1921
Volume 84, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The Moroccan Health Ministry launched a Process of Eliminating Schistosomiasis in 1994. During 2005–2009, the epidemiologic status showed a clear interruption of disease transmission at the national level; only a few residual cases were recorded. Our present study is the first systematic serologic survey to evaluate the transmission status in remaining disease-endemic foci. A study population of 2,382 children born after the date of the last autochthonous cases were selected from provinces with histories of high schistosomiasis transmission (Tata, Chtouka Ait Baha, Errachidia, El Kelaa Des Sraghna, and Beni Mellal). To identify the presence of disease, specific antibodies directed against adult worm microsomal antigens were detected by using an enzyme-linked immunoelectrotransfer blot assay. The results showed an absence of antibodies in all serum samples. Consequently, our findings confirm either a low transmission status or an interruption of schistosomiasis transmission within the last disease endemic foci.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2011.10-0378
2011-01-05
2017-11-21
Loading full text...

Full text loading...

/deliver/fulltext/14761645/84/1/015.html?itemId=/content/journals/10.4269/ajtmh.2011.10-0378&mimeType=html&fmt=ahah

References

  1. Pontes LA, Dias-Neto E, Rabello A, , 2002. Detection by polymerase chain reaction of Schistosoma mansoni DNA in human serum and feces. Am J Trop Med Hyg 66: 157162.
  2. Doumenge JP, Mott KE, , 1984. Global distribution of schistosomiasis: CEGET/WHO atlas. World Health Stat Q 37: 186199.
  3. World Health Organization, 1987. Atlas of the Global Distribution of Schistosomiasis. Rabat, Morocco: CEGET-CNRS/OMS-WHO. 1987.
  4. Laamrani H, Mahjour J, Madsen H, Khallaayoune K, Gryseels B, , 2000. Schistosoma haematobium in Morocco: moving from control to elimination. Parasitol Today 16: 257260.[Crossref]
  5. DELM, 1999. Données épidémiologiques des maladies sous surveillance, Bilan année 1999. Bull Epidemiol Hebd 8.
  6. DELM, 2005–2006. Etat d'Avancement des Programmes de Lutte Contre les Maladies Parasitaires. Rapport Annuel d'Activités, 3951.
  7. Al-Sherbiny MM, Osman AM, Hancock K, Deelder AM, Tsang VC, , 1999. Application of immunodiagnostic assays: detection of antibodies and circulating antigens in human schistosomiasis and correlation with clinical findings. Am J Trop Med Hyg 60: 960966.
  8. DELM, 2003. Données épidémiologiques des maladies sous surveillance, Bilan année 2003. Bull Epidemiol 9.
  9. DELM, 2004. Données épidémiologiques des maladies sous surveillance, Bilan année 2004. Bull Epidemiol Hebd 57–60: 3031.
  10. Connet M, , 1937. Existence d'un foyer de bilharziose vesicale Akka (decouvert pour la premiere fois). Maroc Med 63: 365366.
  11. Anonymous, 1996. Second Project de Developpement de la Petite et Moyenne Hydraulique (4-eme Tranche). Perimetre d'Akka. Rabat, Morocco: Ministry of Agriculture Direction de Amenagements Hydro Agricoles.
  12. Boelee E, Laamrani H, , 2004. Environmental control of schistosomiasis through community participation in a Moroccan oasis. Trop Med Int Health 9: 9971004.[Crossref]
  13. Anonymous, 2007. Report Inter Country Meeting on Strategies to Eliminate Schistosomiasis from the Eastern Mediterranean Region. Musat, Oman.
  14. Brahim O, , 2008. La Bilharziose Uro Genitale dans la Province d'Errachidia; Actualites et Perspective d'Avenir (1997 a 2006). Rabat, Morocco: Faculte de Pharmacie et Medicine de Rabat.
  15. Laaziri M, Benouna M, , 1982. Guide de la Lutte Contre la Bilharziose. Rabat, Morocco: Direction des Affaires Techniques, Ministere de la Sante Publique.
  16. Nhammi H, , 1997. Evaluation des Activities de Depistage des Cas de Bilharziose dans la Province de El Kelaa Des Sraghna. Rabat, Morocco: Institut National de l Administration de la Sante; Ministere de la Sante Publique.
  17. Lahlou M, Berrada R, , 2001. Etude comparative de l'infestation experimentale de deux souches de bulin schistosome au Maroc Tome. Bull Soc Fr Parasitol 25: 19.
  18. Camerlynck P, Alaoui A, Benmansour N, , 1974. Epidemiologic study of Schistosoma haematobium (Bilharz 1852) schistosomiasis in Morocco. Maroc Med 54: 641649.
  19. International Association for Medical Assistance to Travelers, 2009. World Schistosomiasis Risk Chart. Available at: http://www.iamat.org/pdf/World_Schistosomiasis_Risk_Chart.pdf. Accessed March 7, 2010.
  20. Bundy DA, Hall A, Medley GF, Savioli L, , 1992. Evaluating measures to control intestinal parasitic infections. World Health Stat Q 45: 168179.
  21. Montresor A, Crompton DW, Hall A, Bundy DA, Savioli L, , 1998. Guidelines for the Evaluation of Soil-Transmitted Helminthiasis and Schistosomiasis at Community Level. Geneva: World Health Organization.
  22. Uneke CJ, Oyibo PG, Ugwuoru CD, Nwanokwai AP, Iloegbunam RO, , 2007. Urinary schistosomiasis among school age children in Ebonyi State, Nigeria. The Internet Journal of Laboratory Medicine 2. Available at: http://www.ispub.com/journal/the_internet_journal_of_laboratory_medicine/volume_2_number_1_31/article/urinary_schistosomiasis_among_school_age_children_in_ebonyi_state_nigeria.html. Accessed October 8, 2010.
  23. Handali S, Rodriguez S, Noh J, Gonzalez AE, Garcia HH, Gilman RH, Roberts JM, Hancock K, Tsang VC, , 2007. A simple method for collecting measured whole blood with quantitative recovery of antibody activities for serological surveys. J Immunol Methods 320: 164171.[Crossref]
  24. Tsang VC, Hancock K, Maddison SE, Beatty AL, Moss DM, , 1984. Demonstration of species-specific and cross-reactive components of the adult microsomal antigens from Schistosoma mansoni and S. japonicum (MAMA and JAMA). J Immunol 132: 26072613.
  25. Tsang VC, Tsang KR, Hancock K, Kelly MA, Wilson BC, Maddison SE, , 1983. Schistosoma mansoni adult microsomal antigens, a serologic reagent. I. Systematic fractionation, quantitation, and characterization of antigenic components. J Immunol 130: 13591365.
  26. Tsang VC, Wilkins PP, , 1997. Immunodiagnosis of schistosomiasis. Immunol Invest 26: 175188.[Crossref]
  27. Cetron MS, Chitsulo L, Sullivan JJ, Pilcher J, Wilson M, Noh J, Tsang VC, Hightower AW, Addiss DG, , 1996. Schistosomiasis in Lake Malawi. Lancet 348: 12741278.[Crossref]
  28. Hamburger J, Hoffman O, Kariuki HC, Muchiri EM, Ouma JH, Koech DK, Sturrock RF, King CH, , 2004. Large-scale, polymerase chain reaction-based surveillance of Schistosoma haematobium DNA in snails from transmission sites in coastal Kenya: a new tool for studying the dynamics of snail infection. Am J Trop Med Hyg 71: 765773.
  29. Sturrock RF, , 2001. Schistosomiasis epidemiology and control: how did we get here and where should we go? Mem Inst Oswaldo Cruz 96 (Suppl): 1727.[Crossref]
  30. Hancock K, Tsang VC, , 1986. Development and optimization of the FAST-ELISA for detecting antibodies to Schistosoma mansoni . J Immunol Methods 92: 167176.[Crossref]
  31. Ramzy RM, Hillyer GV, , 1993. Evaluation of an ELISA for the diagnosis of human infection with S. haematobium . J Egypt Soc Parasitol 23: 315322.
  32. Hillyer GV, Tsang VC, Vivas-Gonzalez BE, Noh J, Ahn LH, Vorndam V, , 1999. Age-specific decrease in seroprevalence of schistosomiasis in Puerto Rico. Am J Trop Med 60: 313318.
  33. Al-Sherbiny MM, Osman AM, Hancock K, Deelder AM, VC Tsang, , 1999. Application of immunodiagnostic assays: detection of antibodies and circulating antigens in human schistosomiasis and correlation with clinical findings. Am J Trop Med Hyg 60: 960966.
  34. World Health Organization, 1993. The control of schistosomiasis. Second report of the WHO Expert Committee. World Health Organ Tech Rep Ser 830: 186.
  35. Laamrani H, Khallaayoune K, Madsen H, Mahjour J, Gryseels B, , 2000. New challenges in schistosomiasis control in Morocco. Acta Trop 77: 6167.[Crossref]
  36. EMRO Report of Schistosomiasis, 2007. Inter-Country Meeting on Strategies to Eliminate Schistosomiasis from the Eastern Mediterranean Region. Muscat, Oman. November 6–8, 2007.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2011.10-0378
Loading
/content/journals/10.4269/ajtmh.2011.10-0378
Loading

Data & Media loading...

  • Received : 02 Jul 2010
  • Accepted : 20 Sep 2010

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error