1921
Volume 84, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

We determined the Human Blood Index (HBI) of malaria mosquito vectors in Equatorial Guinea. We used a polymerase chain reaction (PCR)-based methodology to identify blood meal sources in engorged mosquitoes. We observed high HBI values, indicating that these vectors are highly anthropophilic despite intensive intradomicillary application of residual insecticides. Our results suggest that estimating the HBI can be a relatively simple and easy way to evaluate the efficacy of antimalaria interventions where an observed diversion to non-human hosts may successfully contribute to the interruption of malaria transmission.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.2011.10-0463
2011-02-04
2019-07-21
Loading full text...

Full text loading...

/deliver/fulltext/14761645/84/2/298.html?itemId=/content/journals/10.4269/ajtmh.2011.10-0463&mimeType=html&fmt=ahah

References

  1. Lardeux F, Loayza P, Bouchite B, Chavez T, , 2007. Host choice and human blood index of Anopheles pseudopunctipennis in a village of the Andean valleys of Bolivia. Malar J 22: 68. [Google Scholar]
  2. Macdonald G, , 1957. The Epidemiology and Control of Malaria. London, UK: Oxford University Press. [Google Scholar]
  3. Garrett-Jones C, , 1964. The Human Blood Index of malaria vectors in relation to epidemiological assessment. Bull World Health Organ 30: 241261. [Google Scholar]
  4. Muirhead-Thomson RC, , 1951. Mosquito behaviour in relation to malaria transmission and control in the tropics. London: Edward Arnold & Co. 5670. [Google Scholar]
  5. Sousa CA, Pinto J, Almeida AP, Ferreira C, do Rosario VE, Charlwood JD, , 2001. Dogs as a favored host choice of Anopheles gambiae sensu stricto (Diptera: Culicidae) of São Tomé West Africa. J Med Entomol 38: 122125.[Crossref] [Google Scholar]
  6. Teklehaimanot HD, Teklehaimanot A, Kiszewski A, Sacramento Rampao H, Sachs JD, , 2009. Malaria in São Tomé and Principe: on the brink of elimination after 3 years of effective antimalarial measures. Am J Trop Med Hyg 80: 133140. [Google Scholar]
  7. Duchemin JB, Leongpocktsy JM, Rabarison P, Roux J, Coluzzi M, Costantini C, , 2001. Zoophily of Anopheles arabiensis and An. gambiae in Madagascar demonstrated by odour-baited entry traps. Med Vet Entomol 15: 5057.[Crossref] [Google Scholar]
  8. Medical Care Development International, 2006. EGMCI/ BIMCP. Available at: http://mcdi.mcd.org/current_malaria.htm. Accessed March 30, 2010. [Google Scholar]
  9. Kleinschmidt I, Torrez M, Schwabe C, Benavente L, Seocharan I, Jituboh D, Nseng G, Sharp B, , 2007. Factors influencing the effectiveness of malaria control in Bioko Island, equatorial Guinea. Am J Trop Med Hyg 76: 10271032. [Google Scholar]
  10. Sharp BL, Ridl FC, Govender D, Kuklinski J, Kleinschmidt I, , 2007. Malaria vector control by indoor residual insecticide spraying on the tropical island of Bioko, Equatorial Guinea. Malar J 6: 52.[Crossref] [Google Scholar]
  11. Kleinschmidt I, Sharp B, Benavente LE, Schwabe C, Torrez M, Kuklinski J, Morris N, Raman J, Carter J, , 2006. Reduction in infection with Plasmodium falciparum 1 year after the introduction of malaria control interventions on Bioko Island, Equatorial Guinea. Am J Trop Med Hyg 74: 972978. [Google Scholar]
  12. Ridl FC, Bass C, Torrez M, Govender D, Ramdeen V, Yellot L, Edu AE, Schwabe C, Mohloai P, Maharaj R, Kleinschmidt I, , 2008. A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: their role in malaria transmission and the incidence of insecticide resistance alleles. Malar J 7: 194.[Crossref] [Google Scholar]
  13. Cohnstaedt LW, Gillen JI, Munstermann LE, , 2008. Light-emitting diode technology improves insect trapping. J Am Mosq Control Assoc 24: 331334.[Crossref] [Google Scholar]
  14. Silver JB, , 2008. Mosquito Ecology: Field Sampling Methods. New York, NY: Springer, 372492.[Crossref] [Google Scholar]
  15. Scott JA, Brogdon WG, Collins FH, , 1993. Identification of single specimens of the Anopheles gambiae complex by the polymerase chain reaction. Am J Trop Med Hyg 49: 520529. [Google Scholar]
  16. Kengne P, Antonio-Nkondjio C, Awono-Ambene HP, Simard F, Awolola TS, Fontenille D, , 2007. Molecular differentiation of three closely related members of the mosquito species complex, Anopheles moucheti, by mitochondrial and ribosomal DNA polymorphism. Med Vet Entomol 21: 177182.[Crossref] [Google Scholar]
  17. Kengne P, Awono-Ambene P, Antonio-Nkondjio C, Simard F, Fontenille D, , 2003. Molecular identification of the Anopheles nili group of African malaria vectors. Med Vet Entomol 17: 6774.[Crossref] [Google Scholar]
  18. Cohuet A, Simard F, Toto JC, Kengne P, Coetzee M, Fontenille D, , 2003. Species identification within the Anopheles funestus group of malaria vectors in Cameroon and evidence for a new species. Am J Trop Med Hyg 69: 200205. [Google Scholar]
  19. Kent RJ, Norris DE, , 2005. Identification of mammalian blood meals in mosquitoes by a multiplexed polymerase chain reaction targeting cytochrome B. Am J Trop Med Hyg 73: 336342. [Google Scholar]
  20. Tyler DD, , 1992. The Mitochondrion in Health and Disease. New York, NY: VCH Publishers, 95146. [Google Scholar]
  21. Mukabana WR, Takken W, Seda P, Killeen GF, Hawley WA, Knols BGJ, , 2002. Analysis of arthropod blood meals using molecular genetic markers. Trends Parasitol 18: 505509.[Crossref] [Google Scholar]
  22. Kocher TD, White TJ, Erlich HA, , 1989. , ed. PCR Technology: Principles and Applications for DNA Amplification. New York, NY: Stockton Press, 137147. [Google Scholar]
  23. Loyola EG, Rodríguez MH, González L, Arredondo JI, Bown DN, Vaca MA, , 1990. Effect of indoor residual spraying of DDT and bendiocarb on the feeding patterns of Anopheles pseudopunctipennis in Mexico. J Am Mosq Control Assoc 6: 635640. [Google Scholar]
  24. Kaburi JC, Githuto JN, Muthami L, Ngure PK, Mueke JM, Mwandawiro CS, , 2009. Effects of long-lasting insecticidal nets and zooprophylaxis on mosquito feeding behaviour and density in Mwea, central Kenya. J Vector Borne Dis 46: 184190. [Google Scholar]
  25. Diatta M, Spiegel A, Lochouarn L, Fontenille D, , 1998. Similar feeding preferences of Anopheles gambiae and An. arabiensis in Senegal. Trans R Soc Trop Med Hyg 92: 270272.[Crossref] [Google Scholar]
  26. Tirados I, Costantini C, Gibson G, Torr SJ, , 2006. Blood-feeding behaviour of the malaria mosquito Anopheles arabiensis: implications for vector control. Med Vet Entomol 20: 425437.[Crossref] [Google Scholar]
  27. Githeko AK, Service MW, Mbogo CM, Atieli FK, Juma FO, , 1994. Origin of blood meals in indoor and outdoor resting malaria vectors in western Kenya. Acta Trop 58: 307316.[Crossref] [Google Scholar]
  28. Okwa OO, Akinmolayan FI, Carter V, Hurd H, , 2009. Transmission dynamics of malaria in four selected ecological zones of Nigeria in the rainy season. Ann Afr Med 8: 19.[Crossref] [Google Scholar]
  29. Wanji S, Tanke T, Atanga SN, Ajonina C, Nicholas T, Fontenille D, , 2003. Anopheles species of the mount Cameroon region: biting habits, feeding behaviour and entomological inoculation rates. Trop Med Int Health 8: 643649.[Crossref] [Google Scholar]
  30. Tanga MC, Ngundu WI, Judith N, Mbuh J, Tendongfor N, Simard F, Wanji S, , 2010. Climate change and altitudinal structuring of malaria vectors in south-western Cameroon: their relation to malaria transmission. Trans R Soc Trop Med Hyg 104: 453460.[Crossref] [Google Scholar]
  31. Magbity EB, Marbiah NT, Maude G, Curtis CF, Bradley DJ, Greenwood BM, Petersen E, Lines JD, , 1997. Effects of community-wide use of lambdacyhalothrin-impregnated bednets on malaria vectors in rural Sierra Leone. Med Vet Entomol 11: 7986.[Crossref] [Google Scholar]
  32. International Livestock Research Institute, 1992. International Livestock Center for Africa. Available at: http://agtr.ilri.cgiar.org/library/docs/x5474e/x5474e00.htm#Contents. Accessed July 13, 2010. [Google Scholar]
  33. Albrechtsen L, Fa JE, Barry B, Macdonald DW, , 2006. Contrasts in availability and consumption of animal protein in Bioko Island, West Africa: the role of bushmeat. Environ Conserv 32: 340348.[Crossref] [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2011.10-0463
Loading
/content/journals/10.4269/ajtmh.2011.10-0463
Loading

Data & Media loading...

  • Received : 18 Aug 2010
  • Accepted : 26 Oct 2010
  • Published online : 04 Feb 2011

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error