Volume 83, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The status of knockdown resistance () mutation was investigated in the major malaria vector Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for mutations, the West African mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African mutation (L1014S) was absent. Moreover, the mortality of s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest allele frequency ever observed in and its implications in malaria vector control in Ethiopia are discussed.


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  • Received : 09 Dec 2009
  • Accepted : 08 Feb 2010

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