1921
Volume 83, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

We determined the seroprevalence of and associated risk factors among 963 pregnant women attending an obstetric hospital in Fortaleza, Brazil. Seroprevalences of IgG and IgM against were 68.6% (95% confidence interval [CI] = 65.6–71.6%) and 0.5% (95% CI = 0.06–1.0%), respectively. Seroprevalence of IgG was high in women less than 25 years of age (91.7%) and in low-income women (odds Ratio [OR] = 1.40, 95% CI = 1.02–1.90). Multivariate regression analysis showed that consumption of homemade water ice (adjusted OR = 1.49, 95% CI = 1.09–2.04), vegetables washed with untreated water (adjusted OR = 1.43, 95% CI = 1.05–1.94), consumption of chicken (adjusted OR = 1.49, 95% CI = 1.12–2.0), and dog ownership (adjusted OR= 1.46, 95% CI = 1.07–1.98) were factors associated with IgG seropositivity. Young women in northeastern Brazil living under poor socioeconomic conditions are at highest risk for acquiring infection with . Oocyst contamination of water and soil must be addressed in future prevention strategies.

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References

  1. Dubey JP, Beattie CP, , 1988. Toxoplasmosis of Animals and Man. Boca Raton, FL: CRC Press, 1220. [Google Scholar]
  2. Montoya JG, Rosso F, , 2005. Diagnosis and management of toxoplasmosis. Clin Perinatol 32: 705726.[Crossref] [Google Scholar]
  3. Tenter AM, Heckeroth AR, Weiss LM, , 2000. Toxoplasma gondii: from animals to humans. Int J Parasitol 30: 12171258.[Crossref] [Google Scholar]
  4. Thulliez PD, Joynson DH, Wreghitt TG, , 2001. Maternal and foetal infection. In: , eds. Toxoplasmosis. Cambridge, United Kingdom: Cambridge University Press, 193213.[Crossref] [Google Scholar]
  5. Remington J, McLeod R, Thulliez P, Desmonts G, Remington J, Klein JO, , 2001. Toxoplasmosis: a comprehensive clinical guide. , eds. Infectious Diseases of the Fetus and Newborn Infant. 5th edition, Philadelphia, PA: W.B. Saunders, 205346. [Google Scholar]
  6. Montoya JG, Liesenfeld O, , 2004. Toxoplasmosis. Lancet 363: 19651976.[Crossref] [Google Scholar]
  7. Neto EC, Anele E, Rubim R, Brites A, Schulte J, Becker D, Tuuminen T, , 2000. High prevalence of congenital toxoplasmosis in Brazil estimated in a 3-year prospective neonatal screening study. Int J Epidemiol 29: 941947.[Crossref] [Google Scholar]
  8. Mozzatto L, Procianoy RS, , 2003. Incidence of congenital toxoplasmosis in southern Brazil: a prospective study. Rev Inst Med Trop Sao Paulo 45: 147151.[Crossref] [Google Scholar]
  9. Neto EC, Rubin R, Schulte J, Giugliani R, , 2004. Newborn screening for congenital infectious diseases. Emerg Infect Dis 10: 10681073.[Crossref] [Google Scholar]
  10. Carvalheiro CG, Mussi-Pinhata MM, Yamamoto AY, De Souza CBS, Maciel LM, , 2005. Incidence of congenital toxoplasmosis estimated by neonatal screening: relevance of diagnostic confirmation in asymptomatic newborn infants. Epidemiol Infect 133: 485491.[Crossref] [Google Scholar]
  11. Lago EG, Neto EC, Melamed J, Rucks AP, Presotto C, Coelho JC, Parise C, Vargas PR, Goldbeck AS, Fiori RM, , 2007. Congenital toxoplasmosis: late pregnancy infections detected by neonatal screening and maternal serological testing at delivery. Paediatr Perinat Epidemiol 21: 525531.[Crossref] [Google Scholar]
  12. Varella IS, Canti IC, Santos BR, Coppini AZ, Argondizzo LC, Tonin C, Wagner MB, , 2009. Prevalence of acute toxoplasmosis infection among 41,112 pregnant women and the mother-to-child transmission rate in a public hospital in south Brazil. Mem Inst Oswaldo Cruz 104: 383388.[Crossref] [Google Scholar]
  13. Nash JQ, Chissel S, Jones J, Warburton F, Verlander NQ, , 2005. Risk factors for toxoplasmosis in pregnant women in Kent, United Kingdom. Epidemiol Infect 133: 475483.[Crossref] [Google Scholar]
  14. Birgisdottir A, Asbjornsdottir H, Cook E, Gislason D, Jansson C, Olafsson I, Gislason T, Jogi R, Thjodleifsson B, , 2006. Seroprevalence of Toxoplasma gondii in Sweden, Estonia and Iceland. Scand J Infect Dis 38: 625631.[Crossref] [Google Scholar]
  15. Dubey JP, Jones JL, , 2008. Toxoplasma gondii infection in humans and animals in the United States. Int J Parasitol 38: 12571278.[Crossref] [Google Scholar]
  16. Rosso F, Les JT, Agudelo A, Villalobos C, Chaves JA, Tunubala GA, Messa A, Remington JS, Montoya JG, , 2008. Prevalence of infection with Toxoplasma gondii among pregnant women in Cali, Colombia, South America. Am J Trop Med Hyg 78: 504508. [Google Scholar]
  17. Coelho RA, Kobayashi M, Carvalho LB, Jr, 2003. Prevalence of IgG antibodies specific to Toxoplasma gondii among blood donors in Recife, northeast Brazil. Med Trop Sao Paulo 45: 229231.[Crossref] [Google Scholar]
  18. Rey LC, Ramalho IL, , 1999. Seroprevalence of toxoplasmosis in Fortaleza, Ceara, Brazil. Rev Inst Med Trop Sao Paulo 41: 171174.[Crossref] [Google Scholar]
  19. Varella IS, Wagner MB, Darela AC, Nunes LM, Muller RW, , 2003. Seroprevalence of toxoplasmosis in pregnant women. J Pediatr 79: 6974. [Google Scholar]
  20. Avelino MM, Campos D, Jr Parada JB, Castro AM, , 2004. Risk factors for Toxoplasma gondii infection in women of childbearing age. Braz J Infect Dis 8: 164174.[Crossref] [Google Scholar]
  21. Heukelbach J, Meyer-Cirkel V, Moura RC, Gomide M, Queiroz JA, Saweljew P, Liesenfeld O, , 2007. Waterborne toxoplasmosis, northeastern Brazil. Emerg Infect Dis 13: 287289.[Crossref] [Google Scholar]
  22. Spalding SM, Amendoiera MR, Klein CH, Ribeiro LC, , 2005. Serological screening and toxoplasmosis exposures factors among pregnant women in south Brazil. Rev Soc Bras Med Trop 38: 173177.[Crossref] [Google Scholar]
  23. Barbosa IR, de Carvalho Xavier Holanda CM, de Andrade-Neto VF, , 2009. Toxoplasmosis screening and risk factors amongst pregnant females in Natal, northeastern Brazil. Trans R Soc Trop Med Hyg 103: 377382.[Crossref] [Google Scholar]
  24. Bahia-Oliveira LM, Jones JL, Azevedo-Silva J, Alves CC, Orefice F, Addiss DG, , 2003. Highly endemic, waterborne toxoplasmosis in north Rio de Janeiro state, Brazil. Emerg Infect Dis 9: 5562.[Crossref] [Google Scholar]
  25. de Amorim Garcia CA, Orefice F, de Oliveira Lyra C, Gomes AB, Franca M, de Amorim Garcia Filho CA, , 2004. Socioeconomic conditions as determining factors in the prevalence of systemic and ocular toxoplasmosis in northeastern Brazil. Ophthalmic Epidemiol 11: 301317.[Crossref] [Google Scholar]
  26. Hill D, Dubey JP, , 2002. Toxoplasma gondii: transmission, diagnosis and prevention. Clin Microbiol Infect 8: 634640.[Crossref] [Google Scholar]
  27. Bahia-Oliveira LM, Wilken de Abreu AM, Azevedo-Silva J, , 2001. Toxoplasmosis in southeastern Brazil: an alarming situation of highly endemic acquired and congenital infection. Int J Parasitol 31: 133136. [Google Scholar]
  28. Cavalcante GT, Aguiar DM, Chiebao D, Dubey JP, Ruiz VL, Dias RA, Camargo LM, Labruna MB, Gennari SM, , 2006. Seroprevalence of Toxoplasma gondii antibodies in humans from rural Western Amazon, Brazil. J Parasitol 92: 647649.[Crossref] [Google Scholar]
  29. Velasco-Castrejon O, Salvatierra-Izaba B, Valdespino JL, Sedano-Lara AM, Galindo-Virgen S, Magos C, Llausas A, Tapia-Conyer R, Gutierrez G, Sepulveda J, , 1992. Seroepidemiology of toxoplasmosis in Mexico. Salud Publica Mex 34: 222229.[Crossref] [Google Scholar]
  30. Segundo GR, Silva DA, Mineo JR, Ferreira MS, , 2004. A comparative study of congenital toxoplasmosis between public and private hospitals from Uberlandia, MG, Brazil. Mem Inst Oswaldo Cruz 99: 1317.[Crossref] [Google Scholar]
  31. de Moura L, Bahia-Oliveira LM, Wada MY, Jones JL, Tuboi SH, Carmo EH, Ramalho WM, Camargo NJ, Trevisan R, Graca RM, da Silva AJ, Moura I, Dubey JP, Garrett DO, , 2006. Waterborne toxoplasmosis, Brazil, from field to gene. Emerg Infect Dis 12: 326329.[Crossref] [Google Scholar]
  32. Dubey JP, , 1998. Toxoplasma gondii oocyst survival under defined temperatures. J Parasitol 84: 862865.[Crossref] [Google Scholar]
  33. Etheredge GD, Michael G, Muehlenbein MP, Frenkel JK, , 2006. The roles of cats and dogs in the transmission of Toxoplasma infection in Kuna and Embera children in eastern Panama. Rev Panam Salud Publica 16: 176186. [Google Scholar]
  34. Cavalcante GT, Aguilar DM, Camargo LM, Labruna MB, de Andrade HF, Meireles LR, Dubey JP, Thulliez P, Dias RA, Gennari SM, , 2006. Seroprevalence of Toxoplasma gondii antibodies in cats and pigs from rural Western Amazon, Brazil. J Parasitol 92: 863864.[Crossref] [Google Scholar]
  35. Meireles LR, Galisteo AJ, Jr Pompeu E, Andrade HFJ, , 2004. Toxoplasma gondii spreading in an urban area evaluated by seroprevalence in free-living cats and dogs. Trop Med Int Health 9: 876881.[Crossref] [Google Scholar]
  36. Ambroise-Thomas P, Petersen E, , 2000. Congenital Toxoplasmosis: Scientific Background, Clinical Management and Control. Paris: Springer-Verlag.[Crossref] [Google Scholar]
  37. Newton LH, Hall SM, , 1995. A survey of health education material for the primary prevention of congenital toxoplasmosis. Commun Dis Rep CDR Rev 5: 2127. [Google Scholar]
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  • Received : 08 Feb 2010
  • Accepted : 19 Apr 2010

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