1921
Volume 83, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The aim of this study was to define the clinical presentation of brucellosis in northern Australia and to assess the long-term impact of brucellosis on individual lives. A retrospective review was conducted to assess 32 patients with brucellosis caused by in Townsville, Australia during 1996–2009. All patients were Caucasian males with a mean age of 35 years. The greatest risk factor for brucellosis was feral pig hunting (94%, n = 30). There was one laboratory-acquired case. The most frequent clinical features included fever (94%, n = 30), fatigue (78%, n = 25) and arthralgia (78%, n = 25). The complication rate was 25% (n = 8). A delay in diagnosis of more than 14 days significantly increased the risk of the patient developing complications (95% confidence interval = 3.20–198.96, = 0.002). The long-term impact of brucellosis was significant; 64% (16) of the patients reporting recurrent symptoms. This study highlights the need for further research on brucellosis caused by .

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.2010.10-0237
2010-10-05
2020-09-30
Loading full text...

Full text loading...

/deliver/fulltext/14761645/83/4/876.html?itemId=/content/journals/10.4269/ajtmh.2010.10-0237&mimeType=html&fmt=ahah

References

  1. Godfroid J, Cloeckaert A, Liautard JP, Kohler S, Fretin D, Walravens K, Garin-Bastuji B, Letesson JJ, 2005. From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis. Vet Res 36: 313326.[Crossref]
    [Google Scholar]
  2. National Notifiable Diseases Surveillance System, 2007. Notifications of Brucellosis. Available at: http://www9.health.gov.au/cda/source/cda-index.cfm. Accessed May 2, 2009.
    [Google Scholar]
  3. Young EJ, 2000. Brucella species. Mandell GL, Douglas RG, Bennett JE, Dolin R, eds. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. Fifth edition. Philadelphia, PA: Churchill Livingstone, 10311034.
    [Google Scholar]
  4. Pappas G, Akritidis N, Bosilkovski M, Tsianos E, 2005. Brucellosis. N Engl J Med 352: 23252336.[Crossref]
    [Google Scholar]
  5. Robson J, Harrison M, Wood R, Tilse MH, McKay AB, Brodribb TR, 1993. Brucellosis: re-emergence and changing epidemiology in Queensland. Med J Aust 159: 153158.
    [Google Scholar]
  6. Centers for Disease Controland Prevention, 2009. Brucella suis infection associated with feral swine hunting – three states, 2007–2008. MMWR Morb Mortal Wkly Rep 58: 618621.
    [Google Scholar]
  7. Mantur BG, Biradar M, Bidri RC, Mulimani MS, Veerappa K, Kariholu P, Patil SB, Mangalgi SS, 2006. Protean clinical manifestations and diagnostic challenges of human brucellosis in adults: 16 years' experience in an endemic area. J Med Microbiol 55: 897903.[Crossref]
    [Google Scholar]
  8. Memish Z, Mah M, Al Mahmoud S, Al Shaalan M, Khan MY, 2000. Brucella bacteraemia: clinical and laboratory observations in 160 patients. J Infect 40: 5963.[Crossref]
    [Google Scholar]
  9. Ruiz-Mesa JD, Sanchez-Gonzalex J, Reguera JM, Martin L, Lopez-Palmero S, Colmenero JD, 2005. Rose Bengal test: diagnostic yield and use for the rapid diagnosis of human brucellosis in emergency departments in endemic areas. Clin Microbiol Infect 11: 221225.[Crossref]
    [Google Scholar]
  10. Hasanjani Roushan MR, Mohrez M, Smailnejad Gangi SM, Soleimani Amiri MJ, Hajiahmadi M, 2004. Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol, northern Iran. Epidemiol Infect 132: 11091114.[Crossref]
    [Google Scholar]
  11. Strategy QFPM. The State of Queensland: Queensland Government Department of Primary Industries, April 2004. Available at: http://www.dpi.qld.gov.au/documents/Biosecurity_EnvironmentalPests/IPA-Feral-Pig-Strategy.pdf. Accessed May 24, 2010.
    [Google Scholar]
  12. Robichaud S, Libman M, Behr M, Rubin E, 2004. Prevention of laboratory-acquired brucellosis. Clin Infect Dis 38: e119e122.[Crossref]
    [Google Scholar]
  13. Bouza E, Sanchez-Carrilo C, Hernangómez S, González MJ, 2005. Laboratory-acquired brucellosis: a Spanish national survey. J Hosp Infect 61: 8083.[Crossref]
    [Google Scholar]
  14. Kokoglu OF, Hosoglu S, Geyik MF, Ayaz C, Akalin S, Buyukbese MA, Cetinkaya A, 2006. Clinical and laboratory features of brucellosis in two university hospitals in southeast Turkey. Trop Doct 36: 4951.[Crossref]
    [Google Scholar]
  15. Andriopoulos P, Tsironi M, Deftereos S, Aessopos A, Assimakopoulos G, 2007. Acute brucellosis: presentation, diagnosis, and treatment of 144 cases. Int J Infect Dis 11: 5257.[Crossref]
    [Google Scholar]
  16. Cutler S, Bouzid M, Cutler R, 2007. Q fever. J Infect 54: 313318.[Crossref]
    [Google Scholar]
  17. Franco MP, Mulder M, Gilman RH, Smits HL, 2007. Human brucellosis. Lancet Infect Dis 7: 775786.[Crossref]
    [Google Scholar]
  18. González-Gay MA, Garcia-Porrua C, Ibañez D, García-País MJ, 1999. Osteoarticular complications of brucellosis in an Atlantic area of Spain. J Rheumatol 26: 141145.
    [Google Scholar]
  19. Geyik MF, Gur A, Nas K, Cevik R, Sarac J, Dikici B, Ayaz C, 2002. Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases. Swiss Med Wkly 132: 98105.
    [Google Scholar]
  20. Spink W, 1964. Host-parasite relationship in human brucellosis with prolonged illness due to suppuration of the liver and spleen. Am J Med Sci 247: 129136.[Crossref]
    [Google Scholar]
  21. Skalsky K, Yahav D, Bishara J, Pitlik S, Leibovici L, Paul M, 2008. Treatment of human brucellosis: systematic review and meta-analysis of randomised control trials. BMJ 336: 701704.[Crossref]
    [Google Scholar]
  22. Spink W, 1960. Current status of therapy of brucellosis in human beings. JAMA 172: 697698.[Crossref]
    [Google Scholar]
  23. Eren S, Bayam G, Ergönül O, Celikbaş A, Pazvantoğlu O, Baykam N, Dokuzoğuz B, Dilbaz N, 2006. Cognitive and emotional changes in neurobrucellosis. J Infect 53: 184189.[Crossref]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2010.10-0237
Loading
/content/journals/10.4269/ajtmh.2010.10-0237
Loading

Data & Media loading...

  • Received : 24 Apr 2010
  • Accepted : 01 Jun 2010
  • Published online : 05 Oct 2010
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error