1921
Volume 83, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Neurognathostomiasis is a rare but severe form of human gnathostomiasis. Diagnosis of neurognathostomiasis is made presumably by using clinical manifestations. Serologic tests for neurognathostomiasis are not widely available and limited. We studied 12 patients with diagnoses of neurognathostomiasis at Srinagarind Hospital, Khon Kaen University, Thailand. There were three types of neurognathostomiasis (five patients with intracerebral hemorrhage, one patient with subarachnoid hemorrhage, and six patients with myelitis). All patients were tested for antibodies against by an immunoblotting technique. The sensitivity and specificity of the 21-kD and 24-kD diagnostic bands were 83.3% and 100%, and 91.7% and 100%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value for the 21-kD and 24-kD diagnostic bands were all 100%. Both diagnostic bands are a helpful diagnostic tool for neuro gnathostomiasis and show good diagnostic properties.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2010.10-0113
2010-10-05
2017-09-26
Loading full text...

Full text loading...

/deliver/fulltext/14761645/83/4/927.html?itemId=/content/journals/10.4269/ajtmh.2010.10-0113&mimeType=html&fmt=ahah

References

  1. Nawa Y, , 1991. Historical review and current status of gnathostomiasis in Asia. Southeast Asian J Trop Med Public Health 22: 217219.
  2. Ogata K, Nawa Y, Akahane H, Diaz Camacho SP, Lamothe-Argumedo R, Cruz-Reyes A, , 1998. Gnathostomiasis in Mexico. Am J Trop Med Hyg 58: 316318.
  3. Kraivichian K, Nuchprayoon S, Sitichalernchai P, Chaicumpa W, Yentakam S, , 2004. Treatment of cutaneous gnathostomiasis with ivermectin. Am J Trop Med Hyg 71: 623628.
  4. Brant-Zawadzki M, Wofsy CB, Schechter G, , 1982. CT-evidence of subarachnoid hemorrhage due to presumed gnathostomiasis. West J Med 137: 6567.
  5. Sawanyawisuth K, Chlebicki MP, Pratt E, Kanpittaya J, Intapan PM, , 2009. Sequential imaging studies of cerebral gnathostomiasis with subdural hemorrhage as its complication. Trans R Soc Trop Med Hyg 103: 102104.[Crossref]
  6. Sithinamsuwan P, Chairangsaris P, , 2005. Images in clinical medicine. Gnathostomiasis—neuroimaging of larval migration. N Engl J Med 353: 188.[Crossref]
  7. Sawanyawisuth K, Tiamkao S, Nitinavakarn B, Dekumyoy P, Jitpimolmard S, , 2005. MR imaging findings in cauda equina gnathostomiasis. AJNR Am J Neuroradiol 26: 3942.
  8. Sawanyawisuth K, Tiamkao S, Kanpittaya J, Dekumyoy P, Jitpimolmard S, , 2004. MR imaging findings in cerebrospinal gnathostomiasis. AJNR Am J Neuroradiol 25: 446449.
  9. Boongird P, Phuapradit P, Siridej N, Chirachariyavej T, Chuahirun S, Vejjajiva A, , 1977. Neurological manifestations of gnathostomiasis. J Neurol Sci 31: 279291.[Crossref]
  10. Rusnak JM, Lucey DR, , 1993. Clinical gnathostomiasis: case report and review of the English language literature. Clin Infect Dis 16: 3350.[Crossref]
  11. Anantaphruti MT, Nuamtanong S, Dekumyoy P, , 2005. Diagnostic values of IgG4 in human gnathostomiasis. Trop Med Int Health 10: 10131021.[Crossref]
  12. Laummaunwai P, Sawanyawisuth K, Intapan PM, Chotmongkol V, Wongkham C, Maleewong W, , 2007. Evaluation of human IgG class and subclass antibodies to a 24 kDa antigenic component of Gnathostoma spinigerum for the serodiagnosis of gnathostomiasis. Parasitol Res 101: 703708.[Crossref]
  13. Tapchaisri P, Nopparatana C, Chaicumpa W, Setasuban P, , 1991. Specific antigen of Gnathostoma spinigerum for immunodiagnosis of human gnathostomiasis. Int J Parasitol 21: 315319.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2010.10-0113
Loading
/content/journals/10.4269/ajtmh.2010.10-0113
Loading

Data & Media loading...

  • Received : 21 Feb 2010
  • Accepted : 10 Jun 2010

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error