1921
Volume 84, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Approximately 2 billion persons worldwide are infected with schistosomiasis and soil-transmitted helminthes (STH), many in areas where endemic malaria transmission coexists. Few data exist on associations between these infections. Nested within a larger clinical trial, primigravid and secundigravid women provided blood samples for human immunodeficiency virus (HIV) testing and peripheral malaria films and stool and urine for evaluation of STH and spp. during their initial antenatal clinic visit. The most common parasitic infections were malaria (37.6%), (32.3%), and hookworm (14.4%); 14.2% of women were HIV-infected. infection was associated with lower malarial parasite densities (344 versus 557 parasites/μL blood; < 0.05). In multivariate analysis, HIV and hookworm infection were independently associated with malaria infection (adjusted odds ratio = 1.9 and 95% confidence interval = 1.2–3.0 for HIV; adjusted odds ratio = 1.9 and 95% confidence interval = 1.03–3.5 for hookworm). Concurrent helminthic infection had both positive and negative effects on malaria parasitemia among pregnant women in Malawi.

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  • Received : 29 Mar 2010
  • Accepted : 02 Dec 2010
  • Published online : 04 Mar 2011

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