1921
Volume 83, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In spite of the high prevalence of malaria in Southeastern Bangladesh, there remains a significant shortage of information regarding the presence of three of five human malaria parasites: , , and . The presence of and has previously never been reported from Bangladesh. We used a genus- and species-specific nested polymerase chain reaction, targeting highly conserved regions of the small subunit ribosomal RNA (SSU rRNA) gene, to investigate the presence of malaria parasites in a total number of 379 patient samples in a survey of patients with febrile illnesses in the Chittagong Hill Tracts in Southeastern Bangladesh. We identified the first cases of in Bangladesh. They were confirmed by sequence analysis; 189 of 379 samples (49.9%; 95% confidence interval = 44.9–54.9%) were positive for sp. by PCR. monoinfections accounted for 68.3% (61.3–74.5%), followed by (15.3%; 10.9–21.2%), (1.6%; 0.5–4.6%), (1.6%; 0.5–4.6%), and mixed infections (13.2%; 9.1–18.8%). We found no evidence of in this region.

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  • Received : 29 Dec 2009
  • Accepted : 15 Mar 2010
  • Published online : 06 Jul 2010
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