1921
Volume 83, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Dengue represents an important public health issue in many tropical areas, leading to high morbidity and the employment of substantial health resources. Even though the number of fatalities related to dengue is unknown, several reports warn about the potential occurrence of severe infections and even death. The clinical spectrum of dengue is highly variable, ranging from a mild flu-like syndrome to severe disease, with shock and hemorrhage. The occurrence of bacterial superinfection, or coinfection, in patients with dengue has been noted by some authors, but the available information comes from anecdotic reports. In this study, we show the clinical and anatomopathological data of a patient infected with dengue, who subsequently died of acute multi-organic failure related to infection. The autopsy revealed a severe disseminated staphylococcal disease and confirmed dengue infection.

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References

  1. Gulati S, Maheshwari A, , 2007. Atypical manifestations of dengue. Trop Med Int Health 12: 10871095.[Crossref] [Google Scholar]
  2. Alejandria MM, , 2009. Dengue haemorrhagic fever or dengue shock syndrome in children. Clin Evid 12: pii: 0917. [Google Scholar]
  3. Halstead SB, , 2007. Dengue. Lancet 370: 16441652.[Crossref] [Google Scholar]
  4. Gibbons RV, Vaughn DW, , 2002. Dengue: an escalating problem. BMJ 324: 15631566.[Crossref] [Google Scholar]
  5. Gubler DJ, Clark GG, , 1995. Dengue/dengue hemorrhagic fever: the emergence of a global health problem. Emerg Infect Dis 1: 5557.[Crossref] [Google Scholar]
  6. Figueiredo LT, , 2006. Viral hemorrhagic fevers in Brazil. Rev Soc Bras Med Trop 39: 203210.[Crossref] [Google Scholar]
  7. Suzuki S, Kitazawa T, Ota Y, Okugawa S, Tsukada K, Nukui Y, Hatakeyama S, Yamaguchi D, Matsuse S, Ishii T, Matsubara T, Yamauchi C, Ota S, Yahagi N, Fukayama M, Koike K, , 2007. Dengue hemorrhagic shock and disseminated candidiasis. Intern Med 46: 10431046.[Crossref] [Google Scholar]
  8. Kohli U, Sahu J, Lodha R, Agarwal N, Ray R, , 2007. Invasive nosocomial aspergillosis associated with heart failure and complete heart block following recovery from dengue shock syndrome. Pediatr Crit Care Med 8: 389391. [Google Scholar]
  9. Tang Y, Kou Z, Tang X, Zhang F, Yao X, Liu S, Jin X, , 2008. Unique impacts of HBV co-infection on clinical and laboratory findings in a recent dengue outbreak in China. Am J Trop Med Hyg 79: 154158. [Google Scholar]
  10. Thangaratham PS, Jeevan MK, Rajendran R, Samuel PP, Tyagi BK, , 2006. Dual infection by dengue virus and Plasmodium vivax in Alappuzha District, Kerala, India. Jpn J Infect Dis 59: 211212. [Google Scholar]
  11. Pancharoen C, Thisyakorn U, , 1998. Coinfections in dengue patients. Pediatr Infect Dis 17: 8182.[Crossref] [Google Scholar]
  12. Hongsiriwon S, , 2002. Dengue hemorrhagic fever in infants. Southeast Asian J Trop Med Public Health 33: 4955. [Google Scholar]
  13. Lee IK, Liu JW, Yang KD, , 2005. Clinical characteristics and risk factors for concurrent bacteremia in adults with dengue hemorrhage fever. Am J Trop Med Hyg 72: 221226. [Google Scholar]
  14. Sudjana P, Jusuf H, , 1998. Concurrent dengue haemorrhagic and typhoid fever in adult: case report. Southeast Asian J Trop Med Public Health 29: 370372. [Google Scholar]
  15. Charrel RN, Abboud M, Durand JP, Brouqui P, Lamballerie XD, , 2003. Dual infection by dengue fever and Shigella sonnei in patient returning from India. Emerg Infect Dis 9: 271.[Crossref] [Google Scholar]
  16. Chai LY, Lim PL, Lee CC, Hsu LY, Teoh YL, Lye DC, Krishnan P, Leo YS, , 2007. Cluster of Staphylococcus aureus and dengue co-infection in Singapore. Ann Acad Med Singapore 36: 847850. [Google Scholar]
  17. Rouse BT, Horohov DW, , 1986. Immunosuppresion in viral infections. Rev Infect Dis 8: 850.[Crossref] [Google Scholar]
  18. Veloso HH, Ferreira JA, De Paiva JM, , 2003. Acute atrial fibrillation during dengue hemorrahgic fever. Braz J Infect Dis 7: 418422.[Crossref] [Google Scholar]
  19. Lum LC, Lam SK, Choy YS, George R, Harun F, , 1996. Dengue encephalitis: a true reality? Am J Trop Med Hyg 54: 256259. [Google Scholar]
  20. Leão RN, Oikawa T, Rosa ES, Yamaki JT, Rodrigues SG, Vasconcelos HB, Sousa MR, Tsukimata JK, Azevedo RS, Vasconcelos PF, , 2002. Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis). Rev Soc Bras Med Trop 35: 401404.[Crossref] [Google Scholar]
  21. Solomon T, Dung NM, Vaughn DW, Kneen R, Thao LT, Raengsakalrach B, Loan AT, Day NP, Farrar J, Myiat KS, Warrell MJ, James WS, Nisalak A, White NJ, , 2000. Neurological manifestations of dengue infection. Lancet 355: 10531059.[Crossref] [Google Scholar]
  22. Hall WC, Crowell TP, Watts DM, Barros VL, Kruger H, Pinheiro F, Peters CJ, , 1991. Demonstration of yellow fever and dengue antigens in formalin-fixed paraffin-embedded human liver by immunohistochemical analysis. Am J Trop Med Hyg 45: 408417. [Google Scholar]
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  • Received : 04 Jan 2010
  • Accepted : 26 Apr 2010

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