1921
Volume 83, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6%, and 17.5% of infected residents were asymptomatic. Arthralgia was reported up to 3 months after infection, but there were no reports of long-term functional dependence or depression. Symptomatic and seropositive residents were significantly more likely to live in the area with the most dense housing and commercial activities. CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2010.10-0279
2010-12-06
2017-11-24
Loading full text...

Full text loading...

/deliver/fulltext/14761645/83/6/1245.html?itemId=/content/journals/10.4269/ajtmh.2010.10-0279&mimeType=html&fmt=ahah

References

  1. Lam SK, Chua KB, Hooi PS, Rahimah MA, Kumari S, Tharmaratnam M, Chuah SK, Smith DW, Sampson IA, , 2001. Chikungunya infection—an emerging disease in Malaysia. Southeast Asian J Trop Med Public Health 32: 447451.
  2. AbuBakar S, Sam IC, Wong PF, MatRahim N, Hooi PS, Roslan N, , 2007. Reemergence of endemic Chikungunya, Malaysia. Emerg Infect Dis 13: 147149.[Crossref]
  3. Kumarasamy V, Prathapa S, Zuridah H, Chem YK, Norizah I, Chua KB, , 2006. Re-emergence of Chikungunya virus in Malaysia. Med J Malaysia 61: 221225.
  4. Pavri K, , 1986. Disappearance of Chikungunya virus from India and Southeast Asia. Trans R Soc Trop Med Hyg 80: 491.[Crossref]
  5. Noridah O, Paranthaman V, Nayar SK, Masliza M, Ranjit K, Norizah I, Chem YK, Mustafa B, Kumarasamy V, Chua KB, , 2007. Outbreak of Chikungunya due to virus of Central/East African genotype in Malaysia. Med J Malaysia 62: 323328.
  6. Sam IC, Chan YF, Chan SY, Loong SK, Chin HK, Hooi PS, Ganeswrie R, AbuBakar S, , 2009. Chikungunya virus of Asian and Central/East African genotypes in Malaysia. J Clin Virol 46: 180183.[Crossref]
  7. Google Maps, 2010. Bagan Panchor Dalam. Available at: http://maps.google.com/maps?q=4.533+100.633+(Bagan+panchor+dalam)&l=4.533,http://maps.google.com/maps?q=4.533+100.633&spn=05.0,http://maps.google.com/maps?q=4.533+05.0&t=k&hl=en. Accessed July 31, 2010.
  8. Mahoney FI, Barthel DW, , 1965. Functional evaluation: the Barthel index. Md State Med J 14: 6165.
  9. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC, , 1998. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59 (Suppl 20): 2233.
  10. Marchette NJ, Rudnick A, Garcia R, , 1980. Alphaviruses in peninsular Malaysia. II. Serological evidence of human infection. Southeast Asian J Trop Med Public Health 11: 1423.
  11. Sissoko D, Moendandze A, Malvy D, Giry C, Ezzedine K, Solet JL, Pierre V, , 2008. Seroprevalence and risk factors of Chikungunya virus infection in Mayotte, Indian Ocean, 2005–2006: a population-based survey. PLoS One 3: e3066.[Crossref]
  12. Gérardin P, Guernier V, Perrau J, Fianu A, Le Roux K, Grivard P, Michault A, de Lamballerie X, Flahault A, Favier F, , 2008. Estimating Chikungunya prevalence in La Réunion Island outbreak by serosurveys: two methods for two critical times of the epidemic. BMC Infect Dis 8: 99.[Crossref]
  13. Sergon K, Yahaya AA, Brown J, Bedja SA, Mlindasse M, Agata N, Allaranger Y, Ball MD, Powers AM, Ofula V, Onyango C, Konongoi LS, Sang R, Njenga MK, Breiman RF, , 2007. Seroprevalence of Chikungunya virus infection on Grande Comore Island, Union of the Comoros, 2005. Am J Trop Med Hyg 76: 11891193.
  14. Sergon K, Njuguna C, Kalani R, Ofula V, Onyango C, Konongoi LS, Bedno S, Burke H, Dumilla AM, Konde J, Njgenga MK, Sang R, Breiman RF, , 2008. Seroprevalence of Chikungunya virus (CHIKV) infection on Lamu Island, Kenya, October 2004. Am J Trop Med Hyg 78: 333337.
  15. Moro ML, Gagliotti C, Silvi G, Angelini R, Sambri V, Rezza G, Massimiliani E, Mattivi A, Grilli E, Finarelli AC, Spataro N, Pierro AM, Seyler T, Macini P, , Chikungunya Study Group, 2010. Chikungunya virus in north-eastern Italy: a seroprevalence study. Am J Trop Med Hyg 82: 508511.[Crossref]
  16. Retuya TJA, Jr Ting DL, Dacula BD, Lanada JM, Roque VG, Jr Hugo CT, Ogayon JG, Abad-Viola GB, Roces MCR, , 1998. Chikungunya fever outbreak in an agricultural village in Indang, Cavite, Philippines. Philipp J Microbiol Infect Dis 27: 9396.
  17. Raude J, Setbon M, , 2009. The role of environmental and individual factors in the social epidemiology of Chikungunya disease on Mayotte Island. Health Place 15: 689699.[Crossref]
  18. Honório NA, Nogueira RMR, Codeço CT, Carvalho MS, Cruz OG, Magalhães MAFM, de Araújo JMG, de Araújo ESM, Gomes MQ, Pinheiro LS, da Silva Pinel C, Lourenço-de-Oliveira R, , 2009. Spatial evaluation and modeling of dengue seroprevalence and vector density in Rio de Janeiro, Brazil. PLoS Negl Trop Dis 3: e545.[Crossref]
  19. Porter KR, Beckett CG, Kosasih H, Tan RI, Alisjahbana B, Rudiman PIF, Widjaja S, Listiyaningsih E, Ma'Roef CN, McArdle JL, Parwati I, Sudjana P, Jusuf H, Yuwono D, Wuryadi S, , 2005. Epidemiology of dengue and dengue hemorrhagic fever in a cohort of adults living in Bandung, West Java, Indonesia. Am J Trop Med Hyg 72: 6066.
  20. Borgherini G, Poubeau P, Jossaume A, Gouix A, Cotte L, Michault A, Arvin-Berod C, Paganin F, , 2007. Persistent arthralgia associated with Chikungunya virus: a study of 88 adult patients on Reunion Island. Clin Infect Dis 47: 469475.[Crossref]
  21. Souahoro MK, Gérardin P, Boëlle PY, Perrau J, Fianu A, Pouchot J, Malvy D, Flahault A, Favier F, Hanslik T, , 2009. Impact of Chikungunya virus infection on health status and quality of life: a retrospective cohort study. PLoS One 4: e7800.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2010.10-0279
Loading
/content/journals/10.4269/ajtmh.2010.10-0279
Loading

Data & Media loading...

  • Received : 17 May 2010
  • Accepted : 28 Sep 2010

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error