Volume 83, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



In 2009, giant African pouched rats trained to detect tuberculosis (TB) evaluated sputum samples from 10,523 patients whose sputum had previously been evaluated by smear microscopy. Microscopists found 13.3% of the patients to be TB-positive. Simulated second-line screening by the rats revealed 620 new TB-positive patients, increasing the case detection rate by 44%. These data suggest that the rats may be useful for TB detection in developing countries, although further research is needed.


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  • Received : 26 Mar 2010
  • Accepted : 30 Aug 2010

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