Volume 82, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A 49-year-old immunocompetent white man had a painful ulcer (1.5 cm in diameter) on the left ventrolateral surface of a grossly enlarged tongue. The ulcer was present for two months. Impaired swallowing resulted in substantial weight loss and fatigue. Histopathologic analysis of a punch biopsy specimen indicated numerous Leishman Donovan bodies within macrophages. A polymerase chain reaction confirmed the presence of . Therapy with two cycles of liposomal amphotericin B over a three-month period was administered. Four months after discharge, the ulcer had healed completely and the tongue returned to its normal size and function.


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  • Received : 23 Nov 2009
  • Accepted : 26 Dec 2009
  • Published online : 05 Apr 2010

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