1921
Volume 82, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

A 49-year-old immunocompetent white man had a painful ulcer (1.5 cm in diameter) on the left ventrolateral surface of a grossly enlarged tongue. The ulcer was present for two months. Impaired swallowing resulted in substantial weight loss and fatigue. Histopathologic analysis of a punch biopsy specimen indicated numerous Leishman Donovan bodies within macrophages. A polymerase chain reaction confirmed the presence of . Therapy with two cycles of liposomal amphotericin B over a three-month period was administered. Four months after discharge, the ulcer had healed completely and the tongue returned to its normal size and function.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2010.09-0698
2010-04-01
2017-11-23
Loading full text...

Full text loading...

/deliver/fulltext/14761645/82/4/597.html?itemId=/content/journals/10.4269/ajtmh.2010.09-0698&mimeType=html&fmt=ahah

References

  1. Reithinger R, , 2008. Diagnosis and treatment of cutaneous leishmaniasis. Expert Rev Dermatol 3: 315327.[Crossref]
  2. Silveira FT, Lainson R, Corbett CE, , 2004. Clinical and immunopathological spectrum of American cutaneous leishmaniasis with special reference to the disease in Amazonian Brazil: a review. Mem Inst Oswaldo Cruz 99: 239251.[Crossref]
  3. Motta AC, Lopes MA, Ito FA, Carols-Bregni R, de Almeida OP, Roselino AM, , 2007. Oral leishmaniasis: a clinicopathological study of 11 cases. Oral Dis 13: 335340.[Crossref]
  4. Aliglia L, Cobo F, Mediavilla JD, Bravo J, Osuna A, Amador JM, Martin-Sànchez J, Cordero E, Navarro JM, , 2003. Localized mucosal leishmaniasis due to Leishmania (Leishmania) infantum: clinical and microbiologic findings in 31 patients. Medicine (Baltimore) 82: 147158.
  5. Habibzadeh F, Sajedianfarad J, Yadollahie M, , 2005. Isolated lingual leishmaniasis. J Postgrad Med 51: 218219.
  6. Korting GW, Hoede N, , 1973. Ulcerative Leishmania tropica granuloma of the tongue [in German]. Arch Dermatol Forsch 247: 111116 [Crossref]
  7. Sethuraman G, Sharma VK, Salotora P, , 2008. Indian mucosal leishmaniasis due to Leishmania donovani infection. N Engl J Med 358: 313315.[Crossref]
  8. Mahdi M, Elamin EM, Melville SE, Musa AM, Blackwell JM, Mukhtar MM, Elhassan AM, Ibrahim ME, , 2005. Sudanese mucosal leishmaniasis: isolation of a parasite within the Leishmania donovani complex that differs genotypically from L. donovani causing classical visceral leishmaniasis. Infect Genet Evol 5: 2933.[Crossref]
  9. Bosnic S, Gardoni L, Khoury C, Maroli M, , 2006. A review of leishmaniasis in Dalmatia (Croatia) and results from recent surveys on phlebotomine sandflies in three southern countries. Acta Trop 99: 4249.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2010.09-0698
Loading
/content/journals/10.4269/ajtmh.2010.09-0698
Loading

Data & Media loading...

  • Received : 23 Nov 2009
  • Accepted : 26 Dec 2009

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error