Vieira G, Santos L, Pinzon V, , 2000. Application of the Portuguese version of the abbreviated instrument of quality life [WHOQOL-BREF] [in Portuguese]. Rev Saude Publica 34: 178183.[Crossref]
  40. Gubler DJ, , 1998. Dengue and dengue hemorrhagic fever. Clin Microbiol Rev 11: 480496.
  41. Guilarde AO, Turchi MD, Siqueira JB, Jr Feres VC, Rocha B, Levi JE, Souza VA, Boas LS, Pannuti CS, Martelli CM, , 2008. Dengue and dengue hemorrhagic fever among adults: clinical outcomes related to viremia, serotypes, and antibody response. J Infect Dis 197: 817824.[Crossref]
  42. Harris E, Videa E, Pérez L, Sandoval E, Téllez Y, Pérez ML, Cuadra R, Rocha J, Idiaquez W, Alonso RE, Delgado MA, Campo LA, Acevedo F, Gonzalez A, Amador JJ, Balmaseda A, , 2000. Clinical, epidemiologic, and virologic features of dengue in the 1998 epidemic in Nicaragua. Am J Trop Med Hyg 63: 511.
  43. Brazier J, Roberts J, Deverill M, , 2002. The estimation of a preference-based measure of health from the SF-36. J Health Econ 21: 271292.[Crossref]
  44. Siqueira JB, Martelli CM, Maciel IJ, Oliveira RM, Ribeiro MG, Amorim FP, Moreira BC, Cardoso DD, Souza WV, Andrade AL, , 2004. Household survey of dengue infection in central Brazil: spatial point pattern analysis and risk factors assessment. Am J Trop Med Hyg 71: 646651.
  45. Endy TP, Chunsuttiwat S, Nisalak A, Libraty DH, Green S, Rothman AL, Vaughn DW, Ennis FA, , 2002. Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol 156: 4051.[Crossref]
  46. Burke DS, Nisalak A, Johnson DE, Scott RM, , 1988. A prospective study of dengue infections in Bangkok. Am J Trop Med Hyg 38: 172180.
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  • Received : 01 Feb 2011
  • Accepted : 14 Jul 2011

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