Volume 83, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Abdominal computed tomography (CT) findings of malaria are not well-known even though malaria is a serious infectious disease. To identify abdominal CT findings, we selected 34 of 405 patients who had a positive peripheral blood smear for and had underwent abdominal CT as the malaria group. We also selected 80 patients who had fever and a negative peripheral blood smear as the control group and 120 healthy people as the normal group. We reviewed and analyzed their medical records and CT findings retrospectively. The mean spleen and liver length were significantly larger in the malaria group and the incidence of splenomegaly, splenic focal low attenuation, and spontaneous splenic rupture were much higher in the malaria group ( < 0.05). Although abdominal CT is not an indispensable tool for diagnosis, these CT findings will help in the diagnosis of malaria in patients with fever.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Park JW, Klein TA, Lee HC, Pacha LA, Ryu SH, Yeom JS, Moon SH, Kim TS, Chai JY, Oh MD, Choe KW, , 2003. Vivax malaria: a continuing health threat to the Republic of Korea. Am J Trop Med Hyg 69: 159167. [Google Scholar]
  2. Ozsoy MF, Oncul O, Pekkafali Z, Pahsa A, Yenen OS, , 2004. Splenic complications in malaria: report of two cases from Turkey. J Med Microbiol 53: 12551258.[Crossref] [Google Scholar]
  3. Jimenez BC, Navarro M, Huerga H, Lopez-Velez R, , 2007. Spontaneous splenic rupture due to Plasmodium vivax in a traveler: case report and review. J Travel Med 14: 188191.[Crossref] [Google Scholar]
  4. Kaur D, Wasir V, Gulati S, Bagga A, , 2007. Unusual presentation of Plasmodium vivax malaria with severe thrombocytopenia and acute renal failure. J Trop Pediatr 53: 210212.[Crossref] [Google Scholar]
  5. Yagmur Y, Hamdi Kara I, Aldemir M, Buyukbayram H, Tacyildiz IH, Keles C, , 2000. Spontaneous rupture of malarial spleen: two case reports and review of literature. Crit Care 4: 309313.[Crossref] [Google Scholar]
  6. Bezerra AS, D'Ippolito G, Faintuch S, Szejnfeld J, Ahmed M, , 2005. Determination of splenomegaly by CT: is there a place for a single measurement? AJR Am J Roentgenol 184: 15101513.[Crossref] [Google Scholar]
  7. Erturk SM, Mortele KJ, Binkert CA, Glickman JN, Oliva M-R, Ros PR, Silverman SG, , 2006. CT features of hepatic venoocclusive disease and hepatic graft-versus-host disease in patients after hematopoietic stem cell transplantation. AJR Am J Roentgenol 186: 14971501.[Crossref] [Google Scholar]
  8. Bae K, Jeon K-N, , 2006. CT findings of malarial spleen. Br J Radiol 79: e145e147.[Crossref] [Google Scholar]
  9. Kawai S, Ikeda E, Sugiyama M, Matsumoto J, Higuchi T, Zhang H, Khan N, Tomiyoshi K, Inoue T, Yamaguchi H, Katakura K, Endo K, Matsuda H, Suzuki M, , 2006. Enhancement of splenic glucose metabolism during acute malarial infection: correlation of findings of FDG-PET imaging with pathological changes in a primate model of severe human malaria. Am J Trop Med Hyg 74: 353360. [Google Scholar]
  10. Tangpukdee N, Yew HS, Krudsood S, Punyapradit N, Somwong W, Looareesuwan S, Kano S, Wilairatana P, , 2008. Dynamic changes in white blood cell counts in uncomplicated Plasmodium falciparum and P. vivax malaria. Parasitol Int 57:490494.[Crossref] [Google Scholar]
  11. Makkar RP, Mukhopadhyay S, Monga zA, Gupta AK, , 2002. Plasmodium vivax malaria presenting with severe thrombocytopenia. Braz J Infect Dis 6: 263265.[Crossref] [Google Scholar]
  12. Gorg C, Colle J, Gorg K, Prinz H, Zugmaier G, , 2003. Spontaneous rupture of the spleen: ultrasound patterns, diagnosis and follow-up. Br J Radiol 76: 704711.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 14 Mar 2010
  • Accepted : 17 Sep 2010
  • Published online : 06 Dec 2010

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error